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个人简介

Education Background: Doctoral degree| Huazhong Agricultural University| School of Food Science and Technology| 2004 Positions & Employments: 2017.8-2018.8 Department of Biological and Environmental Engineering | Cornell University 2010.10-2011.5 Department of Food Science | Cornell University 2004.7-2019.12 School of Chemical Engineering and Technology | Tianjin University | 天津大学优秀党员 讲授课程: 本科生:《食品营养与分析》、《功能性食品》、《食品化学与分析实验》 研究生:《功能食品研究进展》 学术成就: 1. 天津市年度食品科技创新先进工作者(2013年) 2. 教育部科技进步奖二等奖(2007年) 3. 湖北省科技进步奖二等奖(2006年) 4. 天津市年度食品科技优秀管理带头人(2005年) 科研项目: 1. 天津大学自主创新基金(2021XZC-0065),2021/01-2021/12(主持)。 2. 天津市重点实验室开放课题(kf202002),2020/06-2021/12(主持)。 3. 国家自然科学基金面上项目(31571825),2016/01-2019/12(主持)。 4. 天津市自然科学基金(15JCYBJC30100),2015/4-2018/3(主持)。 5. 天津市重点实验室开放课题(YF117100102),2014/12-2016/12(主持)。 6. 天津大学自主创新基金(2017XQ-0001),2017/01-2017/12(主持)。 7. 国家自然科学基金面上项目(31271979),2013/01-2016/12(主持)。 8. 国家自然科学基金青年基金(30800767),2009/01-2011/12(主持)。 9. 天津大学自主创新基金(2010XJ-0216),2010/01-2010/12(主持)。 10. 企业合作:鹰嘴豆肽开发与研究(G208182),2008/06-2010/06(主持)。 11. 企业合作:灵芝保健饮料研制(G207310),2006/12-2007/12(主持)。 12. 国家科技重大专项(2014Z1-0002),2014/1-2016/12(参加)。 13. 国家自然科学基金青年基金(20806053),2009/01-2011/12(参加)。 14. 国家自然科学基金面上基金(30771613),2008/01-2008/12(参加)。

研究领域

基于天然产物活性和功能因子的化学结构与生物活性,在优化提取、分离和纯化工艺基础上,通过细胞、动物模型等体内外实验,蛋白/基因组学技术结合构效关系解析,开展分子营养学、功能性食品及果蔬品质与代谢工程等领域的理论基础及开发应用研究。主要集中在以下三个方面:(1)功能因子研究及活性评价:构效关系解析、体内外生物活性研究、与生物大分子的相互作用及调控信号通路机制研究。(2)天然产物与食品新资源开发利用:活性成分提取及工艺优化,分离纯化、结构鉴定,生物活性及作用机制研究,功能食品研究与开发。(3)果蔬品质与代谢工程研究。

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

Glycine betaine inhibits postharvest softening and quality decline of winter jujube fruit by regulating energy and antioxidant metabolism Food Chemistry 2023-06 | Journal article DOI: 10.1016/j.foodchem.2023.135445 CONTRIBUTORS: Jingyi Zhang; Chao Wang; Cunkun Chen; Shengli Zhang; Xiaoyang Zhao; Caie Wu; Xiaohong Kou; Zhaohui Xue Research Advancement of Natural Active Components in Alleviating Lung Damage Induced by PM2.5 Food Reviews International 2023-05-19 | Journal article DOI: 10.1080/87559129.2021.1938602 CONTRIBUTORS: Zhaohui Xue; Yumeng Wang; Wancong Yu; Zhijun Zhang; Xiaohong Kou Mechanism of biochanin A alleviating PM2.5-induced oxidative damage based on an XRCC1 knockout BEAS-2B cell model Food & Function 2022 | Journal article DOI: 10.1039/D1FO04312A CONTRIBUTORS: Yue Yu; Ang Li; Shihao Li; Bowen Zheng; Juan Ma; Yazhou Liu; Xiaohong Kou; Zhaohui Xue Mechanisms of Biochanin A Alleviating PM2.5 Organic Extracts-Induced EMT of A549 Cells through the PI3K/Akt Pathway Journal of Natural Products 2022-10-28 | Journal article DOI: 10.1021/acs.jnatprod.2c00457 CONTRIBUTORS: Yumeng Wang; Yixia Zhang; Yonghui Li; Xiaohong Kou; Zhaohui Xue Synergistic Hypolipidemic Effects and Mechanisms of Phytochemicals: A Review Foods 2022-09-09 | Journal article DOI: 10.3390/foods11182774 CONTRIBUTORS: Yazhou Liu; Chunlong Liu; Xiaohong Kou; Yumeng Wang; Yue Yu; Ni Zhen; Jingyu Jiang; Puba Zhaxi; Zhaohui Xue Auxin Response Factors Are Ubiquitous in Plant Growth and Development, and Involved in Crosstalk between Plant Hormones: A Review Applied Sciences 2022-01 | Journal article | Author DOI: 10.3390/app12031360 CONTRIBUTORS: Xiaohong Kou; Xiaoyang Zhao; Bingda Wu; Chao Wang; Caie Wu; Sen Yang; Jiaqian Zhou; Zhaohui Xue Propyl Gallate Treatment Improves the Postharvest Quality of Winter Jujube (Zizyphus jujuba Mill. cv. Dongzao) by Regulating Antioxidant Metabolism and Maintaining the Structure of Peel Foods 2022-01 | Journal article | Author DOI: 10.3390/foods11020237 CONTRIBUTORS: Chao Wang; 存坤 陈; Xiaoyang Zhao; Caie Wu; 晓虹 寇; Zhaohui Xue Biochanin A alleviates oxidative damage caused by the urban particulate matter Food & Function 2021 | Journal article DOI: 10.1039/D0FO02582H CONTRIBUTORS: Zhaohui Xue; Xin Gao; Wancong Yu; Qian Zhang; Weichen Song; Shihao Li; Xu Zheng; Xiaohong Kou Different regulatory mechanisms of plant hormones in the ripening of climacteric and non-climacteric fruits: a review Plant Molecular Biology 2021-12 | Journal article DOI: 10.1007/s11103-021-01199-9 CONTRIBUTORS: Xiaohong Kou; Yuan Feng; Shuai Yuan; Xiaoyang Zhao; Caie Wu; Chao Wang; Zhaohui Xue NAC transcription factors SNAC4 and SNAC9 synergistically regulate tomato fruit ripening by affecting expression of genes involved in ethylene and abscisic acid metabolism and signal transduction Postharvest Biology and Technology 2021-08 | Journal article DOI: 10.1016/j.postharvbio.2021.111555 CONTRIBUTORS: Sen Yang; Jiaqian Zhou; Christopher B. Watkins; Caie Wu; Yanchun Feng; Xiaoyang Zhao; Zhaohui Xue; Xiaohong Kou Mechanism by which salt stress induces physiological responses and regulates tanshinone synthesis Plant Physiology and Biochemistry 2021-07 | Journal article DOI: 10.1016/j.plaphy.2021.04.011 CONTRIBUTORS: Wancong Yu; Yue Yu; Ceng Wang; Zhijun Zhang; Zhaohui Xue The interplay between ABA/ethylene and NAC TFs in tomato fruit ripening: a review Plant Molecular Biology 2021-06 | Journal article DOI: 10.1007/s11103-021-01128-w CONTRIBUTORS: XiaoHong Kou; JiaQian Zhou; Cai E Wu; Sen Yang; YeFang Liu; LiPing Chai; ZhaoHui Xue Investigation on the biological activity of anthocyanins and polyphenols in blueberry Journal of Food Science 2021-02 | Journal article DOI: 10.1111/1750-3841.15598 CONTRIBUTORS: Sen Yang; Chao Wang; Xingyuan Li; Caie Wu; Chen Liu; Zhaohui Xue; Xiaohong Kou Transformation of Biomass DNA into Biodegradable Materials from Gels to Plastics for Reducing Petrochemical Consumption Journal of the American Chemical Society 2020-06-03 | Journal article DOI: 10.1021/jacs.0c02438 CONTRIBUTORS: Dong Wang; Jinhui Cui; Mingzhe Gan; Zhaohui Xue; Jing Wang; Peifeng Liu; Yue Hu; Yehudah Pardo; Shogo Hamada; Dayong Yang et al. Biochanin A protects against PM2.5-induced acute pulmonary cell injury by interacting with the target protein MEK5 Food & Function 2019 | Journal article DOI: 10.1039/C9FO01382B CONTRIBUTORS: Zhaohui Xue; Junyu Wang; Wancong Yu; Dan Li; Yixia Zhang; Fang Wan; Xiaohong Kou Recent advances in aflatoxin B1 detection based on nanotechnology and nanomaterials-A review Analytica Chimica Acta 2019-09 | Journal article DOI: 10.1016/j.aca.2019.04.032 CONTRIBUTORS: Zhaohui Xue; Yixia Zhang; Wancong Yu; Juncai Zhang; Junyu Wang; Fang Wan; Yonghun Kim; Yudong Liu; Xiaohong Kou Effect of abscisic acid (ABA) and chitosan/nano-silica/sodium alginate composite film on the color development and quality of postharvest Chinese winter jujube (Zizyphus jujuba Mill. cv. Dongzao) Food Chemistry 2019-01 | Journal article DOI: 10.1016/j.foodchem.2018.06.151 CONTRIBUTORS: Xiaohong Kou; Yulong He; Yunfei Li; Xiuyu Chen; Yanchun Feng; Zhaohui Xue

学术兼职

天津市食品学会常务理事; 国家自然科学基金委员会同行评议专家、河北省自然科学基金评议专家; Food Research International、Food and Bioprocess Technology、食品科学、食品安全质量检测学报等国内外期刊审稿专家。

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