个人简介
学术成就:
(1)2002 年,高校科学技术奖自然科学二等奖“集成亲和分离方法和理论”,排名第六
(2)2003 年,天津市自然科学奖一等奖“蛋白质分离复性方法和理论研究”,排名第四
(3)2008年,教育部新世纪优秀人才支持计划获得者
(4)2012 年,高等学校科学研究优秀成果奖自然科学二等奖“蛋白质吸附层析的基础研究”,排名第二
科研项目:
(1) 国家自然科学基金面上项目:蛋白A色谱中配基固定与过程高效化研究,负责人,经费80万,2013.01-2016.12;
(2) 国家自然科学基金重点项目:纵向蛋白质色谱过程界面分子行为的解析和应用,排名第3,经费300万,2013.01-2017.12;
(3) 国家863计划课题:肿瘤蛋白分子标志物的研究与开发,排名第二,经费300万,2012.01-2015.12。
专利:
(1) 孙彦,周鑫,史清洪,董晓燕,白姝:高容量大孔琼脂糖凝胶介质的制备方法,中国发明专利,ZL03130027.8
(2) 孙彦,周鑫,史清洪,白姝,董晓燕:高密度核材表面包裹琼脂糖凝胶薄壳介质的制备方法,中国发明专利,ZL 03129755.2
(3) 孙彦,赵雪雁,张磊,史清洪,董晓燕,白姝:利用膨胀床色素亲和色谱纯化重组人干扰素α-2b 的方法,中国发明专利,ZL 200310106725.0
(4) 孙彦,孙国勇,史清洪,董晓燕,白姝:双乳化法制备两类孔型刚性高分子介质的方法,中国发明专利,ZL 200410019065.7
(5) 孙彦,孙国勇,董晓燕,白姝,史清洪:以碳酸钙微粒悬浮液制备超大孔型刚性高分子介质的方法,中国发明专利,ZL 200510013278.3
(6) 孙彦,谭国民,史清洪,董晓燕,白姝:制备型横向电场的体积排阻电色谱分离生物大分子的方法,中国发明专利,ZL 200510014695.X
(7) 孙彦,王冬梅,史清洪,董晓燕,白姝:超大孔纤维素微球蛋白质吸附介质的制备方法,中国发明专利,ZL 200710056590.X
(8) 史清洪,程征,孙彦,董晓燕,白姝:用于免疫球蛋白类蛋白质分离纯化的色谱介质及其制备方法,中国发明专利,ZL 200710059576.5
(9) 徐亮,董晓燕,史清洪,白姝,孙 彦:阴离子聚合物接枝涂层毛细管及用于蛋白质在线富集分析方法,中国发明专利,ZL 200810151254.8
(10) 徐亮,孙 彦,史清洪,白姝,董晓燕:聚乙烯醇涂层毛细管的制备方法及应用,中国发明专利,ZL 200910067986.3
研究领域
生物分离工程
致力于蛋白质色谱的基础理论与技术创新以及固液界面生物分子行为的科学认知
近期论文
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Facile purification and immobilization of organophosphorus hydrolase on protein-inorganic hybrid phosphate nanosheets
Wang Zhenfu,Gao Jie,Shi Qinghong,Dong Xiaoyan,Sun Yan
Page:119-125 ISSN:1004-9541 2023
Container-title:Chinese Journal of Chemical Engineering
Efficient cascade conversion of starch to gluconic acid by a chemoenzymatic system with co-immobilized Au nanoparticles and enzymes
Catalysis Science & Technology
2023 | Journal article
DOI: 10.1039/D2CY01641A
CONTRIBUTORS: Jie Gao; Zhenfu Wang; Ranran Guo; Yang Hu; Xiaoyan Dong; Qinghong Shi; Yan Sun
Removal of bisphenol A by integrated adsorption and biodegradation using immobilized laccase onto defective PCN-224
Journal of Environmental Chemical Engineering
2023-06 | Journal article
DOI: 10.1016/j.jece.2023.110166
CONTRIBUTORS: Zixuan Li; Ziyi Yang; Qinghong Shi; Yan Sun
Shi Qinghong,Jia Lixia.Synthesis of Affinity Chromatography with Biomimetic Peptide Ligand and the Performance in Antibody Purification[J].Journal of Tianjin University(Science and Technology),2022,55(11):1159-1165.
Cascade chiral amine synthesis catalyzed by site-specifically co-immobilized alcohol and amine dehydrogenases
Catalysis Science & Technology
2022 | Journal article
DOI: 10.1039/D2CY00514J
CONTRIBUTORS: Si Liu; Zhenfu Wang; Kun Chen; Linling Yu; Qinghong Shi; Xiaoyan Dong; Yan Sun
Kinetic and molecular insight into immunoglobulin G binding to immobilized recombinant protein A of different orientations
Chu Xinshuang,Yang Xuehui,Shi Qinghong,Dong Xiaoyan,Sun Yan
Page:463040 ISSN:0021-9673 2022
Container-title:Journal of Chromatography A
Increasing immunoglobulin G adsorption in dextran‐grafted protein A gels
Huan Liming,Shi Qing‐Hong
DOI: 10.1002/elsc.202000097
ISSN:1618-0240
Container-title:Engineering in Life Sciences
Zwitterionic polymer-mediated immobilization of organophosphorus hydrolase enhances hydrolysis of methyl parathion by substrate enrichment
Wang Xiaoqi,Wang Zhenfu,Yu Linling,Shi Qinghong,Dong Xiaoyan,Sun Yan
Page:108491 ISSN:1369-703X 2022
Container-title:Biochemical Engineering Journal
Unraveling structure and performance of protein A ligands at liquid – solid interfaces: a multi-techniques analysis
Shen Yi,Chu Xinshuang,Shi Qinghong
ISSN:1004-9541 2021
Container-title:Chinese Journal of Chemical Engineering
In situ investigation of lysozyme adsorption into polyelectrolyte brushes by quartz crystal microbalance with dissipation
You Fenfen,Shi Qing-Hong
ISSN:1004-9541 2021
Container-title:Chinese Journal of Chemical Engineering
Versatile Magnetic Nanoparticles for Spatially Organized Assemblies of Enzyme Cascades: A Comprehensive Investigation of Catalytic Performance
Chu Xinshuang,Shi Qinghong
Page:1437-1446 ISSN:1001-604X 2022
Container-title:Chinese Journal of Chemistry
Kinetic investigation of protein adsorption into polyelectrolyte brushes by quartz crystal microbalance with dissipation: The implication of the chromatographic mechanism
You Fenfen,Shi Qing-Hong
Page:462460 ISSN:0021-9673 2021
Container-title:Journal of Chromatography A
Protein retention in dextran-grafted cation exchange chromatography: The influence of pHs, counterions and polymer structure
Liu Run,Shi Qinghong
Page:1904-1910 ISSN:1004-9541 2020
Container-title:Chinese Journal of Chemical Engineering