个人简介
Educations:
1983.9-1987.7 Undergraduate student, Department of Applied Chemistry in Tianjin University, obtained B.S. in July 1987.
1987.9-1990.6 Graduate student at the Department of Applied Chemistry in Tianjin University, obtained M.S. in June 1990.
1992.9-1996.5 Doctorate candidate in Changchun Institute of Applied Chemistry, obtained Doctor Degree in July 1996
Major Appointments:
2003.6 to Now Professor, School of Chemical Engineering & Technology, Tianjin University
2015.3-2015.9 Visiting Scholar, University of Michigan
2004.5-2004.11 Visiting Scholar, University of South Australia
1990.3-1992.8 Researcher in the Northeast sixth Pharmaceutical Company
1996.6-1998.5 Postdoctor in School of Chemical Engineering & Technology, Tianjin University.
1998.6-2003.6 Associate Professor, School of Chemical Engineering & Technology, Tianjin University
科研项目:
1、国家自然科学基金(青年基金)(物理化学学科)项目:“两亲性聚氨酯水分散体系超分子自组装及特性的研究”,编号:29903007,总经费11万元。2000.1~2002.12。完成。
2、国家自然科学基金(生命科学部)项目“基于高分子自组装体系研究生物膜的分子自组装与功能性”, 编号:30170227, 总经费20万元。2002.1~2004.12。
3、国家十五科技攻关计划 “中药咳喘膏纳米透皮吸收新制剂的研究开发”, 批准号:2001BA310A07-6,起止年月:2002.6~2005.6;经费50万元。
4、国家科技部中澳合作特别基金项目:“基于分子设计和组装开发新型药用高分子材料及纳米药物传递体”,中澳合作,2003.6~2005.6
5、天津市科委重点攻关项目“中药纳米透皮吸收制剂高分子辅料的研制” ,批准号:0131086113,起止年月:2001.9~2003.12;总经费30万元
6、国家自然科学基金(药剂学):“高分子多层次性结构对经皮给药功能性的调控作用”,批准号:30672554,起止年月:2007.1~2009.12;总经费28万元
7、国家自然科学基金(免疫学):“高分子载体结构设计及其对艾滋病疫苗的黏膜免疫促进作用”,30772007,2008~2010,35万
8、天津市重点项目:促进软骨再生修复功能的可注射支架材料及应用技术研究,08JCZDJC17200,30万元,2008.4~2011.3
9、863项目:用于肿瘤介入治疗的纳米材料及其原位凝胶给药系统,2009AA03Z313,100万,2009.5~2011.12
10、国家自然科学基金项目:采用电纺丝技术优化经皮给药系统的结构组合及其功能性,编号:81041085, 总经 费10万元,2011.1~2011.12。
11、参与国家“十一五”国家传染病重大专项课题:联合阻断HIV感染的新型多价生物预防技术研究,2008ZX10001-015-10,2009.10-2012.12,子课题:粘膜预防抗菌剂给药系统研究。
12、 国家自然科学基金面上项目(31271073),通过纳米递送系统上的功能性组装协调siRNA的负载、输运与释放,85万元,2013.1-2016.12。
13、国家自然科学基金面上项目31470963, 持续定位输送模式下的多元协同促进纳米粒肿瘤内药物递送功效,2015-2018, 89万元
14、项目批准号:31671021,项目名称:纳米载体多级结构的精细化与免疫细胞内siRNA递送功效的最优化 ,直接费用:65.00万元,项目起止年月:2017年01月至2020年12月
研究领域
功能高分子材料,高分子自组装与生物膜,纳米材料及技术,药用高分子材料及给药系统
1)可注射温敏原位凝胶材料及其给药系统,以及在抗肿瘤和抗艾滋病粘膜防护中的应用研究;(2)多功能性核酸传递载体及核酸递送系统;(3)经皮给药压敏胶、膜材料和材料对药物经皮渗透的调控作用研究;(4)口服、静脉注射纳米药物的研究
近期论文
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Bioinspired, Anticoagulative, 19F MRI-Visualizable Bilayer Hydrogel Tubes as High Patency Small-Diameter Vascular Grafts
Shuangyang Li, Feng Zhao, Yipeng Tang, Yiqun Zhang, Hui Rong, Lingyuan Liu, Rui Gao, Xiang Liu, Yini Huangfu, Yunpeng Bai, Zujian Feng, Zhigang Guo, Anjie Dong, Weiwei Wang, Deling Kong, Pingsheng Huang
First published: 20 June 2023 https://doi.org/10.1002/smll.202302621
Supramolecular Polymer-Nanomedicine Hydrogel Loaded with Tumor Associated Macrophage-Reprogramming polyTLR7/8a Nanoregulator for Enhanced Anti-Angiogenesis Therapy of Orthotopic Hepatocellular Carcinoma
Xiang Liu, Yini Huangfu, Jingrong Wang, Pengxu Kong, Weijun Tian, Peng Liu, Chuang Fang, Shuangyang Li, Yu Nie, Zujian Feng, Pingsheng Huang, Shengbin Shi, Chuangnian Zhang, Anjie Dong, Weiwei Wang
First published: 25 May 2023 https://doi.org/10.1002/advs.202300637
Solid SiO2-Sealed Mesoporous Silica for Synergistically Combined Use of Inorganic and Organic Filters to Achieve Safe and Effective Skin Protection from All-Band UV Radiation
Qing Ma, Yufeng Zhang, Yini Huangfu, Shangdong Gao, Canhao Zhou, Hui Rong, Liandong Deng, Anjie Dong*, and Jianhua Zhang*
ACS Appl. Mater. Interfaces 2023, 15, 9, 12209–12220
Publication Date:February 27, 2023
https://doi.org/10.1021/acsami.2c21990
A facile and versatile strategy for synthesis of dopamine-functionalized polymers
Ruosi Wang, Mengxiao Sun, Chenyu Wang, Anjie Dong, Jianhua Zhang
First published: 09 November 2022 https://doi.org/10.1002/pol.20220524
Bioinspired and Inflammation-Modulatory Glycopeptide Hydrogels for Radiation-Induced Chronic Skin Injury Repair
Zujian Feng, Yumin Zhang, Chunfang Yang, Xiang Liu, Yini Huangfu, Chuangnian Zhang, Pingsheng Huang, Anjie Dong, Jinjian Liu, Jianfeng Liu, Deling Kong, Weiwei Wang
First published: 02 October 2022 https://doi.org/10.1002/adhm.202201671
Retraction: Influence of 2-(diisopropylamino)ethyl methacrylate on acid-triggered hydrolysis of cyclic benzylidene acetals and their importance in efficient drug delivery
Tang Minjie,Yang Zheng,Feng Zujian,Zhou Junhui,Liu Jinjian,Liu Jianfeng,Wang Weiwei,Zhao Junqiang,Dong Anjie,Deng Liandong
Page:6246-6246 ISSN:1759-9954
Flexible and Zwitterionic Fluorinated Hydrogel Scaffold with High Fluorine Content for Noninvasive 19F Magnetic Resonance Imaging under Ultrahigh Scanning Resolution
Zujian Feng, Qinghua Li, Shuangyang Li, Yushan Zhang, Xiang Liu, Chuangnian Zhang, Anjie Dong, Deling Kong, Weiwei Wang, Pingsheng Huang
First published: 09 November 2022 https://doi.org/10.1002/adhm.202201894
Superhydrophobic and superhydrophilic polyurethane sponge for wound healing
Chen Shangliang,Li Shuangyang,Ye Zhanpeng,Zhang Yufeng,Gao Shangdong,Rong Hui,Zhang Jianhua,Deng Liandong,Dong Anjie
Page:136985 ISSN:1385-8947 Container-title:Chemical Engineering Journal 2022
Covalent Organic Frameworks as Nanocarriers for Improved Delivery of Chemotherapeutic Agents
Liu Weiming,Ma Xinyu,Kheyr Shuayb Mohamed,Dong Anjie,Zhang Jianhua
Page:7215 ISSN:1996-1944 Container-title:Materials 2022
Biomimetic glycopeptide hydrogel coated PCL/nHA scaffold for enhanced cranial bone regeneration via macrophage M2 polarization-induced osteo-immunomodulation
Wang Yaping,Wang Jingrong,Gao Rui,Liu Xiang,Feng Zujian,Zhang Chuangnian,Huang Pingsheng,Dong Anjie,Kong Deling,Wang Weiwei
Page:121538 ISSN:0142-9612 Container-title:Biomaterials 2022
学术兼职
中国生物物理学会纳米生物分会委员
中国微纳米技术学会(纳米科学技术分会)纳米生物材料专业委员会委员
中国癌症协会纳米肿瘤专委会常务委员