Regan, Lynne J. - Yale University - Department of Chemistry

研究领域

Biophysical Chemistry/Organic Chemistry/Chemical Biology

近期论文

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Sawyer, N., Gassaway, B.M., Haimovich, A.D., Isaacs, F.J., Rinehart, J., and Regan, L. Designed Phosphoprotein Recognition in Escherichia coli. ACS Chemical Biology, 9(11): 2502-2507. PDF Zhou, A.Q., O'Hern, C.S., and Regan, L. Predicting the side-chain dihedral angle distributions of nonpolar, aromatic, and polar amino acids using hard sphere models. Proteins, 82(10): 2574-2584. PDF Caballero, D., Määttä, J., Zhou, A.Q., Sammalkorpi, M., O'Hern, C.S., and Regan, L. Intrinsic alpha-helical and beta-sheet conformational preferences: A computational case study of alanine. Protein Science, 23(7): 970-980. PDF Schlingman, D.J., Mack, A.H., Kamenetska, M., Mochrie, S.G.J., and Regan, L. Routes to DNA accessibility: alternative pathways for nucleosome unwinding. Biophysical Journal, 107(2): 384-392. PDF Zhao, Q., Saro, D., Sachpatzidis, A., Singh, T.R., Schlingman, D., Zheng, X.-F., Mack, A., Tsai, M.-S., Mochrie, S., Regan, L., Meetei, A.R., Sung, P., and Xiong, Y. The MHF complex senses branched DNA by binding a pair of crossover DNA duplexes. Nature Communications, 5: 2987. PDF Zhou, A.Q., Caballero, D., O'Hern, C.S., and Regan, L. New Insights into the Interdependence between Amino Acid Stereochemistry and Protein Structure. Biophysical Journal, 105(10): 2403-2411. PDF Mack, A.H*., Schlingman, D.J.*, Kamenetska, M., Collins, R., Mochrie, S.G.J., and Regan, L. The molecular yo-yo method: Live jump detection improves throughput of single-molecule force spectroscopy for out-of-equilibrium transitions. Review of Scientific Instruments, 84(8): 085119. PDF Speltz, E. and Regan, L. White and green screening with circular polymerase extension cloning for easy and reliable cloning. Protein Science, 22(6): 859-864. PDF Sawyer, N.*, Speltz, E.*, and Regan, L. NextGen protein design. Biochemical Society Transactions, 41(5): 1131-1136. PDF Sawyer, N.*, Chen, J.*, and Regan, L. All Repeats Are Not Equal: A Module-Based Approach to Guide Repeat Protein Design. Journal of Molecular Biology, 425(10): 1826-1838. PDF Chen, J., Sawyer, N., and Regan, L. Protein-protein interactions: General trends in the relationship between binding affinity and interfacial buried surface area. Protein Science, 22(4): 510-151. PDF Grove, T.Z., Regan, L., and Cortajarena, A.L. Nanostructured functional films from engineered repeat proteins. Jou Mack, A.H*., Schlingman, D.J.*, Ilagan, R.P., Mochrie, S.G.J., and Regan, L. Kinetics and thermodynamics of phenotype: Unwinding and rewinding the nucleosome. Journal of Molecular Biology, 423(5): 687-701. PDF Mack, A.H., Schlingman, D.J., Regan, L., and Mochrie, S.G.J. Practical Axial Optical Trapping. Review of Scientific Instruments, 83(10): 103106. PDF Grove, T.Z. and Regan, L. New materials from proteins and peptides. Current Opinion in Structural Biology, 22(4): 451-456. PDF Zhou, A.Q., O'Hern, C.S., and Regan, L. The Power of Hard-Sphere Models: Explaining Side-Chain Dihedral Angle Distributions of Thr and Val. Biophysical Journal, 102(10): 2345-2352. PDF Liberles, D.A., Teichmann, S.A., Bahar, I., Bastolla, U., Bloom, J., Bornberg-Bauer, E., Colwell, L.J., de Koning, A.P.J., Dokholyan, N.V., Echave, J. et al. The interface of protein structure, protein biophysics, and molecular evolution. Protein Science, 21(6): 769-785. PDF Grove, T.Z., Forster, J., Pimienta, G., Dufresne, E., and Regan, L. A modular approach to the design of protein-based smart gels. Biopolymers, 97(7): 508-517. PDF De Rosa, L., Cortajarena, A.L., Romanelli, A., Regan, L., and D'Andrea, L.D. Site-specific protein double labeling by expressed protein ligation: applications to repeat proteins. Organic & Biomolecular Chemistry, 10(2): 273-280. PDF rnal of the Royal Society Interface, 10(83): 20130051. PDF