Loria, J. Patrick - Yale University - Department of Chemistry

个人简介

Camille and Henry Dreyfus New Faculty award, 2001 NSF CAREER Award, 2003 Alfred P. Sloan Fellow, 2004

研究领域

Biophysical Chemistry Physical Chemistry

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

"The complexity of protein energy landscapes studied by solution NMR relaxation dispersion experiments",G. Khirich, J.P. Loria J. Phys. Chem. B In Press, (2015). "Enzyme architecture: the effect of replacement and deletion mutations of loop 6 on catalysis by triosephosphate isomerase",X. Zhai, M.K. Go, A.C. Donoghue, T.L. Amyes, S.D. Pegan, Y. Wang, J.P. Loria, A.D. Mesecar, and J.P. Richard Biochemistry 53,3486-3501 (2014). "Conformational motions regulate phosphoryl transfer in related protein tyrosine phosphatases",Sean Whittier, Alvan Hengge, and J.P. Loria Science 341,899-903 (2013). http://www.sciencemag.org/cgi/content/short/341/6148/899 "What's in your buffer? Solute altered millisecond motions detected by solution NMR",M.Wong, G. Khirich, and J.P. Loria Biochemistry 52, 6548-6558 (2013). "Structural mutations that probe the interactions between the catalytic and dianion activation sites in triosephosphate isomerase",X. Zhai, T.L. Amyes, R.K. Wierenga, J.P. Loria, and J.P. Richard Biochemistry 52,5928-5939 (2013). "Accelerating multidimensional NMR and MRI experiments using iterated maps", M.A. Frey, Z.M. Sethna, G.A. Manley, S. Sengupta, K.W. Zilm, J.P. Loria, and S.E. Barrett, J. Magn. Reson, 237, 100-109 (2013). "1H,15N, and 13C resonance assignments for the Yersinia protein tyrosine phosphatase, YopH", Sean Whittier and J.P. Loria Biomol. NMR Assignments Epub ahead of print, Sept, 12 (2013). "MIF intersubunit disulfide mutant antagonist supports activation of CD74 by endogenous MIF trimer at physiological concentrations",Chengpeng Fan, Deepa Rajasekaran, Mansoor Ali Syed, Lin Leng, J.P. Loria, Vineet Bhandari, Richard Bucala, and Elias Lolis Proc. Natl. Acad. Sci. USA 110, 10994-10999 (2013). "Solution NMR and computational methods for understanding protein allostery",Gregory Manley, Ivan Rivalta, and J.P. Loria Featured Article J.Phys.Chem. B 117, 3063-3073 (2013). "Allosteric pathways in the imidazole glycerol phosphate synthase",Ivan Rivalta, Mohammed M. Sultan, Ning-Shiuan Lee, Gregory Manley, J.P. Loria, and Victor Batista Proc. Natl. Acad. Sci. USA 109,E1428-E1436 (2012). "Substrate-dependent millisecond domain motions in DNA Polymerase Beta",Rebecca Berlow, Monalisa Swain, Shibani Dalal, Joann Sweasy, and J.P. Loria J. Mol. Biol. 419,171-182 (2012). "Dynamics in enzymes:solution NMR studies,"J.P. Loria in Encyclopedia of Magnetic Resonance DOI:10.1002/9780470034590.emrstm1241, (2012). "NMR relaxation dispersion studies of large enzymes in solution,"Sean K. Whittier and J.P. Loria Royal Society of Chemistry: Recent Developments in Biomolecular NMR RSC series No. 25 ,Ed. M. Clore & J. Potts, RSC Publishing, Cambridge, 151-162 (2012). "NMR insights into protein allostery,"Gregory Manley and J.P. Loria Arch. Biochem. Biophys. 519, 223 (2012). "Reengineering rate-limiting millisecond enzyme motion by introduction of an unnatural amino acid," Eric D. Watt, Ivan Rivalta, Sean Whittier, Victor Batista and J.P. Loria Biophysical Journal 101, 411 (2011). "Relaxation Dispersion Studies of Enzyme Motions," Nicolas Doucet and J.P. Loria in Advances in Biomedical Spectroscopy: Biomolecular NMR Spectroscopy IOS Press, Vol 3,185 (2011). "The alteration of hydrogen bonding in the vicinity of histidine 48 disrupts millisecond motions in RNase A", Nicolas Doucet, Gennady Khirich, Evgenii Kovrigin, and J.P. Loria Biochemistry 50,1723-1730(2011). "Nanometer propagation of millisecond motions in V-type allostery", James Lipchock and J.P. Loria Structure 18,1596-1607 (2010). "The crystal structure of ribonuclease A in complex with thymidine-3'-monophosphate provides further insight into ligand binding", Nicolas Doucet, Thusitha Jayasundera, Miljan Simonovic and J.P. Loria Prot:Structure, Function, and Bioinformatics 78,2459-2468 (2010). "Helix stabilization precedes aqueous and bilayer catalyzed fiber formation in islet amyloid polypeptide", Jessica A. Williamson, J.P. Loria and A.D. Miranker J. Mol. Biol.. 393,383-396 (2009). "The flexibility of a distant loop modulates active-site motion and product release in ribonuclease A", Nicolas Doucet, Eric Watt and J.P. Loria Biochemistry. 48,7160-7168 (2009). "Millisecond dynamics in the allosteric enzyme imidazole glycerol phosphate synthase (IGPS) from Thermotoga maritima", James Lipchock and J.P. Loria J. Biomol NMR. 45,73-84 (2009). "The role of loop-loop interactions in coordinating motions and enzymatic function in triosephosphate isomerase" Wang, Y., Berlow, R., and J.P. Loria Biochemistry. 48,4548-4556 (2009). "Molecular Interactions by NMR," James Lipchock and J.P. Loria in Methods Mol Biol:Protein Structure, Stability, and Interactions Humana Press (2009).