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研究领域

1. 高分子合成方法与高效的有机化学反应相结合,制备功能性高分子,包括:高真空活性阴离子聚合、氧阴离子聚合、原子转移自由基聚合、开环聚合、CuAAC和Thiol-ene “Click”化学反应、氢硅烷化反应等;2. 刺激敏感性聚合物胶束和水凝胶。

近期论文

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Yang Zhang, Jinlin He*, Dongling Cao, Mingzu Zhang, Peihong Ni*, “Galactosylated reduction and pH dual-responsive triblock terpolymer Gal-PEEP-a-PCL-ss-PDMAEMA: a multifunctional carrier for targeted and simultaneous delivery of doxorubicin and DNA” Polym. Chem., 2014, 5, 5124-5138. Jiao Bian, Ying Hao, Jinlin He*, Wenling Zhang, Mingzu Zhang, Peihong Ni*. “Synthesis and Characterization of a Biodegradable ABC Triblock Terpolymer as Co-Delivery Carrier of Doxorubicin and DNA”. J. Polym. Sci., Part A: Polym. Chem., 2014, doi: 10.1002/pola.27361. Wen-Bin Zhang,‡ Jinlin He,‡ Kan Yue,‡ Chang Liu, Peihong Ni, Roderic P. Quirk,* Stephen Z. D. Cheng*. “Rapid and efficient anionic synthesis of well-defined eight-arm star polymers using octavinylPOSS and poly(styryl)lithium”. Macromolecules, 2012, 45, 8571-8579. (‡ Equal contribution) Jinlin He, Mingzu Zhang, Peihong Ni*. “Rapidly in situ forming polyphosphoester-based hydrogels for injectable drug delivery carriers”. Soft Matter, 2012, 8, 6033-6038. Jinlin He,‡ Kan Yue,‡Yuqing Liu, Xinfei Yu, Peihong Ni, Kevin A. Cavicchi,Roderic P. Quirk, Erqiang Chen*, Stephen Z. D. Cheng*, Wen-Bin Zhang*. “Fluorinated polyhedral oligomeric silsesquioxane-based shape amphiphiles: Molecular design, topological variance, and facile synthesis”. Polym. Chem., 2012, 3, 2112-2120. (‡Equal contribution) Jinlin He, Peihong Ni*, Sai Wang, Haiyan Shao, Mingzu Zhang, Xiulin Zhu*. “Synthesis and physicochemical characterization of biodegradable and pH-responsive hydrogels based on polyphosphoester for protein delivery”. J. Polym. Sci., Part A: Polym. Chem., 2010, 48, 1919-1930. Jinlin He, Peihong Ni*, Cuicui Liu. “Synthesis and characterization of amphiphilic fluorinated pentablock copolymers based on Pluronic F127”. J. Polym. Sci., Part A: Polym. Chem., 2008, 46, 3029-3041. 何金林, 顾子旭, 梁骏, 倪沛红*,“壳聚糖接枝PDMAEMA共聚物的聚集行为”. 高分子材料科学与工程,2008, 24(12), 126-129. 胡健,‡何金林,‡ 张明祖, 倪沛红*. “点击化学在拓扑结构聚合物合成中的应用”,高分子学报, 2013, 3, 300-319. (‡Equal contribution) Ying Hao, Jinlin He, Sen Li, Jian Liu, Mingzu Zhang, Peihong Ni*, “Synthesis of acid-cleavable and fluorescent amphiphilic block copolymer as a combined delivery vector of DNA and doxorubicin”, J. Mater. Chem. B, 2014, 2, 4237-4249. Yunfeng Tao, Jinlin He, Mingzu Zhang, Ying Hao, Jian Liu, Peihong Ni*. “Galactosylated biodegradable poly(ε-caprolactone-co-phosphoester) random copolymer nanoparticles for potent hepatoma-targeting delivery of doxorubicin”, Polym. Chem., 2014, 5, 3443-3452. Ying Hao, Jinlin He, Mingzu Zhang, Yunfeng Tao, Jian Liu, Peihong Ni*. “Synthesis and characterization of novel brush copolymers with biodegradable polyphosphoester side chains for gene delivery”. J. Polym. Sci., Part A: Polym. Chem., 2013, 51, 2150-2160. (Highlighted by MaterialsViews) http://www.materialsviews.com/spotlight-on-polymer-chemistry-volume-51-issue-10/http://www.materialsviews.com/brush-copolymers-for-gene-delivery/ Hairong Wang, Jinlin He, Mingzu Zhang, Yunfeng Tao, Fei Li, Kam Chiu Tam, Peihong Ni*. “Biocompatible and acid-cleavable poly(ε-caprolactone)-acetal-poly(ethylene glycol)-acetal-poly(ε-caprolactone) triblock copolymers: synthesis, characterization and pH-triggered doxorubicin delivery”, J. Mater. Chem. B, 2013, 1, 6596-6607. (Inside Front Cover) 肖燕, 何金林, 陶云锋, 张明祖, 胡健, 倪沛红*. “基于功能化聚磷酸酯嵌段共聚物的微凝胶和水凝胶的制备与表征”, 高分子学报, 2014, 1, 122-130. Kan Yue, Jinlin He, Chang Liu, Mingjun Huang, Xue-Hui Dong, Kai Guo, Peihong Ni, Chrys Wesdemiotis, Roderic P. Quirk,*Stephen Z. D. Cheng,* Wen-Bin Zhang*. “Anionic synthesis of a “Clickable” middle-chain azide-functionalized polystyrene and its application in shape amphiphiles”. Chinese J. Polym. Sci., 2013, 31(1), 71-82. Wen-Bin Zhang, Jinlin He, Xuehui Dong, Chien-Lung Wang, Hui Li, Fuai Teng, Xiaopeng Li, Chrys Wesdemiotis, Roderic P. Quirk*, Stephen Z.D. Cheng*. “Improved synthesis of fullerynes by Fisher esterification for modular and efficient construction of fullerene polymers with high fullerene functionality”. Polymer, 2011, 52, 4221-4226. Wenling Zhang, Jinlin He, Zhuang Liu, Peihong Ni*, Xiulin Zhu*. “Biocompatible and pH-responsive triblock copolymer mPEG-b-PCL-b-PDMAEMA: Synthesis, self-assembly and application”. J. Polym. Sci., Part A: Polym. Chem., 2010, 48, 1079-1091. Mingzu Zhang, Jinlin He, Jiang Mao, Cuicui Liu, Hairong Wang, Yinfeng Huang, Peihong Ni*. “Kinetics of styrene miniemulsion polymerization using poly[(stearyl methacrylate-co-(N, N-dimethylamino)ethyl methacrylate] as surfactant”. Colloid. Surface. A: Physicochem. Eng. Asp.,2010, 360, 190-197. Cuicui Liu, Jinlin He, Qun Zhao, Mingzu Zhang, Peihong Ni*. “Well-defined poly[(dimethylamino)ethyl methacrylate]-b-poly(fluoroalkyl methacrylate) diblock copolymers: Effects of different fluoroalkyl groups on the solution properties”, J. Polym. Sci., Part A: Polym. Chem., 2009, 47, 2702-2712. Xiaofei Li, Mingzu Zhang*, Jinlin He, Dazhao Wu, Juwen Meng, Peihong Ni. “Effects of fluorinated SiO2 nanoparticles on the thermal and electrochemical properties of PP nonwoven/PVdF-HFP composite separator for Li-ion batteries”, J. Membr. Sci., 2014, 455, 368-374. 郝莹, 张洋, 何金林, 尚秀娟, 张明祖, 倪沛红*. “半乳糖胺修饰阳离子型刷形嵌段共聚物的合成与表征”, 化学学报, 2014, 72, 569-576. Guoyi Zhang, Mingzu Zhang, Jinlin He and Peihong Ni*. “Synthesis and characterization of a new multifunctional polymeric prodrug paclitaxel-polyphosphoester-folic acid for targeted drug delivery”, Polym. Chem., 2013, 4, 4515-4525. Jiao Bian, Mingzu Zhang, Jinlin He, Peihong Ni*. “Preparation and self-assembly of double hydrophilic poly(ethylethylene phosphate)-block-poly[2-(succinyloxy)ethyl methacrylate] diblock copolymers for drug delivery”. React. Funct. Polym., 2013, 73, 579-587. Ying Hao, Mingzu Zhang, Jinlin He, Peihong Ni*. “Magnetic DNA vector constructed from PDMAEMA polycation and PEGylated brush-type polyanion with cross-linkable shell”. Langmuir, 2012, 28, 6448-6460. Haiyan Shao, Mingzu Zhang, Jinlin He, Peihong Ni*. “Synthesis and characterization of amphiphilic poly(e-caprolactone)-b-polyphosphoester diblock copolymers bearing multifunctional pendant groups”. Polymer, 2012, 53, 2854-2863. Xu Liu, Peihong Ni*, Jinlin He, Mingzu Zhang. “Synthesis and micellization of pH/temperature-responsive double-hydrophilic diblock copolymers polyphosphoester-block-poly[2-(dimethylamino)ethyl methacrylate] prepared via ROP and ATRP”, Macromolecules, 2010, 43, 4771-4781. Zixu Gu, Yuan Yuan, Jinlin He, Mingzu Zhang, Peihong Ni*. “Facile approach for DNA encapsulation in functional polyion complex for triggered intracellular gene delivery: Design, synthesis, and mechanism”. Langmuir, 2009, 25, 5199-5208. Guixiang Sun, Mingzu Zhang, Jinlin He, Peihong Ni*. “Synthesis of amphiphilic cationic copolymers poly[2-(Methacryloyloxy)ethyl trimethylammonium chloride-co-stearyl methacrylate] and their self-assembly behavior in water and water-ethanol mixtures”, J. Polym. Sci., Part A: Polym. Chem., 2009, 47, 4670-4684. Hu Zhang, Peihong Ni*, Jinlin He, Cuicui Liu. “Novel fluoroalkyl end-capped amphiphilic diblock copolymers with pH/temperature response and self-assembly behavior”. Langmuir, 2008, 24, 4647-4654.

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