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功能性聚多肽的设计合成,聚多肽纳米药物载体,可注射性水凝胶等。

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C. Deng, J.T. Wu, R. Cheng, F.H. Meng, H.A. Klok, and Z.Y. Zhong*, Functional Polypeptide and Hybrid Materials: Precision Synthesis via α-Amino Acid N-Carboxyanhydride Polymerization and Emerging Biomedical Applications, Prog. Polym. Sci. 2014, 39, 330-364. Y.J. Jiang, J. Chen, C. Deng*, E.J. Suuronen, and Z.Y. Zhong*, Click Hydrogels, Microgels and Nanogels: Emerging Platforms for Drug Delivery and Tissue Engineering, Biomaterials 2014, 35, 4969-4985. Y.N. Zhong, F.H. Meng, C. Deng*, and Z.Y. Zhong*, Ligand-Directed Active Tumor-Targeting Polymeric Nanoparticles for Cancer Chemotherapy, Biomacromolecules 2014, 15, 1955-1969. W. Chen, Y. Zou, F.H. Meng, R. Cheng, C. Deng*, J. Feijen, and Z.Y. Zhong*, Glyco-Nanoparticles with Sheddable Saccharide Shells: A Unique and Potent Platform for Hepatoma-Targeting Delivery of Anticancer Drugs, Biomacromolecules 2014, 15, 900-907. W.W. Guo, M. Zheng, Y.N. Zhong, F.H. Meng, C. Deng*, and Z.Y. Zhong*, Poly(ethylene oxide)-graft-Methotrexate Macromolecular Drugs Conjugating via Aminopteridine Ring Exhibit Potent Anticancer Activity, Chin. J. Chem. 2014, 32, 57-65. L.L. Wu, Y. Zou, C. Deng*, R. Cheng, F.H. Meng, and Z.Y. Zhong*, Intracellular Release of Doxorubicin from Core-Crosslinked Polypeptide Micelles Triggered by Both pH and Reduction Conditions, Biomaterials 2013, 34, 5262-5272. J.R. Zhou, P.P. Chen, C. Deng*, F.H. Meng, R. Cheng, and Z.Y. Zhong*, A Simple and Versatile Synthetic Strategy to Functional Polypeptides via Vinyl Sulfone-Substituted L-Cysteine N-Carboxyanhydride, Macromolecules 2013, 46, 6723–6730. Y.N. Zhong, W.J. Yang, H.L. Sun, R. Cheng, F.H. Meng, C. Deng*, and Z.Y. Zhong*, Ligand-Directed Reduction-Sensitive Shell-Sheddable Biodegradable Micelles Actively Deliver Doxorubicin into the Nuclei of Target Cancer Cells, Biomacromolecules 2013, 14, 3723-3730. Y.P. Fan, C. Deng*, R. Cheng, F.H. Meng, and Z.Y. Zhong*, In Situ Forming Hydrogels via Catalyst-Free and Bioorthogonal “Tetrazole–Alkene” Photo-Click Chemistry, Biomacromolecules 2013, 14, 2814-2821. C. Deng, Y.J. Jiang, R. Cheng, F.H. Meng, and Z.Y. Zhong*, Biodegradable Polymeric Micelles for Targeted and Controlled Anticancer Drug Delivery: Promises, Progress and Prospects, Nano Today 2012, 7, 467-480. Y.X. Yu, C. Deng, F.H. Meng, Q. Shi, J. Feijen, and Z.Y. Zhong*, Novel Injectable Biodegradable Glycol Chitosan-Based Hydrogels Crosslinked by Michael-Type Addition Reaction with Oligo(acryloyl carbonate)-b-Poly(ethylene glycol)-b- ligo(acryloyl carbonate) Copolymers, J. Biomed. Mater. Res. Part A 2011, 99A, 316-326. H. Yu, C. Deng, H. Tian, T. Lu, X. Chen, and X. Jing*, Chemo-physical and Biological Evaluation of Poly(L-lysine)-Grafted Chitosan Copolymers, Macromol. Biosci. 2011, 11, 352-361. C. Deng, P. Zhang, B. Vulesevic, D. Kuraitis, F. Li, A.F. Yang, M. Griffith, M. Ruel, and E.J. Suuronen*, A Collagen-Chitosan Hydrogel for Endothelial Differentiation and Angiogenesis, Tissue Eng. Part A 2010, 16, 3099-3109. C. Deng, F.F. Li*, J.M. Hackett, S.H. Chaudhry, F.N. Toll, B. Toye, W. Hodge, and M. Griffith*, Collagen and Glycopolymer Based Hydrogel for Potential Corneal Application, Acta Biomater. 2010, 6, 187-94. W.G Liu, C. Deng (co-first author), C.R. McLaughlin, P. Fagerholm, N.S. Lagali, B. Heyne, J.C. Scaiano, M.A. Watsky, Y. Kato, R. Munger, N. Shinozaki, F.F. Li, and M. Griffith*, Collagen-Phosphorylcholine Interpenetrating Network Hydrogels as Corneal Substitutes, Biomaterials 2009, 30, 1551-1559.

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