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个人简介

Ph.D., Baylor College of Medicine, 2001 M.S., Chinese Academy of Sciences, 1995 B.S., Peking University, 1992

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Jiang, W., Baker, M. L., Jakana, J., Weigele, P. R., King, J., Chiu, W. 2008. Backbone structure of the infectious epsilon 15 virus capsid revealed by electron cryomicroscopy. Nature. 451: 1130-1134. He, Y., Ye, T., Su, M., Zhang, C., Ribbe, A. E., Jiang, W., Mao, C. D. 2008. Hierarchical self-assembly of DNA into symmetric supramolecular polyhedra. Nature. 452: 198-201. Jiang, W., Chiu, W. 2007. Cryoelectron microscopy of icosahedral virus particles. Methods Mol Biol. 369: 345-363. Liu, X. G., Jiang, W., Jakana, J., Chiu, W. 2007. Averaging tens to hundreds of icosahedral particle images to resolve protein secondary structure elements using a Multi-path Simulated Annealing optimization algorithm. Journal of Structural Biology. 160: 11-27. Pope, W. H., Weigele, P. R., Chang, J., Pedulla, M. L., Ford, M. E., Houtz, J. M., Jiang, W., Chiu, W., Hatfull, G. F., Hendrix, R. W., King, J. 2007. Genome sequence, structural proteins, and capsid organization of the cyanophage Syn5: a "horned" bacteriophage of marine synechococcus. J Mol Biol. 368: 966-981. Baker, M. L., Jiang, W., Wedemeyer, W. J., Rixon, F. J., Baker, D., Chiu, W. 2006. Ab initio modeling of the herpesvirus VP26 core domain assessed by CryoEM density. PLoS Comput Biol. 2: e146. Chang, J., Weigele, P., King, J., Chiu, W., Jiang, W. 2006. Cryo-EM Asymmetric Reconstruction of Bacteriophage P22 Reveals Organization of its DNA Packaging and Infecting Machinery. Structure. Jiang, W., Chang, J., Jakana, J., Weigele, P., King, J., Chiu, W. 2006. Structure of epsilon15 bacteriophage reveals genome organization and DNA packaging/injection apparatus. Nature. 439: 612-616. Tang, G., Peng, L., Baldwin, P. R., Mann, D. S., Jiang, W., Rees, I., Ludtke, S. J. 2006. EMAN2: An extensible image processing suite for electron microscopy. J Struct Biol. Baker, M. L., Jiang, W., Rixon, F. J., Chiu, W. 2005. Common ancestry of herpesviruses and tailed DNA bacteriophages. J Virol. 79: 14967-14970. Chiu, W., Baker, M. L., Jiang, W., Dougherty, M., Schmid, M. F. 2005. Electron cryomicroscopy of biological machines at subnanometer resolution. Structure. 13: 363-372. Cong, Y., Jiang, W., Birmanns, S., Zhou, Z. H., Chiu, W., Wriggers, W. 2005. Fast rotational matching of single-particle images. J Struct Biol. 152: 104-112. Jiang, W., Ludtke, S. J. 2005. Electron cryomicroscopy of single particles at subnanometer resolution. Curr Opin Struct Biol. 15: 571-577. Booth, C. R., Jiang, W., Baker, M. L., Zhou, Z. H., Ludtke, S. J., Chiu, W. 2004. A 9 angstroms single particle reconstruction from CCD captured images on a 200 kV electron cryomicroscope. J Struct Biol. 147: 116-127. Baker, M. L., Jiang, W., Bowman, B. R., Zhou, Z. H., Quiocho, F. A., Rixon, F. J., Chiu, W. 2003. Architecture of the herpes simplex virus major capsid protein derived from structural bioinformatics. J Mol Biol. 331: 447-456. Jiang, W., Baker, M. L., Wu, Q., Bajaj, C., Chiu, W. 2003. Applications of a bilateral denoising filter in biological electron microscopy. J Struct Biol. 144: 114-122. Jiang, W., Li, Z., Zhang, Z., Baker, M. L., Prevelige, P. E., Jr., Chiu, W. 2003. Coat protein fold and maturation transition of bacteriophage P22 seen at subnanometer resolutions. Nat Struct Biol. 10: 131-135. Zhou, G., Jiang, W., Zhao, Y., Ma, G., Xin, W., Yin, J., Zhao, B. 2003. Sodium tanshinone IIA sulfonate mediates electron transfer reaction in rat heart mitochondria. Biochem Pharmacol. 65: 51-57. Baker, M. L., Serysheva, II, Sencer, S., Wu, Y., Ludtke, S. J., Jiang, W., Hamilton, S. L., Chiu, W. 2002. The skeletal muscle Ca2+ release channel has an oxidoreductase-like domain. Proc Natl Acad Sci U S A. 99: 12155-12160. Chiu, W., Baker, M. L., Jiang, W., Zhou, Z. H. 2002. Deriving folds of macromolecular complexes through electron cryomicroscopy and bioinformatics approaches. Curr Opin Struct Biol. 12: 263-269. Zhou, G. Y., Jiang, W., Zhao, Y., Ma, G. E., Li, S. G., Xin, W. J., Zhao, B. L. 2002. Interaction between sodium tanshinone IIA sulfonate and the adriamycin semiquinone free radical: A possible mechanism for antagonizing adriamycin-induced cardiotoxity. Research on Chemical Intermediates. 28: 277-289. Jiang, W., Baker, M. L., Ludtke, S. J., Chiu, W. 2001. Bridging the information gap: computational tools for intermediate resolution structure interpretation. J Mol Biol. 308: 1033-1044. Jiang, W., Chiu, W. 2001. Web-based Simulation for Contrast Transfer Function and Envelope Functions. Microsc Microanal. 7: 329-334. Jiang, W., Li, Z., Zhang, Z., Booth, C. R., Baker, M. L., Chiu, W. 2001. Semi-automated icosahedral particle reconstruction at sub-nanometer resolution. J Struct Biol. 136: 214-225. Zhou, Z. H., Baker, M. L., Jiang, W., Dougherty, M., Jakana, J., Dong, G., Lu, G., Chiu, W. 2001. Electron cryomicroscopy and bioinformatics suggest protein fold models for rice dwarf virus. Nat Struct Biol. 8: 868-873.

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