Baxter, Richard - Yale University - Department of Chemistry

个人简介

Boomerang Award, Australian National University, 2009 NIAID Research Scholar (K22) Award, 2010

研究领域

Biophysical Chemistry/Physical Chemistry/Chemical Biology

近期论文

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Dziedzic, P., Cisneros, J.A., Robertson, M.J., Hare, A.A., Danford, N.E., Baxter, R.H.G., Jorgensen, W.L. (2014) "Design, synthesis, and protein crystallography of biaryltriazoles as potent inhibitors of macrophage Migration Inhibitory Factor" JACS, in press. DOI: 10.1021/ja512112j Williams, M. & Baxter, R.H.G. (2014) "The structure and function of thioester-containing proteins in arthropods", Biophys. Rev., 6, 261-272. DOI: 10.1007/s12551-014-0142-6 Han, S., Le, B.V. Hajare, H.S., Baxter, R.H.G., Miller, S.J. (2014) "X-ray crystal structure of teicoplanin A2-2 bound to a catalytic peptide sequence via the carrier protein strategy", J. Org. Chem. 79, 8550-8556. DOI: 10.1021/jo501625f (Featured Article) Le, B.V., Klöck, C., Schatz, A., Nguyen, J.B., Kakani, E.G., Catteruccia, F., Khosla, C., Baxter, R.H.G. (2014) "Dihydroisoxazole inhibitors of Anopheles gambiae transglutaminase AgTG3." Malaria J. 13, 210. DOI: 10.1186/1475-2875-13-210, PMID: 24888439 Melicher, M. S.; Chu, J.; Walker, A. S.; Miller, S. J.; Baxter, R. H. G.; Schepartz, A. (2013) " Organic letters 15, 5048. DOI: 10.1021/ol402381n, PMID: 24032486 Le, B.V., Nguyen, J.B., Logarajah, S, Wang, B., Marcus, J., Williams, H.P., Catteruccia, F., Baxter, R.H.G. (2012) "Characterization of Anopheles gambiae transglutaminase 3 (AgTG3) and its native substrate Plugin." J. Biol. Chem. 288, 4844-4853. DOI: 10.1074/jbc.M112.435347, PMCID: PMC3576089 Le, B.V.*, Williams, M.*, Logarajah, S., Baxter, R.H.G. (2012) "Molecular Basis for Genetic Resistance of Anopheles gambiae to Plasmodium: Structural Analysis of TEP1 Susceptible and Resistant Alleles." PLoS Pathog 8, e1002958. (*equal contribution) DOI: 10.1371/journal.ppat.1002958, PMCID: PMC3464232 Baxter, R.H.G., Steinert, S., Chelliah, Y., Volohonsky, G., Levashina, E.A., Deisenhofer J. (2010) "A heterodimeric complex of the LRR proteins LRIM1 and APL1C regulates complement-like immunity in Anopheles gambiae", Proc. Natl. Acad. Sci. USA 107, 16817-16822. DOI: 10.1073/pnas.1010575107, PMCID: PMC2947905 Fraiture, M.*, Baxter, R.H.G.*, Steinert, S., Chelliah, Y., Frolet, C., Quispe-Tintaya, W., Hoffmann, J.A., Blandin, S.A., Levashina, E.A. (2009) "Two mosquito LRR proteins function as complement control factors in the TEP1-mediated killing of Plasmodium" Cell Host Microbe 5, 273-84. (*equal contribution) DOI: 10.1016/j.chom.2009.01.005, PMID 19286136. Baxter, R.H.G., Chang, C.-I., Chelliah, Y.C., Blandin, S., Levashina, E.A., Deisenhofer, J. (2007) "Structural basis for conserved complement factor-like function in the antimalarial protein TEP1" Proc. Natl. Acad. Sci. USA 104, 11615-11620. DOI: 10.1073/pnas.0704967104, PMCID: PMC1905922