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个人简介

博士,副教授,无党派民主人士,硕士研究生导师,聊城大学农学与农业工程学院水禽疫病基础与防控研究团队负责人。 2008年动物医学本科专业毕业于山东农业大学,2011年获中国农业科学院哈尔滨兽医研究所硕士学位,2014年获中国农业科学院哈尔滨兽医研究所博士学位。2014年7月-2016年4月,在中国农业科学院兰州兽医研究所工作,助理研究员。2016年4月至今在聊城大学工作。 长期从事家禽新发传染病的流行病学、遗传变异、跨种传播与防控技术研究。主持和参加国家自然科学基金、山东省自然科学基金、山东省科技特派员行动计划等科研项目10项。以第一/通讯作者在PLoS pathogens、Journal of Virology、Emerging Microbes & Infections、Science China Life Sciences等国际权威期刊发表研究论文20余篇,多项研究成果在国内外引起了强烈反响,并被科技日报、光明网等大型媒体转载报道。申报国家发明专利和软件著作权9项,转化科技成果2项。积极投身乡村振兴等社会服务,任聊城市企业“科技副总”、山东省优秀科技特派员、 山东省驻企业科技特派员、山东省科技特派员创新创业共同体聊城鹅产业服务团负责人、山东省种畜禽场重点动物疫病净化专家组成员、山东省农科驿站驻站专家。担任Zoonoses、Agriculture Communications、中国家禽青年编委,Vaccines客座编辑,Emerging Microbes & Infections、Frontiers in Microbiology、Virology Journal、Viruses等期刊审稿专家。获山东省畜牧科学技术二等奖、聊城大学自然科学一等奖、聊城大学“光岳英才”、中国农业科学优秀博士毕业论文等奖励。

研究领域

1.动物流感病毒的变异、致病与传播机制 2.水禽疫病防控技术

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

Yanwen Wang1§, Mengjing Wang1§, Hong Zhang1§, Conghui Zhao2§, Yaping Zhang2, Jinyan Shen1, Xiaohong Sun1, Hongke Xu1, Yujiao Xie1, Xinxin Gao1, Pengfei Cui2, Dong Chu3, Yubao Li1, Wenqiang Liu1, Peng Peng3*, Guohua Deng2*, Jing Guo1*, Xuyong Li1*. Prevalence, evolution, replication and transmission of H3N8 avian influenza viruses isolated from migratory birds in eastern China from 2017 to 2021. 2023. Emerging Microbes & Infections. 12(1):2184178. (通讯作者) Yanwen Wang1§, Hong Zhang1§, Mengjing Wang1§, Jing Guo1, Conghui Zhao2, Pengfei Cui2, Guohua Deng2, Dong Chu3, Jinyan Shen1, Xiaohong Sun1, Xinxin Gao1, Yubao Li1, Wenqiang Liu1*, Peng Peng3*, Xuyong Li1*. Genetic analysis of a novel H16N3 virus isolated from a migratory gull in China in 2021 and animal studies of infection. 2022, Microbiology Spectrum. 10(6):e0248422. (通讯作者) Conghui Zhao¶,, Jing Guo¶,, Xianying Zeng, Jianzhong Shi, Guohua Deng, Yaping Zhang, Yanwen Wang, Qi Ma, Xinxin Gao, Pengfei Cui, Liling Liu, Xuyong Li*, Hualan Chen*. Novel H7N7 avian influenza viruses detected in migratory wild birds in eastern China between 2018 and 2020. 2022, Microbes and Infections, 105013. (通讯作者) Yanwen Wang1¶, Mengjing Wang1¶, Hong Zhang1¶, Conghui Zhao2¶, Yaping Zhang2, Guimei He4, Guohua Deng2, Pengfei Cui2, Yubao Li1, Wenqiang Liu1, Jinyan Shen1, Xiaohong Sun1, Wenting Wang1, Xianying Zeng2, Yanbing Li2, Dong Chu3, Peng Peng3*, Jing Guo1*, Hualan Chen2*, Xuyong Li1*. Emergence, evolution, and biological characteristics of H10N4 and H10N8 avian influenza viruses in migratory wild birds detected in eastern China in 2020. 2022, Microbiology Spectrum, 10(2):e0080722. (通讯作者) Jing Guo, Jianing Chen, Yuanyuan Li, Yanbing Li, Guohua Deng, Jianzhong Shi, Liling Liu, Hualan Chen, Xuyong Li*. SUMOylation of matrix protein M1 and filamentous morphology collectively contribute to the replication and virulence of highly pathogenic H5N1 avian influenza viruses in mammals. 2021, Journal of Virology, 96(4):e0163021.(通讯作者) Jing Guo¶, Yanwen Wang¶, Conghui Zhao¶, Xinxin Gao¶, Yaping Zhang, Jiqing Li, Mengjing Wang, Hong Zhang, Wenqiang Liu, Chao Wang, Yingju Xia, Lu Xu, Guimei He, Jinyan Shen, Xiaohong Sun, Wenting Wang, Xinyu Han, Xiaoxuan Zhang, Zhengyang Hou, Xinlin Jin, Na Peng, Yubao Li, Guohua Deng, Pengfei Cui, Qianyi Zhang*, Xuyong Li*, Hualan Chen*. 2021. Molecular characterization, receptor binding property, and replication in chickens and mice of H9N2 avian influenza viruses isolated from chickens, peafowls, and wild birds in eastern China. Emerging Microbes & Infections. 10(1):2098-2112. (通讯作者) Pengfei Cui #, Xianying Zeng #, Xuyong Li #, Yanbing Li #, Jianzhong Shi #, Conghui Zhao, Zhiyuan Qu, Yanwen Wang, Jing Guo, Wenli Gu, Qi Ma, Yuancheng Zhang, Weipeng Lin, Minghui Li, Jingman Tian, Dongxue Wang, Xin Xing, Yanjing Liu, Shuxin Pan, Yaping Zhang, Hongmei Bao, Liling Liu Guobin Tian, Chengjun Li, Guohua Deng, Hualan Chen. 2021. Genetic and biological characteristics of the globally circulating H5N8 avian influenza viruses and the protective efficacy offered by the poultry vaccine currently used in China. Science China Life Sciences. (共同第一作者) Wangjun Tang# , Xuyong Li# , Ling Tang, Tianhou Wang, Guimei He. Characterization of the low-pathogenic H7N7 avian influenza virus inShanghai, China.2021, Poultry Science, 100(2):565-574.(共同第一作者) Jing Guo, Xinxin Gao, Baotao Liu, Yubao Li, Wenqiang Liu, Jianbiao Lu, Cheng Liu, Rui Xue and Xuyong Li*. Mouse adaptation of the H9N2 avian influenza virus causes the downregulation of genes related to innate immune responses and ubiquitin-mediated proteolysis in mice. 2020. Meidcal Microbiology and Immunology, 10.1007. (通讯作者) Shuai Xu#, Xuyong Li#, Jiayun Yang, Zhengxiang Wang, Yane Jia, Lu Han, Liang Wang, Qiyun Zhu. Comparative Pathogenicity and Transmissibilityof Pandemic H1N1, Avian H5N1, and Human H7N9 Influenza Viruses in Tree Shrews. 2019, Frontiers in Microbiology, 10:2955. (共同第一作者) Xuyong Li, Pengfei Cui, Xianying Zeng, Yongping Jiang, Yubao Li, Jiaxin Yang, Yudi Pan, Xinxin Gao, Conghui Zhao, Jinhui Wang, Kai Wang, Guohua Deng, Jing Guo. Characterization of avian influenza H5N3 reassortants isolated from migratory waterfowl and domestic ducks in China from 2015 to 2018, 2019. Transboundary Emerging Diseases, 66(6):2605-2610. Li X, Liu B, Ma S, Cui P, Liu W, Li Y, Guo J, Chen H. High frequency of reassortment after co-infection of chickens with H4N6 and H9N2 influenza viruses and biological characteristics of the reassortants. 2018. Veterinary Microbiology, 222:11-17. Li X, Yang J, Liu B, Jia Y, Guo J, Gao X, Weng S, Yang M, Wang L, Wang LF, Cui J, Chen H, Zhu Q. Co-circulation of H5N6, H3N2, H3N8, and Emergence of Novel Reassortant H3N6 in a Local Community in Hunan Province in China. 2016. Scientific reports, 6:25549. Li X, Fu Y, Yang J, Guo J, He J, Guo J, Weng S, Jia Y, Liu B, Li X, Zhu Q, Chen H. Genetic and biological characterization of two novel reassortant H5N6 swine influenza viruses in mice and chickens. 2015. Infection, genetics and evolution, 36:462-466. Li X, Shi J, Guo J, Deng G, Zhang Q, Wang J, He X, Wang K, Chen J, Li Y, Fan J, Kong H, Gu C, Guan Y, Suzuki Y, Kawaoka Y, Liu L, Jiang Y, Tian G, Li Y, Bu Z, Chen H. Genetics, receptor binding property, and transmissibility in mammals of naturally isolated H9N2 Avian Influenza viruses. 2014. PLoS pathogens, 10:e1004508. Zhang H#, Li X#, Guo J, Li L, Chang C, Li Y, Bian C, Xu K, Chen H, Sun B. The PB2 E627K mutation contributes to the high polymerase activity and enhanced replication of H7N9 influenza virus. 2014. The Journal of General Virology, 95:779-786. (共同第一作者)

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