当前位置: X-MOL首页全球导师 国内导师 › 李顺意

个人简介

学习和工作简历: 1991年9月-1994年7月,湖南师范大学生物学系,理学硕士 1994年9月-1997年7月,中国科学院昆明动物研究所,理学博士 2004年2月-2008年2月,美国佐治亚州立大学化学系,博士后 1997年-今,湖北大学生命科学学院讲师、副教授 科研项目: 1.钙离子与蛇毒磷脂酶A2的结构和功能的关系研究,教育部留学人员回国人员基金,2011-2013年,主持 2.湖北省自然科学基金重点项目(2010CDB04507,2010),主持 3.湖北省教育厅自然科学基金(DC20101007,2010),主持

研究领域

主要研究领域:生物化学与分子生物学、蛋白质化学

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

1.LiS,JiangJ.,ZouJ,QiaoJ,XueS,WeiL,LongR,WangL,CastiblancoA,MaorN,NgoJ,MaoH,LiuL,andYangJ.J.PEGylationofProtein-basedMRIContrastAgentsImprovesRelaxivitiesandBiocompatibilities.JournalofInorganicBiochemistry,2012,107(1),111-118. 2.ZhangG,LiS,etal.EffectsofsaltsonactivityofhalophiliccellulasewithglucomannanaseactivityisolatedfromalkaliphilicandhalophilicBacillussp.BG-CS10.Extremophiles,2012,16,35-42. 3.QiaoJ,LiS,JiangJ,WeiL,LiangR.,WangL.,MaoH.,YangH.,GrossniklausH.,LiuZ.andYangJ.J.HER-2TargetedMolecularMRImagingUsingadenovoDesignedProteinContrastAgent.PLoSONE,6,e18103,2011. 4.Wei,L;Li,S;Yang,J;Ye,Y.;Zou,J;Wang,L;Long,R;Zurkiya,O;Zhao,T;Johnson,J;Qiao,J;Zhou,W;Castiblanco,A;Maor,N;Chen,Y;Mao,H;Hu,X;Yang,JJ;Liu,ZR.Protein-basedMRIContrastAgentsforMolecularImagingofProstateCancer.MolImagingBiol,2010,13,416-423. 5.Li,S;Yang,W;Maniccia,A;Barrow,D,Jr;Tjong,H;Zhou,H;Yang,J.RationaldesignofaCa2+-bindingproteinwithswitchableconformation.FEBS(FederationofEuropeanBiochemicalSocieties)Journal,275,5048-5061,2008. 6.Chen,N;Ye,Y;Zou,J;Li,S;Wang,S;Martin,A;Wohlhueter,R;Yang,J.FluorescencecomplementationviaEF-handinteractions.JBiotechnol.2009,142,205-213. 7.Zhou,Y;Tzeng,W;Ye,Y;Huang,Y;Li,S;Chen,Y;Frey,T;Yang,J.Acysteine-richmetal-bindingdomainfromrubellavirusnon-structuralproteinisessentialforviralproteaseactivityandvirusreplication.BiochemJ.2009,417,477-483. 8.Maniccia,A;Yang,W;Johnson,J;Li,S;Tjong,H;Zhou,H;Shaket,L;Yang,J.Inversetuningofmetalbindingaffinityandproteinstabilitybyalteringchargedcoordinationresiduesindesignedcalciumbindingproteins.PMCBiophys.2009,2,11. 9.Yang,J;Yang,J;Wei,L;Zurkiya,O;Yang,W;Li,S;Zou,J;Zhou,Y;Maniccia,A;Mao,H;Zhao,F;Malchow,R;Zhao,S;Johnson,J;Hu,X;Krogstad,E;Liu,Z.RationalDesignProteinBasedMRIContrastAgentswithHighRelaxivityJournaloftheAmericanChemicalSociety.2008,130,9260-9267. 10.Huang,Y;Zhou,Y;Yang,W;Butters,R;Lee,H;Li,S;Castiblanco,A;Brown,E;Yang,J.IdentificationandDissectionofCa2+-BindingSitesintheExtracellularDomainofCa2+-sensingReceptor.JournalofBiologicalChemistry.2007,282,19000-19010. 11.Maniccia,A;Yang,W;Li,S;Johnson,J;Yang,J.Usingproteindesigntodissecttheeffectofchargedresiduesonmetalbindingandproteinstability.Biochemistry.2006,45(18):5848-5856. 12.Yang,W;Wilkins,A;Li,S;Ye,Y;Yang,J.TheeffectsofCa2+bindingonthedynamicpropertiesofadesignedCa2+–bindingprotein.Biochemistry.2005,44(23):8267-8273. 13.Yang,W;Wilkins,A;Ye,Y;Liu,Z;Li,S;Urbauer,J;Hellinga,H;Kearney,A;vanderMerwe,P;Yang,J.Designofacalcium-bindingproteinwithdesiredstructureinacelladhesionmolecule.JAMCHEMSOC.2005,127,2085-2093

推荐链接
down
wechat
bug