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个人简介

1999年毕业于聊城大学化工学院,获得理学学士;2002年毕业于四川大学化工学院应用化学系,获得理学硕士学位;2005年毕业于中国科学院上海药物研究所,获理学博士学位;2005-2008年新加坡理工学院工作,讲师。2008-2012年澳大利亚科廷大学医学生物学学院进行博士后工作,博士生导师。2013年人才引进中国科学院昆明植物研究所工作至今,副研究员,硕士生导师

研究领域

从事分子模拟与药物设计工作,运用虚拟筛选、构效关系、药效团搜索、从头设计等多种药物设计技术与方法开展创新药物研究

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

1. Zhang, Shuqun,Hou, Bo,Yang, Huaiyu,Zuo, Zhili*,Design and prediction of new acetylcholinesterase inhibitor via quantitative structure activity relationship of huprines derivatives.,Archives of Pharmacal Research,2016,39(1):1-12. 2. Lei Di,Yan-Ni Shi,Yong-Ming Yan,Li-Ping Jiang,Bo Hou,Xin-Long Wang,Zhili Zuo*,Ji-Jun Chen,Yong-Bin Chen,Cui-Ping Yang*,Yong-Xian Cheng*,Natural Products from Aspongopus chinensis and Their Neural Stem Cell Proliferation Stimulating Properties,RSC Advances,2015,5:70985-70991。 3. Wei, Kun,Wang, Gang-Qiang,Bai, Xue,Niu, Yan-Fen,Chen, He-Ping,Wen, Chun-Nan,Li, Zheng-Hui,Dong, Ze-Jun,Zuo, ZhiLi*,Xiong, Wen-Yong*,Liu, Ji-Kai*,Structure-Based Optimization and Biological Evaluation of Pancreatic Lipase Inhibitors as Novel Potential Antiobesity Agents.,Nat Prod Bioprospect,2015,5(3):129-157。 4. Feng-Qing Xu, Fang-Cheng Xu, Bo Hou, Wei-Wei Fan, Cheng-Ting Zi, Yan Li, Fa-Wu Dong, Yu-Qing Liu, Jun Sheng, ZhiLi Zuo*, Jiang-Miao Hu.* Cytotoxic bibenzyl dimers from the stems of Dendrobium fimbriatum Hook. Bioorganic & Medicinal Chemistry Letters, 2014, 24 ,5268–5273. 5. ZhiLi Zuo, Ling Guo, Ricardo L. Mancera, Free Energy of Binding of Coiled-Coil Complexes with Different Electrostatic Environments: The Influence of Force Field Polarisation and Capping. Nat. Prod. Bioprospect. 2014,4(5):285-295. 6. Bo Hou, Pinggui Yi, Zhaoxu Wang, Shuqun Zhang, Jinhua Zhao, Ricardo L. Mancera, Yongxian Cheng and Zhili Zuo*. Assignment of Aromaticity of the Classic Heterobenzenes by Three Aromatic Criteria, Computational and Theoretical Chemistry, 2014, 1046, 20-24 7. Bo Hou, Pinggui Yi, Zhaoxu Wang, Shuqun Zhang, Jinhua Zhao, Ricardo L. Mancera, Yongxian Cheng and Zhili Zuo*. Assignment of Aromaticity of the Classic Heterobenzenes by Three Aromatic Criteria, Computational and Theoretical Chemistry, 2014, 1046, 20-24. 8. Yong-Ming Yan, Jun Ai, Yan-Ni Shi, ZhiLi Zuo, Bo Hou, Jie Luo, and Yong-Xian Cheng*. (±)-Aspongamide A, an N-Acetyldopamine Trimer Isolated from the Insect Aspongopus chinensis, Is an Inhibitor of p-Smad3. Organic Letter, 2014, 16 (2), 532–535. 9. Jing Deng, Ning Li, Hongchuan Liu, Zhili Zuo, Oi Wah Liew, Weijun Xu, Gang Chen, Xiankun Tong, Wei Tang, Jin Zhu, Jianping Zuo,Hualiang Jiang, Cai-Guang Yang, Jian Li,and Weiliang Zhu, Discovery of Novel Small Molecule Inhibitors of Dengue Viral NS2BNS3 Protease Using Virtual Screening and Scaffold Hopping, Journal of Medicinal Chemistry, 2012(55), 6278 – 6293.

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