个人简介
杨轶轩，1975年生，男，副主任医师，博士后。1998年获南京医科大学临床医学系学士学位，2006年获中南大学大学湘雅医院消化内科专业博士学位。2006年9月到重庆医科大学感染性疾病分子生物学教育部重点实验室从事博士后研究，2007年1月-2011年10月到新加坡国立大学蛋白组中心从事肿瘤定量蛋白质组研究。从硕士研究生开始从事肿瘤蛋白质组学研究工作，熟练掌握Itraq,SILAC,ICAT定量蛋白质组学前沿技术。已发表蛋白质组学相关SCI论文14篇。
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(1)WangL,ChenS,ZhangM,LiN,ChenY,SuW,LiuY,LuD,LiS,YangY,LiZ,StupackD,QuP,HuH,XiangR.Legumain:Abiomarkerfordiagnosisandprognosisofhumanovariancancer.JCellBiochem.2012Mar22.doi:10.1002/jcb.24143.
(2)TongSW,YangYX,HuHD,AnX,YeF,HuP,RenH,LiSL,ZhangDZ.Proteomicinvestigationof5-fluorouracilresistanceinahumanhepatocellularcarcinomacellline.JCellBiochem.2012May;113(5):1671-80.
(3)YeF,YangYX,HuHD,TongJB,CaiWJ,ZhangDZ,HuP,LiSL,RenH.Preparationofnovelanti-skimonoclonalantibodies.Hybridoma(Larchmt).2011Aug;30(4):393-5.
(4)YeF,ZhangH,YangYX,HuHD,SzeSK,MengW,QianJ,RenH,YangBL,LuoMY,WuX,ZhuW,CaiWJ,TongJB.Comparativeproteomeanalysisof3T3-L1adipocytedifferentiationusingiTRAQ-coupled2DLC-MS/MS.JCellBiochem.2011Oct;112(10):3002-14
(5)YangYixuan,LimShenKiat,ChoongLeeYee,LeeHuiyin,ChenYunhao,ChongPohKuan,AshktorabHassan,WangTingTing,Salto-TellezManuel,YeohKhayGuan,andLimYoonPin.CathepsinSMediatesGastricCancerCellMigrationandInvasionviaaPutativeNetworkofMetastasis-AssociatedProteins.JournalofProteomeresearch.2010,9(9):4767–4778(SCI影响因子5.132)
(6)Yi-XuanYang,Zhi-QiangXiao,Zhu-ChuChen,Gui-YingZhang,HongYi,Peng-FeiZhang,Jian-LingliandGuoZhu.Proteomeanalysisofmultidrugresistanceinvincristine-resistanthumangastriccancercelllineSGC7901/VCR.Proteomics,2006,6(6):2009-2021.(SCI影响因子4.426)
(7)YangYX,HuHD,ZhangDZ,RengH.Identificationofproteinsresponsibleforthedevelopmentofadriamycinresistanceinhumangastriccancercellsusingcomparativeproteomicsanalysis.JournalofBiochemistryandMolecularBiology,2007,40(6):853-60.(SCI影响因子2.021)
(8)Yi-XuanYang,Zhu-ChuChen,Gui-YingZhang,HongYi,andZhi-QiangXiao.Asubcelluarproteomicinvestigationintovincristine-resistantgastriccancercellline.JournalofCellularBiochemistry.2008，Jun,104(3):1010-21.(SCI影响因子2.935)
(9)Yi-XuanYang,Xue-FengSun,Ai-LanCheng,Gui-YingZhang,HongYi,YiSun,Huai-DongHu,PengHu,FengYe,Zhu-ChuChen,Zhi-QiangXiao.IncreasedexpressionofHSP27linkedtovincristineresistanceinhumangastriccancercellline.JCancerResClinOncol.2009,135(2):181-9.(SCI影响因子2.261)
(10)YIHong，YANGYI-Xuan,CHENZhu-Chu,ZHANGGui-Ying,ZHANGPeng-Fei,LIJian-Ling,ZHUGuo,XIAOZhi-Qiang.Identifacationofmultidrugresistancerelatedproteinsinhumangastriccancercellsusingproteomicstechnique.ProgressinBiochemistryandBiophysics,2006,33(3):267-276.(共同第一作者,SCI影响因子0.193)
(11)SUNYiYIHongYANGYi-XuanZHANGPeng-FeiLIMao-YuLIJian-LingYangFangXIAOZhi-QiangCHENZhu-Chu.IdentificationofProteinsAssociatedWithp53inNasopharyngealCarcinomaCellLineCNE2byProteomicsandRNAiTechniques.ProgressinBiochemistryandBiophysics,2007,34(7):760-769.(SCI影响因子0.193)
(12)ZhangX,XiaoZ,ChenZ,LiC,LiJ,YanhuiY,YangF,YangY,OyangY.Comparativeproteomicsanalysisoftheproteinsassociatedwithlaryngealcarcinoma-relatedgene1.Laryngoscope2006,116(2):224-30.(SCI影响因子2.018)
(13)FengXP,ChenZC,XiaoZQ,YangHY,ZhuGQ,ZhuG,YangYX,LiM,LiC,LiMY,LiF,ZangPF，XiaoJY.OverexpressionofNM23-H1,DJ1andTIM1inpoordifferentialnasopharyngealcarcinomatissuesandCNE2cellline.ProgressinBiochemistryandBiophysics,200532(4)338-346.(SCI影响因子0.193)
(14)YiSun,HongYi,Peng-FeiZhang,Mao-YuLi,CuiLi,FengLi,FangPeng,Xue-PingFeng,Yi-XuanYang,FangYang,Zhi-QiangXiaoandZhu-ChuChen.Identificationofdifferentialproteinsinnasopharyngealcarcinomacellswithp53silencebyproteomeanalysis.FEBSletters,2007,581(1):131-139.(SCI影响因子3.541)
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