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"A Fibril-like Assembly of Oligomers of a Peptide Derived from β-Amyloid" Pham, J. D.; Spencer, R.; Chen, K. H.; Nowick, J. S. J. Am. Chem. Soc. 2014, 136, 12682-12690.
"X-ray Crystallographic Structures of Trimers and Higher-Order Oligomeric Assemblies of a Peptide Derived from Aß17–36" Spencer, R.; Li, H.; Nowick, J. S. J. Am. Chem. Soc. 2014, 136, 5595-5598.
"Polymorphism of Oligomers of a Peptide from β-Amyloid" Pham, J. D.; Demeler, B.; Nowick, J. S. J. Am. Chem. Soc. 2014, 136, 5432-5442. Spotlight in JACS "Finding the Solution: The Structure of Soluble Amyloid Oligomers"
"Mechanism of IAPP Amyloid Fibril Formation Involves an Intermediate with a Transient β-Sheet" Buchanan, L. E.; Dunkelberger, E. B.; Tran, H. Q.; Cheng, P.-N.; Chiu, C.-C.; Cao, P.; Raleigh, D. P.; de Pablo, J. J.; Nowick, J. S.; Zanni, M. T. Proc. Natl. Acad. Sci. U. S. A. 2013, 110, 19285-19290.
"Structures of Oligomers of a Peptide from β-Amyloid" Pham, J. D.; Chim, N.; Goulding, C. W.; Nowick, J. S. J. Am. Chem. Soc. 2013, 135, 12460-12467.
"Recipe for ß-Sheets: Foldamers Containing Amyloidogenic Peptide Sequences" Spencer, R.; Chen, K. H.; Manuel, G.; Nowick, J. S. Eur. J. Org. Chem. 2013, 3523-3528.
"A Hydrophobic Surface is Essential to Inhibit the Aggregation of a Tau-Protein-Derived Hexapeptide" Zheng, J.; Baghkhanian, A. M.; Nowick, J. S. J. Am. Chem. Soc. 2013, 135, 6846-6852.
"The Supramolecular Chemistry of β-Sheets" Cheng, P.-N.; Pham, J. D.; Nowick, J. S. J. Am. Chem. Soc. 2013, 135, 5477–5492.
"Amyloid β-Sheet Mimics that Antagonize Protein Aggregation and Reduce Amyloid Toxicity" Cheng, P.-N.; Liu, C.; Zhao, M.; Eisenberg, D.; Nowick, J. S. Nature Chemistry 2012, 4, 927-933.
"Out-of-Register β-Sheets Suggest a Pathway to Toxic Amyloid Aggregates" Liu, C.; Zhao, M.; Jiang, L.; Cheng, P.-N.; Park, J.; Sawaya,. M. R.; Pensalfini, A.; Gou, D.; Berk, A. J.; Glabe, C. G.; Nowick, J. S.; Eisenberg, D. Proc. Natl. Acad. Sci. U. S. A. 2012, 109, 20913-20918.
"Heterodivalent Linked Macrocyclic β-Sheets with Enhanced Activity against Aβ Aggregation: Two Sites are Better than One." Cheng, P.-N.; Spencer, R.; Woods, R. J.; Glabe, C. G.; Nowick, J. S. J. Am. Chem. Soc. 2012, 133, 14179-14184.
"Giant Macrolactams Based on β-Sheet Peptides" Cheng, P.-N.; Nowick, J. S. J. Org. Chem. 2011, 76, 3166-3173.
"Characteristics of Amyloid-Related Oligomers Revealed by Crystal Structures of Macrocyclic β-Sheet Mimics" Liu, C.; Sawaya, M. R.; Cheng, P.-N.; Zheng, J.; Nowick, J. S.; Eisenberg, D. J. Am. Chem. Soc. 2011, 133, 6736-6744.
"Macrocyclic β-Sheet Peptides that Inhibit the Aggregation of a Tau-Protein-Derived Hexapeptide" Zheng, J.; Liu, C.; Sawaya, M. R.; Vadla, B.; Khan, S.; Woods, R. J.; Eisenberg, D.; Goux, W. J.; Nowick, J. S. J. Am. Chem. Soc. 2011, 133, 3144-3157.
"X-ray Crystallographic Structure of an Artificial β-Sheet Dimer" Khakshoor, O.; Lin, A. J.; Korman, T. P.; Sawaya, M. R.; Tsai, S.-C.; Eisenberg, D.; Nowick, J. S. J. Am. Chem. Soc. 2010, 132, 11622-11628.
"Nanometer-Scale Water-Soluble Macrocycles from Nanometer-Sized Amino Acids" Gothard, C. M.; Nowick, J. S. J. Org. Chem. 2010, 75 1822-1830.
"Use of Disulfide "Staples" To Stabilize β-Sheet Quaternary Structure" Khakshoor, O.; Nowick, J. S. Org. Lett. 2009, 11, 3000-3003.
"A New Artificial β-Sheet that Dimerizes through Parallel β-Sheet Interactions" Levin, S.; Nowick, J. S. Org. Lett. 2009, 11, 1003-1006.
"Exploring β-Sheet Structure and Interactions with Chemical Model Systems" Nowick, J. S. Acc. Chem. Res. 2008, 41, 1319-1330.
"Functionalized Analogues of an Unnatural Amino Acid that Mimics a Tripeptide β-Strand" Khasanova, T. V.; Khakshoor, O.; Nowick, J. S. Org. Lett. 2008, 10, 5293-5296.
"An Artificial β-Sheet That Dimerizes through Parallel β-Sheet Interactions" Levin, S.; Nowick, J. S. J. Am. Chem. Soc. 2007, 129, 13043-13048.
"Nanometer-Sized Amino Acids for the Synthesis of Nanometer-Scale Water-Soluble Molecular Rods of Precise Length" Gothard, C. M.; Rao, N. A.; Nowick, J. S. J. Am. Chem. Soc. 2007, 129, 7272-7273.
"Macrocyclic β-Sheet Peptides that Mimic Protein Quaternary Structure through Intermolecular β-Sheet Interactions" Khakshoor, O.; Demeler, B.; Nowick, J. S. J. Am. Chem. Soc. 2007, 129, 5558-5569.
"Cyclic Modular β-Sheets" Woods, R. J.; Brower, J. O.; Castellanos, E.; Hashemzadeh, M.; Khakshoor, O.; Russu, W. A.; Nowick, J. S. J. Am. Chem. Soc. 2007, 129, 2548-2558.
"A New Class of Macrocyclic Receptors from iota-Peptides" Kang, S.-W. Gothard, C. M.; Maitra, S.; Atia-tul-Wahab; Nowick, J. S. J. Am. Chem. Soc. 2007, 129, 1486-1487.
"What I Have Learned by Using Chemical Model Systems to Study Biomolecular Structure and Interactions" Nowick, J. S. Org. Biomol. Chem. 2006, 4, 3869-3885.
"The Absence of Favorable Aromatic Interactions between β-Sheet Peptides" Chung, D. M.; Dou, Y.; Baldi, P.; Nowick, J. S. J. Am. Chem. Soc. 2005, 127, 9998-9999.
"Enantioselective Molecular Recognition between β-Sheets" Chung, D. M.; Nowick, J. S. J. Am. Chem. Soc. 2004, 126, 3062-3063.
"DSA: A New Internal Standard for NMR Studies in Aqueous Solution", Nowick, J. S.; Khakshoor, O.; Hashemzadeh, M.; Brower, J. O. Org. Lett. 2003, 5, 3511-3513.
"Sequence-Selective Molecular Recognition Between β-Sheets", Nowick, J. S.; Chung, D. M. Angew. Chem., Int. Ed. Engl. 2003, 42, 1765-1768.
"A Ribozyme with Michaelase Activity: Synthesis of the Substrate Precursors" Eisenführ, A.; Arora, P. S.; Sengle, G.; Takaoka, L. R.; Nowick J. S.; Famulok, M. Bioorg. Med. Chem. 2003, 11, 235-249.
"A New Turn Structure for the Formation of β-Hairpins in Peptides", Nowick, J. S.; Brower, J. O. J. Am. Chem. Soc. 2003, 125, 876-877.
"Methylglyoxal Synthetase, enol-Pyruvaldehde, Glutathione, and the Glyoxalase System" Rose, I. A.; Nowick, J. S. J. Am. Chem. Soc. 2002, 124, 13047-13052.