研究领域
酶的分子设计和分子识别
（1）乙酰胆碱酯酶的分子设计、定点突变及分析应用；（2）有机磷水解酶的分子设计、分子模拟及分析应用；（3）老年病相关酶抑制剂的筛选方法学研究。
近期论文
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Yaodong Zhang, Tingting Hei, Yanan Cai, Qunqun Gao, Qi Zhang. Affinity binding-guided fluorescent nanobiosensor for acetylcholinesterase inhibitors via distance modulation between the fluorophore and metallic nanoparticle. Analytical chemistry, 2012, 84 (6), 2830–2836.
Yaodong Zhang, Li Li, Caihong Yu, Tingting Hei. Chitosan-coated polystyrene microplate for covalent immobilization of enzyme. Analytical and bioanalytical chemistry, 2011, 401(7), 2311–2317.
Yaodong Zhang, Yanan Cai, Li Li, Yunxia Qian, Lu Lu High-throughput biosensing of neurotoxic insecticides using polystyrene microplate-immobilized acetylcholinesterase. Analytical method, 2012, 4(11), 3830-3835.
Yaodong Zhang, Yun Zhang, Juanjuan Jiang, Li Li, Caihong Yu, Tingting Hei. Surface derivatization with spacer molecules on glutaraldehyde-activated amino-microplates for covalent immobilization of β-glucosidase. Applied surface science, 2011, 257(7), 2712–2716.
Yaodong Zhang, Bolun Yang. In vivo optimizing of intracellular production of heterologous protein in Pichia Pastoris by fluorescent scanning. Analytical biochemistry. 2006, 357(2), 232–239.
Yaodong Zhang, Susanne Muench, Holger Schulze, Roland Perz, Bolun Yang, Rolf D Schmid, Till T Bachmann. Disposable biosensor test for organophosphate and carbamate insecticides in milk. Journal of Agricultural and Food Chemistry. 2005, 53(13), 5110-5115.
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