研究领域
有机合成方法学;天然产物全合成
(1)有机杂环化合物的重排反应及应用,(2)具有生物活性的复杂天然产物全合成。
近期论文
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Guo, Jiawei; Yu, Binxun*; Wang, Ya-Nan; Duan, Dongyu; Ren, Li-Li; Gao, Ziwei*; Gou, Jing . Conversion of 2-Furylcarbinols with Alkyl or Aryl Azides to Highly Functionalized 1,2,3-Triazoles via Cascade Formal [3 + 2] Cycloaddition/Ring-Opening. Org. Lett., 2014, 16 (19), 5088–5091
Yu, Binxun; Huang, Zheng; Zhang, Min; Dillard, Darren R.; Ji, Haitao*. Rational Design of Small-Molecule Inhibitors For β-Catenin/T-Cell Factor Protein-Protein Interactions. ACS Chem. Biol., 2013, 8 (3), 524–529
Yu, Binxun; Jiang, Tuo; Quan, Weiguo; Li, Junpeng; Pan, Xinfu; She, Xuegong*. An Efficient Method for Construction of the Angularly Fused 6,3,5-Tricyclic Skeleton of Mycorrhizin A and Its Analogues. Org. Lett. 2009, 11(3), 629–632.
Yu, Binxun; Jiang, Tuo.; Li, Junpeng; Pan, Xinfu; She, Xuegong*. A Novel Prins Cyclization through Benzylic/Allylic C−H Activation. Org. Lett. 2009, 11(15), 3442–3445.
Zhang, Min; Huang, Zheng; Yu, Binxun; Ji, Haitao*. New homogeneous high-throughput assays for inhibitors of β-catenin/Tcf protein-protein interactions. Anal Biochem. 2012, 424(1), 57–63.
Sun, Yongquan; Yu, Binxun; Wang, Xiaolei; Tang, Shibing; She*, Xuegong; Pan, Xinfu*. Stereoselective Syntheses of Four Diastereomers of 3,9,12-Trihydroxycalamenene via a Benzobicyclo[3.3.1] Intermediate. J. Org. Chem. 2010, 75(12), 4224–4229.
Zheng, Huaiji; Zheng, Jiyue; Yu, Binxun; Cheng, Qiang; Wang, Xiaolei; He, Yongping; Yang, Zhen; She, Xuegong*. Pt-Catalyzed Tandem 1,2-Acyloxy Migration/Intramolecular [3 + 2] Cycloaddition of Enynyl Esters. J. Am. Chem. Soc. 2010, 132(6), 1788-1789.
Liang, Qiren; Sun, Yongquan; Yu, Binxun; She, Xuegong*; Pan Xinfu*. First Total Syntheses and Spectral Data Corrections of 11-α-Methoxycurvularin and 11-β-Methoxycurvularin. J. Org. Chem. 2007, 72(25), 9846–9849.
Quan, Weiguo; Yu, Binxun; Zhang, Jiyong; Liang, Qiren; She, Xuegong*; Pan Xinfu*. Facile total synthesis of the (L)-Heliconol A. Tetrahedron 2007, 63(40), 9991–9996.
Quan, Weiguo; Yu, Binxun; Zhang, Jiyong; Liang, Qiren; Sun, Yongquan; She, Xuegong*; Pan Xinfu*. A Facile Approach to Synthesis of the Di-O-methyl Ethers of (-)-Agatharesinol, (-)-Sugiresinol, (+)-Nyasol and (+)-Tetrahydronyasol. Chinese Journal of Chemistry 2007, 25(5), 688-693.