研究领域
不对称催化、手性药物合成以及化学生物学研究
1）高效手性配体设计与合成及其不对称催化反应研究；2）手性药物合成及其构效关系研究；3）新型荧光小分子探针的设计与合成；
近期论文
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Zhiyan Huang , Li hui Lim, Zuliang Chen, Yongxin Li, Feng Zhou, Haibin Su, Jianrong (Steve) Zhou.* Arene CH-O Hydrogen Bonding: A Stereocontrolling Tool in Palladium-Catalyzed Arylation and Vinylation of Ketones. Angew. Chem., Int. Ed. 2013, 52, 4906. (Hot paper)
Zhiyan Huang, Zuliang Chen, Li Hui Lim, Gia Chuong Phan Quang, Hajime Hirao, Jianrong (Steve) Zhou.* Weak Arene C-H…O Hydrogen Bonding in Palladium-Catalyzed Arylation and Vinylation of Lactones. Angew. Chem., Int. Ed. 2013, 52, 5807.
Zhiyan Huang, Zheng Liu, Jianrong (Steve) Zhou.* An Enantioselective, Intermolecular α-Arylation of Ester Enolates to Form Tertiary Stereocenters. J. Am. Chem. Soc. 2011, 133, 15882.
One of top 20 most read articles monthly in ACS 2011.
Highlighted by Lautens et al in Synfacts. 2011, 32, 1324.
Hongshan Lai#, Zhiyan Huang#, Qiong Wu, Yong Qin.* Synthesis of Novel Enantiopure Biphenyl P,N-Ligands and Application in Palladium-Catalyzed Asymmetric Addition of Arylboronic Acids to N-Benzylisatin. J. Org. Chem. 2009, 74, 283. (#Two authors contribute equally to this work)
Zhiyan Huang, Hongshan Lai, Yong Qin*, Syntheses of Novel Chiral Sulfinamido Ligands and Their Applications in Diethylzinc Additions to Aldehydes. J. Org. Chem. 2007, 72, 1373.
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