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个人简介

2000年7月于聊城大学化学化工学院获理学学士学位,2003年7月于山东师范大学化学化工与材料科学学院获理学硕士学位,2006年7月于中国科学院生态环境研究中心获理学博士学位,2006年7月至2008年6月在清华大学化学系从事博士后研究。2008年9月进入山东师范大学化学化工与材料科学学院工作。

研究领域

光学功能探针设计、合成及其诊疗应用;细胞及活体成像。

近期论文

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Yong Li, Yingzheng Shu, Xu Wang,* Xiaoyun Jiao, Xilei Xie, Jian Zhang and Bo Tang*, A H2S-activated Ratiometric CO Photoreleaser Enabled by Excimer/Monomer Conversion, Chem. Commun., 2019, accepted, doi: 10.1039/c9cc02352f Jian Zhang, Muwen Liang, Xu Wang,* Yong Li, Xiaoyun Jiao, Xilei Xie, and Bo Tang*, Visualizing Peroxynitrite Fluxes in Myocardial Cells by a New Fluorescent Probe Reveals the Protective Effect of Estrogen, Chem. Commun., 2019, accepted, doi: 10.1039/c9cc02591j Yong Li, Zhiwen Zhao, Yongsheng Xiao, Xu Wang,* Xiaoyun Jiao, Xilei Xie, Jian Zhang and Bo Tang*, Reactivity modulation of benzopyran-coumarin platform by introducing electron-withdrawing groups: specific detection of biothiols and peroxynitrite, Anal. Chem., 2019, 91, 6097-6102 Xilei Xie,*, Guangzhao Liu, Xingxing Su, Yong Li, Yawen Liu, Xiaoyun Jiao, Xu Wang,* and Bo Tang*, A Facile, Versatile, and Highly Efficient Strategy for Peroxynitrite Bioimaging Enabled by Formamide Deformylation, Anal. Chem., 2019, 91, DOI: 10.1021/acs.analchem.9b01175 Xilei Xie, Tianhong Wu, Xu Wang,* Yong Li, Kaiye Wang, Zhiwen Zhao, Xiaoyun Jiao and Bo Tang*, Two-photon fluorescent probe for ratiometric visualization of hypochlorous acid in live cells and animals based on selenide oxidation/elimination tandem reaction, Chem. Commun., 2018, 54, 11965-11968 Yong Li, Yingzheng Shu, Muwen Liang, Xilei Xie, Xiaoyun Jiao, Xu Wang*, and Bo Tang*, A Two-photon H₂O₂-activated CO Photoreleaser, Angew. Chem. Int. Ed., 2018, 57, 12415-12419 Xilei Xie*, Fuyan Tang, Guangzhao Liu, Yong Li, Xingxing Su, Xiaoyun Jiao, Xu Wang*, and Bo Tang*, Mitochondrial Peroxynitrite Mediates Anthracycline Induced Cardiotoxicity as Visualized by a Two-Photon Near-Infrared Fluorescent Probe, Anal. Chem., 2018, 90, 11629-11635 Xiaoyun Jiao, Yongsheng Xiao, Yong Li, Muwen Liang, Xilei Xie, Xu Wang* and Bo Tang*, Evaluating Drug-Induced Liver Injury and Its Remission via Discrimination and Imaging of HClO and H2S with a Two-Photon Fluorescent Probe, Anal. Chem., 2018, 90, 7510-7516 Xiaoyun Jiao, Yong Li, Jinye Niu, Xilei Xie, Xu Wang*, Bo Tang*, Small-Molecule Fluorescent Probes for Imaging and Detection of Reactive Oxygen, Nitrogen, and Sulfur Species in Biological Systems, Anal. Chem., 2018, 90, 533-555 Xilei Xie, Jilin Fan, Muwen Liang, Yong Li, Xiaoyun Jiao, Xu Wang*, Bo Tang*, A two-photon excitable and ratiometric fluorogenic nitric oxide photoreleaser and its biological applications, Chem. Commun., 2017, 53, 11941 -11944 Yong Li, Xilei Xie, Xiu’e Yang, Mengmeng Li, Xiaoyun Jiao, Yuhui Sun, Xu Wang* and Bo Tang*, Two-photon Fluorescent Probe for Revealing Drug-induced Hepatotoxicity via Mapping Fluctuation of Peroxynitrite, Chem. Sci., 2017, 8, 4006-4011 Xilei Xie, Fuyan Tang, Xiaoyan Shangguan, Shiyi Che, Jinye Niu, Yongsheng Xiao, Xu Wang* and Bo Tang*, Two-photon imaging of formaldehyde in live cells and animals utilizing a lysosome-targetable and acidic pH-activatable fluorescent probe. Chem. Commun., 2017, 53, 6520-6523 Jinye Niu, Jilin Fan, Xu Wang*, Yongsheng Xiao, Xilei Xie, Xiaoyun Jiao, Chuan-Zhi Sun, and Bo Tang*, Simultaneous Fluorescence and Chemiluminescence Turned on by Aggregation-Induced Emission for Real-time Monitoring of Endogenous Superoxide Anion in Live Cells. Anal. Chem., 2017, 89, 7210–7215 Xilei Xie, Mengmeng Li, Fuyan Tang, Yong Li, Leilei Zhang, Xiaoyun Jiao, Xu Wang,* and Bo Tang*, Combinatorial Strategy to Identify Fluorescent Probes for Biothiol and Thiophenol Based on Diversified Pyrimidine Moieties and Their Biological Applications, Anal. Chem., 2017, 89, 3015−3020 Xilei Xie, Xiu’e Yang, Tianhong Wu, Yong Li, Mengmeng Li, Qi Tan, Xu Wang*, and Bo Tang*, Rational Design of an α-Ketoamide-Based Near-Infrared Fluorescent ProbeSpecific for Hydrogen Peroxide in Living Systems, Anal. Chem., 2016, 88, 8019-8025 Yong Li,1 Xu Wang,1 Jie Yang, Xilei Xie, Mengmeng Li, Jinye Niu, Lili Tong, and Bo Tang*, Fluorescent Probe Based onAzobenzene-Cyclopalladium for the Selective Imaging of Endogenous CarbonMonoxide under Hypoxia Conditions, Anal. Chem., 2016,88, 11154–11159 QinglingLi, Peilin Chen, Yuanyuan Fan, Xu Wang, Kehua Xu, Lu Li*, and Bo Tang*. Multicolor Fluorescence Detection-Based Microfluidic Device for Single-CellMetabolomics: Simultaneous Quantitation of Multiple Small Molecules in PrimaryLiver Cells, Anal. Chem., 2016, 88, 8610-8616 Hongmin Li, Lu Li, Xu Wang, Qingling Li, Miao Du, Bo Tang*, Dual-calibration coefficient: a more accurate protocol for simultaneous determination of superoxide and hydrogen peroxide in human HepG2 cell extracts, Science China Chemistry, 2015, 58, 825-829 Xu Wang, Jianzheng Lv, Xueying Yao, Yong Li, Fang Huang, Mengmeng Li, Jie Yang, Xiuyun Ruan, Bo Tang*, Screening and investigation of a cyanine fluorescence probe for simultaneous sensing of glutathione and cysteine with single excitation, Chem. Commun., 2014, 50, 15439-15422 Jinye Niu1, Xu Wang1, Jianzheng Lv, Yong Li, Bo Tang*, Luminescent nanoprobes for in-vivo bioimaging, TRAC Trends in Anal. Chem., 2014, 58, 112-119

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