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个人简介

1984年安徽师范大学获理学学士学位 1998年南京师范大学获理学博士学位 1984年-至今,安徽师范大学生命科学学院工作 主要研究课题 ·国家自然科学基金项目,平胸龟线粒体DNA的重复控制区进化及转录组学研究(No.31372198),2014—2017年,主持 ·国家星火计划重点项目子课题,草龟高效安全繁育与养殖技术集成与示范((2013GA710001))。2013—2014年,主持。 ·国家自然科学基金项目,淡水龟科具闭壳结构龟类属间系统发生关系、分歧时间和我国分布物种多样性的研究(No.30970351),2010—2012年,主持 ·教育部博士点专项科研基金,基于线粒体全序列和微卫星标记探讨我国四种龟类物种的有效性(20080370001),2009.1—2011.12年,主持 ·国家自然科学基金,基于微卫星标记和线粒体全序列探讨中华鳖遗传多样性及两近缘物种的有效性(30770296),2008—2010年,主持 ·国家自然科学基金,中华鳖分子系统地理学和两近缘物种有效性的研究(30640048),2007-2008年,主持 ·国家自然科学基金,我国龟鳖目动物分子系统学的研究(30370211),2003-2004年,主持 ·安徽省人力资源厅人才项目,闭壳龟类遗传保护研究,2017-2019年,主持

研究领域

·龟鳖类动物生物多样性及分子系统进化研究 ·两栖爬行动物细胞遗传学及性别决定分子机制和性别人工控制研究 ·医学分子生物学 ·生物化感作用的分子机制

近期论文

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1、代表性论文(20篇以内,*号为通讯作者): · Xiong Lei , Yang Mengli, Zheng Kai, Wang Ziming, Gu Shengli, Tong Jiucui, Liu Jianjun , Nadar Ali Shah and Nie Liuwang. Comparison of Adult Testis and Ovary MicroRNA Expression Profiles in Reeves’ Pond Turtles (Mauremys reevesii) With TemperatureDependent Sex Determination. Frontiers in Genetics. 2020, 11:133. doi: 10.3389/fgene.2020.00133 · Dong Jinxiu; Xiong Lei; Ding Hengwu; Jiang Hui; Zan Jiawei; Nie Liuwang *. Characterization of DNA Methylation and Transcript Abundance of Sex-related Genes during Temperature-dependent Sex Determination in Mauremys reevesii. Biology of Reproduction, 2020, 102(1):27-37 · Liu J.J. Wang M. WANG,Y, Q. Shi,Q. Li J. LI. Wang Y. WANG & Nie LW. Rapid development of novel microsatellite markers from Mauremys reevesii (Testudines: Geoemydidae) using next-generation DNA sequencing technology. The European Zoological Journal. 2019, 316–321. DOI: 10.1080/24750263.2019.1652359 · Dong Jinxiu, Jiang Hui, Xiong Lei, Zan Jiawei, Liu Jianjun, Yang Mengli, Zheng Kai,Wang Ziming, Nie Liuwang*. Detecting coevolution of positively selected in turtles sperm-egg fusion proteins. Mechanisms of Development. 2019, 156:1-7. DOI: 10.1016/j.mod.2019.02.001 · Tong Jiucui, ZhouZ himing, Qi Weiwei, Jiang Siyan, Yang Bin, Zhong Zhengling, Jia Yuanwei, LiX uyi , Xiong Lei, Nie Liuwang,* Antidepressant effect of helicid in chronic unpredictable mild stress model in rats. International Immunopharmacology. 2019. 67:13-21. DOI: 10.1016/j.intimp.2018.11.052 · Xiong Lei, Dong Jinxiu, Jiang Hui, Zan Jiawei, Tong Jiucui, Liu Jianjun, Nie Liuwang*. Transcriptome sequencing and comparative analysis of ovary and testis identify potential key sex-related genes in Mauremys reevesii with temperature-dependent sex determination. PeerJ. 2019. DOI: 10.7717/peerj.6557. · Liu Jianjun, Jiang Hui, Zan Jiawei, Bao Yuantian, Dong Jinxiu, Xiong Lei &, Nie Liuwang *. Single-molecule long read transcriptome profiling of Platysternon megacephalum mitochondrialgenome with gene rearrangement and control region duplication . RNA BIOLOGY. 2018, 15( 9) : 1244-1249 . DOI: 10.1080/15476286.2018.1521212 · Yan Liang, Ma Jinzhu, Zhu Yiping, Zan Jiawei, Wang Zhen, Ling Liefeng, Li Qiang, Lv Jun, Qi Shimei, Cao Yingya, Liu Ying, Cao Long, Zhang Yao, Qi Zhilin, and Nie Liuwang *. miR-24-3p promotes cell migration and proliferation in lung cancer by targeting SOX7. Journal of Cellular Biochemistry. 2018, 119( 5): 3989-3998DOI 10.1002/jcb.26553 · Yan Liang, Ma Jinzhu, Wang Yi, Zan Jiawei, Wang Zhen, Zhu Yu, Zhu Yiping, Ling Liefeng, Cao Long, Liu Xin, Li Shu, Xu Lei, Qi Zhilin, Nie Liuwang* and Zhang Yao*. miR 21 5p induces cell proliferation by targeting TGFBI in non small cell lung cancer cells. EXPERIMENTAL AND THERAPEUTIC MEDICINE. 2018, DOI: 10.3892/etm.2018.6752 · Li Haifeng., Liu Jianjun., Xiong Lei., Zhang Huanhuan., Zhou Huaxin, Yin Huaxin., Li Jun., Shi Qiong., Wang Yuqin., Liu Juanjuan., Nie Liuwang*. Phylogenetic relationships and divergence dates of softshell turtles (Testudines: Trionychidae) inferred from complete mitochondrial genomes. Journal of Evolutionary Biology. 2017, Doi:10.1111/jeb.13070 · Bu Xingjiang*; Jiang Yanmei; Nie Liuwang*; Xia Xingquan. High frequency of multiple paternity in the Chinese soft-shelled turtle. Aquaculture Research, 2017, 48(9): 5155-5158 · Yin Huazong, Nie Liuwang*, Zhao Feifei, Zhou Huaxing, Li Haifeng, Dong Xianmei, Zhang Huanhuan, Wang Yuqin, Shi Qiong and Li Jun. De novo assembly and characterization of the Chinese three-keeled pond turtle (Mauremys reevesii) transcriptome: presence of longevity-related genes. PeerJ. 2016, 4:e2062; DOI 10.7717/peerj.2062(SCI收录) · Zhou Huaxing, Jiang Yuan, Nie Liuwang*, Yin Huazong, Li Haifeng, Dong Xianmei, Zhao Feifei, Zhang Huanhuan, Pu Youguang, Huang Zhenfeng, Song Jiaolian, Sun Entao. The Historical Speciation of Mauremys Sensu Lato: Ancestral Area Reconstruction and Interspecific Gene Flow Level Assessment Provide New Insights. PLoS One, 2015, 10(12): e0144711. doi:10.1371/journal.pone.0144711(SCI收录) · Zheng Chenfei, Nie Liuwang *, Wang Jue, Zhou Huaxing, Hou Huazhen, Wang Hao, Liu Juanjuan. Recombination and Evolution of Duplicate Control Regions in the Mitochondrial Genome of the Asian BigHeaded Turtle, Platysternon megacephalum. PLoS One,2013, 8(12): e82854. doi:10.1371/journal.pone.0082854(SCI收录) · Bu, Xingjiang; Jiang Yanmei; Xia Xingquan, Nie, Liuwang(*). High frequency of multiple paternity in the Chinese soft-shelled turtle , Quaculture Research, 2017, 48(9): 5155~5158 · Li Shu, Hong Yun, Jin Xin, Li Xianwei, Sun Entao, ZhangGenbao, Lu Linming and Nie Liuwang * Agkistrodon acutus-purified protein C activator protects human umbilical vein endothelial cells against H2O2-induced apoptosis. PHARMACEUTICAL BIOLOGY, 2016, http://dx.doi.org/10.1080/13880209.2016.1224259 (SCI收录) · Li Shu, Hong Yun, Jin Xin, Zhang Genbao, Hu Zaichang, Nie Liuwang*. A new Agkistrodon halys venom-purifed protein C activator prevents myocardial fbrosis in diabetic rats. Croat Med J. 2015, 56:439-46 doi: 10.3325/cmj.2015.56.439 (SCI收录) · Sun En-Tao, Li Chao-Pin, Nie Liu-Wang*, Jiang Yu-Xin. The complete mitochondrial genome of the brown leg mite, Aleuroglyphus ovatus (Acari: Sarcoptiformes): evaluation of largest non-coding region and unique tRNAs. Exp Appl Acarol . 2014, 64:141–157. DOI 10.1007/s10493-014-9816-9(ESI、SCI收录) · Sun Entao, Li Chaopin, Li Shu, Gu Shengli, Nie Liuwang*. Complete mitochondrial genome of Caloglyphus berlesei (Acaridae: Astigmata): The first representative of the genus Caloglyphus. Journal of Stored Products Research. 2014. 59: 282e284(ESI、SCI收录) · Bu XJ, Liu L, Nie LW*. Genetic diversity and population differentiation of the Chinese soft-shelled turtle (Pelodiscus sinensis) in three geographical populations. Biochemical Systematics and Ecology, 2014, 54: 279-284(SCI收录) 2、专著: · 刘祥林 聂刘旺主编, 《基因工程》科学出版社,北京,2005年9月 · 安利国主编,杨桂文、聂刘旺副主编,《细胞工程》, 科学出版社,北京,2005年 · 王曼莹主编,聂刘旺等参编,《分子生物学》,科学出版社,北京,2006年7月 · 张锡然等主编,聂刘旺等参编,《分子细胞生物学进展》 南京师大出版社 1996年 · 单祥年主编,聂刘旺等参编 《临床基因诊断》 南京师大出版社 1999年 3、专利: · 发明专利:乌龟血清对人肺癌细胞抑制作用的应用,专利实审号CN108456709A · 发明专利:基于高通量测序筛选的乌龟微卫星DNA标记,实审号CN201710211233.X · 发明专利:中华鳖微卫星DNA标记,授权专利号201010528420.9 · 发明专利:乌龟微卫星DNA标记,授权专利号201110026152.5

学术兼职

·中国遗传学会理事·中国动物学会两栖爬行动物学分会副理事长·教育部高等学校生物科学与工程教学指导委员会委员·安徽省遗传学会副理事长·安徽省动物学会副理事长·安徽省教育学会中学生物学分会第四届理事会理事长

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