个人简介
1996年安徽农业大学经济林专业本科毕业，
1999年中国药科大学药物化学硕士研究生毕业，
2002年中国科学院上海药物所天然产物化学博士毕业。
2002.7-2004.7 上海药物研究所天然药物化学研究室，助理研究员，期间到诺华公司瑞士总部三个月博士后。
2011年3月开始安徽农业大学工作。
研究领域
茶树次生代谢产物与天然产物化学
1、 研究茶树中新颖次生代谢产物及其形成的机制
2、 研究茶叶加工过程中次生代谢产物的变化规律及形成机制
①. 基于LCMS代谢组学研究主要成分发生哪些变化
②. 运用HPLC和UPLC定量变化了多少
③. 运用天然产物研究方法研究变化成哪些新的化合物
④. 运用有机化学反应机理知识阐明主要成分变化和新成分形成的机制
⑤. 茶叶品质发生变化的物质基础
3、 茶叶化合物的神经细胞保护作用及茶叶促智药物的研发
近期论文
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8 Wei Wang, Bi-Ying Zhu, Pu Wang, Peng Zhang, Wei-Wei Deng, Fei-Hua Wu, Chi-Tang Ho, Zheng-Zhu Zhang, Xiao-Chun Wan, Guan-Hu Bao*. Enathiomeric Trimethylallantoin monomers, dimers, and trimethyltriuet: evidence for an Alternative Catabolic Pathway of Caffeine in Tea Plant. Organic Letters. 2019, 21(13), 5147-5151.
7 Jia-Ping Ke, Wen-Ting Dai, Wen-Jun Zheng, Hao-Yue Wu, Fang Hua, Feng-Lin Hu, Gang-Xiu Chu,* Guan-Hu Bao*. Two Pairs of Isomerically New Phenylpropanoidated Epicatechin Gallates with Neuroprotective Effects on H2O2-Injured SH-SY5Y Cells from Zijuan Green Tea and Their Changes in Fresh Tea Leaves Collected from Different Months and Final Product. Journal of Agricultural and Food Chemistry, 2019, 67(17): 4831-4838.
6 Jian Cheng, Fei-Hua Wu, Pu Wang, Jia-Ping ke, Xiao-Chun Wan, Ming-Hua Qiu, Guan-Hu Bao.Flavoalkaloids with pyrrolidinone ring from Chinese ancient cultivated tea Xi-Gui. Journal of Agricultural and Food Chemistry, 2018, 66(30), 7948-7957.
5 Wei Wang, Xing Tang, Fang Hua, Tie-Jun Ling Xiao-Chun Wan, Guan-Hu Bao. Camellimidazole A-C, Three Methylene-bridged Dimeric Imidazole Alkaloids from Keemun Black Tea. Organic Letters. 2018, 20(9), 2672-2675.
4 Xiao Li, Guang-Jin Liu, Wei Zhang, Yv-Long Zhou, Tie-Jun Ling, Xiao-Chun Wan, Guan-Hu Bao.Novel Flavoalkaloids from White Tea with Inhibitory Activity against Formation of Advanced Glycation End Products. Journal of Agricultural and Food Chemistry, 2018, 66, 4621-4629.
3 Wei Wang, Xi-Wen Fu, Xin-Long Dai, Fang Hua, Gang-Xiu Chu, Ming-Jie Chu, Feng-Lin Hu, Tie-Jun Ling, Li-Ping Gao, Zhong-wen Xie, Xiao-Chun Wan, Guan-hu Bao*. Novel acetylcholinesterase inhibitors from Zijuan tea and biosynthetic pathway of caffeoylated catechin in tea plant. Food Chemistry, 2017, 237(23), 1172-1178.
2 Wu-Xia Bai, Chao Wang, Yi-Jun Wang, Wen-Jun Zheng, Wei Wang, Xiao-Chun Wan, Guan-Hu Bao*, Novel Acylated Flavonol Tetraglycoside with Inhibitory Effect on Lipid Accumulation in 3T3-L1 Cells from Lu’an GuaPian Tea and Quantification of Flavonoid Glycosides in Six Major Processing Types of Tea. Journal of agricultural and food chemistry, 2017, 65 (14), 2999-3005.
1 Yun-Fei Zhu, Jing-Jing Chen, Xiao-Ming Ji, Xin Hu, Tie-Jun Ling, Zheng-Zhu Zhang, Guan-Hu Bao*, Xiao-Chun Wan. Changes of major tea polyphenols and production of four new B-ring fission metabolites of catechins from post-fermented Jing-Wei Fu brick tea. Food Chemistry, 2015, 170, 110-117
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