个人简介
吴金节,男,汉族,教授,博士生导师。现任安徽农业大学临床兽医学学科负责人,安徽省现代农业牛羊产业技术体系功能研究室主任、岗位专家,中国畜牧兽医学会家畜内科学分会常务理事及动物毒物学分会理事,华东地区兽医内科学研究会副理事长,一直从事临床兽医学的教学和科研工作及兽医临床实践和技术推广、服务。研究方向为兽医临床诊疗技术、中药制剂及畜禽健康养殖技术,取得多项研究成果和疾病防治新技术。主持国家级及省级等各类科研项目20余项,参加编写全国高等院校统编教材(或著作)15部,发表学术论文100多篇,荣获省级科研成果3项和安徽省教学成果一等奖1项、二等奖各2项,获国家授权发明专利2项。
主要教学经历与成果:
主讲本科生课程:兽医临床诊断学;兽医内科学
主讲研究生课程:临床兽医学研究进展;兽医临床诊疗技术;高级兽医内科学;兽医临床实践
主要教学成果和教材:
1.家畜内科学动态教学系统的形成与应用,安徽省级教学成果一等奖,1998
2.深化人才培养模式改革推进动物医学国家特色专业建设,安徽省教学成果二等奖,2010
3.依托国家质量工程项目,培养动物医学专业“双创”型人才。安徽省教学成果二等奖,2012
4.兽医临床治疗学,北京:中国农业出版社,2002
5.兽医临床鉴别诊断学,北京:中国农业出版社,2008
6.兽医诊断学,北京:高等教育出版社,2010
7.兽医内科学(第四版),北京:中国农业出版社,2010
8.兽医病理学(第二版),北京:中国农业出版社,2012
近期论文
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1.β-Conglycinin-Induced Intestinal Porcine Epithelial Cell Damage via the Nuclear Factor κB/Mitogen-Activated Protein Kinase Signaling Pathway.Journal of Agricultural and Food Chemistry, 2019, 67, 9009−9021
2.Uric acid transporters BCRP and MRP4 involved in chickens uric acid excretion.BMC Veterinary Research,2019,15:180
3.Effects of 7S and 11S on the intestine of weaned piglets after injection and oral administration of soybean antigen protein.Animal Science Journal,2019, 90:393–400
4.Soybean Glycinin- and βConglycinin-Induced Intestinal Damage in
Piglets via the p38/JNK/NF-κB Signaling Pathway.Journal of Agricultural and Food Chemistry,2018,66, 9534−9541
5.Characterization and Comparison of Ochratoxin A-Ovalbumin (OTA-OVA) Conjugation by Three Methods. Journal of Integrative Agriculture, 2014,13(5): 1130-1136
6.Effects of β-conglycinin on growth performance, immunoglobulin and intestinal mucosal morphology in piglets. Archives of Animal Nutrition,2014,68(3):186-195
7.Astragaloside IV enhances immune functions of RAW264.7 cells by activating the NF-κB/MAPK signalling pathway. International Immunopharmacology, 2017, 49:38-49.
8.Andrographolide Inhibits Inflammatory Cytokines Secretion in LPS-Stimulated RAW264.7 Cells through Suppression of NF-κB/MAPK Signaling Pathway. Evidence-Based Complementary and Alternative Medicine, 2017, 2017:1-9.
9.Induction of immune responses and allergic reactions in piglets by injecting glycinin. Italian Journal of Animal Science, 2016, 15(1):166-173.
10.Effects of soybean antigen proteins on intestinal permeability, 5-hydroxytryptamine levels and secretory IgA distribution in the intestine of weaned piglets. Italian Journal of Animal Science, 2016, 15(1):174-180.
11.Allergens and intestinal damage induced by soybean antigen proteins in weaned piglets. Italian Journal of Animal Science, 2016, 15(3):437-44.
12.High Levels of acetoacetate and glucose increase expression of cytokines in bovine hepatocytes, through activation of the NF-κB signaling pathway. Journal of Dairy Research, 2016, 83(1):51-57.
13.Deoxynivalenol induces apoptosis in PC12 cells via the mitochondrial pathway. Environmental Toxicology and Pharmacology, 2016, 43:193-202.
14.Asensitiveimmunochromatographic assay using colloidal gold–antibody probe for rapid detection of fumonisin B1 in corn. Food Additives &Contaminants: Part A, 2016, 33(9):1435-1443.
15.加味四君子汤对脾虚犬生理生化指标及消化吸收功能的影响.西北农林科技大学学报(自然科学版),2019,47(7):15-22,31
16.加味四君子汤对脾虚犬小肠组织形态及EGF 表达的影响.云南农业大学学报(自然科学),2019,34(3):446−452
17.饲喂高蛋白饲粮对雏鹅盲肠微生物菌群的影响.华南农业大学学报, 2019, 40(3): 6-13
18.β-伴大豆球蛋白通过 p38 / JNK MAPK 信号通路引起 IPEC-J2 细胞损伤.浙江农业学报, 2019,31( 2) : 242-249
19.7Sβ-伴大豆球蛋白通过 NF-κB信号通路引起IPEC-J2细胞的炎性反应.畜牧兽医学报, 2019,50(4):870-878
20.高蛋白饲粮致雏鹅痛风的临床病理学研究.华南农业大学学报 ,2019, 40(1): 46-52
21.富硒酵母和枯草芽孢杆菌对湖羊羔羊小肠黏膜形态和直肠菌群的影响.动物营养学报, 2018,30( 11) : 4660-4669
22. NEFA对体外培养奶牛肝细胞氧化还原状态的影响,西北农林科技大学学报(自然科学版),2017,6(45):37-43.
23. 加味四君子汤对仔猪血清免疫因子水平及肠黏膜免疫的影响,西北农林科技大学学报(自然科学版),2017,3(45):75-81.
24. 高温对淮南麻黄鸡血脑屏障的影响,畜牧兽医学报,2017,4(48):769-776.
25. 绿茶粉和绿茶多酚对犬的抗氧化作用,动物营养学报,2017,10(29):3737-3749.
26. 党参多糖对仔猪生长性能、血清细胞因子及肠黏膜分泌型免疫球蛋白A含量的影响,动物营养学报,2017,11(29):4069-4075.
27.仔猪血清大豆抗原蛋白抗体间接ELISA检测方法的建立.西北农林科技大学学报,2014,42(3):17-22
28. 中药提取物对奶牛乳腺上皮细胞增殖及总蛋白含量的影响,西北农林科技大学学报(自然科学版),2015,1(43):14-20.
29. 腺苷酸活化蛋白激酶信号转导通路在奶牛酮病发生和发展过程中的调控机制,动物营养学报,2015,4(28):1035-1041.