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个人简介

2002/09至2006/06,武汉大学,生命科学学院,学士。 2006/09至2011/06,中国科学院上海生命科学研究院,生物化学与细胞生物学研究所,博士。 2011/07至今,中南民族大学,药学院,教师。

研究领域

传统药物治疗肝脏疾病的活性物质与作用机理

近期论文

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1.MeixianXiang,HanwenSu,YajingHu,YunHu,TianmingYang,GuangwenShu,ChemicalcompositionoftotalflavonoidsfromSalviachinensiaBenthandtheirpro-apoptoticeffectonhepatocellularcarcinomacells:potentialrolesofsuppressingcellularNF-kappaBsignaling.FoodandChemicalToxicology,62(2013)420-426. 2.GuangwenShu,XueMi,JianCai,XinlinZhang,WuYin,XinzhouYang,YouLi,LvyiChen,XukunDeng,Brucine,analkaloidfromseedsofStrychnosnux-vomicaLinn.,represseshepatocellularcarcinomacellmigrationandmetastasis:theroleofhypoxiainduciblefactor1pathway.ToxicologyLetters,222(2013)91-101. 3.FufengChen,HuiXiong,JianxiaWang,XinDing,GuangwenShu,ZhinanMei,AntidiabeticeffectoftotalflavonoidsfromSanguisdraxonisintype2diabeticrats.JournalofEthnopharmacology,149(2013)729-736 4.G.uangwenShu,TianmingYang,ChaoyuanWang,HanwenSu,MeixianXiang,GastrodinstimulatesanticancerimmuneresponseandrepressestransplantedH22hepaticascitictumorcellgrowth:InvolvementofNF-kappaBsignalingactivationinCD4+Tcells.ToxicologyandAppliedPharmacology,269(2013)270-279. 5.XiangpeiZhao,GuangwenShu,LvyiChen,XueMi,ZhinanMei,XukunDeng,AflavonoidcomponentfromDocyniadelavayi(Franch.)SchneidrepressestransplantedH22hepatomagrowthandexhibitslowtoxiceffectontumor-bearingmice.FoodandChemicalToxicology,50(2012)3166-3173. 6.XinzhouYang,ChunpingTang,PingZhao,GuangwenShu,ZhinanMei,AntimicrobialconstituentsfromthetubersofBletillaochracea.PlantaMedica,78(2012)606-610. 7.TaoZheng,GuangwenShu,ZhanzhanYang,ShashaMo,YinZhao,ZhinanMei,AntidiabeticeffectoftotalsaponinsfromEntadaphaseoloides(L.)Merr.intype2diabeticrats.JournalofEthnopharmacology,139(2012)814-821. 8.G.uangwenShu,YunnengTang,YiZhou,ChenWang,JianguoSong,Zac1isahistoneacetylation-regulatedNF-kappaBsuppressorthatmediateshistonedeacetylaseinhibitor-inducedapoptosis.CellDeathandDifferentiation,18(2011)1825-1835.

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