当前位置: X-MOL首页全球导师 国内导师 › 杨新洲

个人简介

学习经历 1995.9-1999.7:同济医科大学,获理学学士学位(药学) 1999.9-2002.7:华中科技大学,获医学硕士学位(药物化学) 2002.9-2005.7:中国科学院上海药物研究所,获理学博士学位(有机化学) 工作经历 2005.7-2007.9:中国科学院上海药物研究所,助理研究员 2007.9-2009.1:瑞士巴塞尔大学药学院从事博士后研究工作(合作导师,MatthiasHamburger教授) 2009.1-2010.12:澳大利亚格里菲斯大学Eskitis新药发现研究所,研究员(ResearchFellow)(合作导师,RonaldJQuinn教授,澳大利亚科学与工程院(ATSE)院士) 2010.12-至今:中南民族大学药学院从事教学和科研工作,副教授,教授 获奖情况 杨新洲(1/8),吴宁,顾成刚,卢汝梅,陈少军,赵平,王强,任永申.基于中药及民族药物库和活性导向的新药发现策略及其应用,湖北省科学技术奖(科技进步奖)二等奖,(科技厅授奖公示已通过),2018年12月。 万定荣,杨新洲(2/8),陈科力,葛月宾,聂晶,焦玉,林亲雄,吴绍敏,南方特色民族药资源调查鉴定、质量控制与规范化应用,教育部高等学校科学研究优秀成果奖(科学技术)科技进步奖二等奖,(教育部授奖公示已通过),2018年12月。 万定荣,杨天鸣,杨新洲(3/10),葛月宾,刘新桥,林亲雄,帅丽,付海燕,陈科力,陈家春.湖北省土家族药材资源、鉴定和质量控制研究,国家民族医药科学技术奖(自然科学奖)二等奖,2014年11月24日。 荣誉 ●2011年入选湖北省新世纪高层次人才第三层次 ●2012年入选湖北省“楚天学者”人才计划(楚天学子) ●2014年入选第7批武汉市东湖高新3551人才计划 ●2013年中南民族大学大学生创新创业项目优秀指导老师 ●2013年汪超,硕士研究生国家奖学金(指导老师) ●2014年杨静,硕士研究生国家奖学金(指导老师) ●2014年第七届全国大学生药苑论坛三等奖(指导老师) ●2014年研究生汪超入选2014年国家建设高水平大学公派博士研究生项目(澳大利亚Griffith大学) ●2015年汪超,湖北省优秀硕士论文(指导老师) ●2015年中南民族大学优秀网络辅助教学二等奖 ●2016年黄密,硕士研究生国家奖学金(指导老师) ●2016年中南民族大学“十佳青年教工” ●2016年教育部审核评估先进个人 ●2017年段欢,湖北省优秀学士论文(指导老师) ●2017年柯蕊芳,第五届全国医药院校药学/中药学专业大学生实验技能大赛一等奖(指导老师) ●2017年陈丽,五届全国医药院校药学/中药学专业大学生实验技能大赛三等奖(指导老师) ●2017年研究生黄密入选2017年国家建设高水平大学公派博士研究生项目(瑞典Lund大学) ●2017年邓世豪,硕士研究生国家奖学金(指导老师) ●2018年黄蕴,硕士研究生国家奖学金(指导老师) 承担的项目(中南民族大学) 1.民族药石上柏作用于喉癌COX-2和EGFR多靶标的活性成分及作用机制研究(国家自然科学基金面上项目81774000),2018.1-2021.12,66万,主持,在研 2.基于GLUT4和SGLT2双靶点的槐属药用植物抗糖尿药效物质基础及作用机制研究(国家自然科学基金面上项目81573561),2016.1-2019.12,66万元,主持,在研 3.基于GLUT4靶点的苦参抗糖尿病活性物质和作用机制研究(国家自然科学基金青年项目81102798),2012.1-2014.12,22万,主持,结题 4.武汉市应用基础研究项目“中药五类新药竹黄降糖有效部位药效学研究”(2017060201010217),2017.8-2019.12,15万,主持,在研 5.新药中药六类川七镇脑宁胶囊开发研究(武汉市国家东湖高新区3551光谷创新人才计划项目BX219),2014.5-2017.5,100万(企业配套400万),主持,结题 6.基于GLUT4靶点的广豆根抗糖尿病活性物质和作用机制研究(中科院上海药物药物研究所新药研究国家重点实验室开放基金SIMM1403KF-07),2014.4-2015.4,8万,主持,结题 7.苦参抗糖尿病有效部位临床前药效和作用机制研究(武汉市科技计划项目青年晨光计划项目2013070104010028),2013.1-2014.12,10万,主持,结题 8.基于GLUT4靶点的苦参抗糖尿病活性物质和作用机制研究(人事部留学回国人员择优资助项目BZY12006),2012.1-2014.12,3万,主持,结题 9.基于GLUT4靶点的苦参抗糖尿病活性物质和作用机制研究(中南民族大学人才引进基金项目YZ211002),2011.1-2013.12,90万,主持,结题 10.中药和民族药物中活性成分快速发现的新技术及在中药新药研发中的应用(中央高校基本科研业务费专项资金资助项目CZP17060,奖项培育),2017.7-2018.7,5万,主持,结题 11.藏药马先蒿质量标准研究(中央高校基本科研业务费专项资金资助项目3212014CZW14051),2013.5-2015.5,5.5万,主持,结题 12.基于土家药物库和GLUT4靶点的抗糖尿病活性成分发现策略(湖北省民族药物现代化工程技术研究中心开放课题2015ZD004),2015.5-2017.4,6万,主持,结题 13.基于壮、傣、土家等民族医特色病种药物的有效性及质量评价关键技术研究(十二五国家科技支撑计划项目2012BAI27B06),2011.1-2015.12,分配经费40万,科研骨干人员,结题 14.藏药预分离组分库建立与抗肝癌活性研究(青海省自然科学基金重点项目2012-Z-904),2012.1-2014.12,分配经费10万,排名第二,结题 15.基于Caspase3靶点和预分离组分库的藏药抗肝癌药效物质及其作用机制研究(青海省自然科学基金重点项目2016-ZJ-908),2016.1-2018.12,分配经费15万,排名第二,结题 16.傣药榼藤子皂苷类成分的抗二型糖尿病活性和药理研究(湖北省自然科学基金一般项目BZY11061),2013.1-2014.12,3万,排名第四,结题 17.基于民族药物预分离组分库的抗前列腺癌的先导化合物发现策略(中南民族大学学生科研基金重点项目KYCX110009E),2012.5-2013.5年,0.6万,指导老师,结题 18.民族药物内生菌抗癌活性成分的发现(国家级大学生创新项目GXX14211),2013.4-2014.4,2万,指导老师,结题 19.苦参降糖活性部位毒理学研究(湖北省大学生创新项目SCX15006),2014.4-2015.4,1万,指导老师,结题 20.基于GLUT4靶点的苦豆子抗糖尿病活性物质和作用机制研究(湖北省大学生创新项目SCX15025),2015.4-2016.4,1万,指导老师,结题 21.喜树内生真菌中抗肝癌活性化合物的发现(国家级大学生创新项目GCX1728),2017.4-2018.4,2万,指导老师,结题 以前参与的项目 1.新型促智化合物的发现和促智化合物作用机制的研究(国家自然科学基金面上项目30123005),2002.1-2004.12,主要参与人 2.后基因组时代新药发现关键技术研究(上海市自然科学基金重点项目036505003),2003.1-2005.12,主要参与人 3.建立来源于传统中草药的天然产物库(中科院上海药物研究所-诺华公司国际合作项目),2002-2008,参与人 4.DiscoveringofGABAAreceptormodulatorsfrommedicinalplantsandfungalmaterials(瑞士国家自然基金项目),2005-2008,主要参与人 5.DiscoveringofanticancerleadsfrommedicinalplantsandfungalmaterialsbasedonHPLCfractionationextractlibrary(瑞士国家自然基金项目),2006-2009,主要参与人 6.DiscoverynewAntimalarialleadfromnaturebank(MedicinesforMalariaVenture慈善基金项目),2008-2010,参与人 7.辉瑞工业合作项目“PfizerCollaboration-Anti-InfectiveProject”,2009-2011,主要参与人

研究领域

天然来源(中药、民族药、微生物)的先导化合物发现

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

1.RenZhang,JiHao,KaiwenGuo,WanxinLiu,FeiYao,QingmingWu,ChangLiu,QiangWang*,XinzhouYang*.EssentialoilofSaussureacostusinducesapoptosisbyactivatingmitochondrialpathwayandERstress,andinhibitingSTAT3inHumanEsophagealSquamousCellCarcinomaCells.InternationalJournalofMolecularSciences,2019,revised. 2.ChangLiu,HongLiu,YanzhangWen,HuiqiHuang,JiHao,YibingLv,RuiQin*,XinzhouYang*.AspernolideAinhibitsproliferationofhumanlaryngealcarcinomacellsthroughthemitochondrialapoptoticandSTAT3signalingpathways.Molecules,2019,submitted. 3.HaoChen,JiHao,YibinLv,YunHuang,JingquanYuan*,XinzhouYang*.α-HumuleneinduceshepatocellularcarcinomacellantiproliferationandapoptosisthroughinhibitingAKTsignaling.PharmacologicalResearch,2018,submitted.(中科院2区,IF4.90) 4.KejianPang,ShihaoDeng,HaoChen,YanzhangWen,JiHao,YunHuang,YibingLv,XinzhouYang*.Twonewcompoundsfromapolyphenol-richextractofPhellinusigniarius.NaturalProductResearch,2019,submitted.(1co-firstauthors,中科院4区,IF1.83) 5.GuanjunSong1,YunHuang1,MingruiXiong,DiTian,Qing-HuaLiu,JinhuaShen,PingZhao*,XinzhouYang*.Aloperinerelievestype2diabetesmellitusviaenhancingGLUT4expressionandtranslocation.JournalofBiologicalChemistry,2019,revised.(1co-firstauthors,中科院2区,IF4.01,Top) 6.PingZhao*,DiTian,GuanjunSong,QianMing,JiaLiu,JinhuaShen,Qing-HuaLiu,XinzhouYang*.NeferineenhancesGLUT4expressionandfusionwithplasmamembranetopromoteglucoseuptakeinL6cells.Food&Function,2019,submitted.(中科院1区,IF3.29) 7.PingSong,HaoChen,YunHuang,YanzhanWeng,YibingLv,ShihaoDeng*,XinzhouYang*.IsolationandstructureelucidationofphenolicacidsfromtheseedsofSophoraalopecuroidesL.ChemistryofNaturalCompounds,2019,inpress.(中科院4区,IF0.46) 8.DanLv,JieYang,ChanXu,MiHuang,SijianZheng,XinhuaMa,QiangWang*,XinzhouYang*.EssentialoilfromEuphorbiaesulainhibitsproliferationandinducesapoptosisinHepG2cellsviamitochondrialreactiveoxygenspecies.BrazilianJournalofPharmaceuticalSciences,2019,inpress.(中科院4区,IF0.90) 9.YanzhangWen,YibingLv,JiHao,HaoChen,YunHuang,ChangLiu,HuiqiHuang,YuanrenMa,XinzhouYang*.TwonewcompoundsofPenicilliumpolonicum,anendophyticfungusfromCamptothecaacuminataDecne.NaturalProductResearch,2019,https://doi.org/10.1080/14786419.2019.1569003.(中科院4区,IF1.83) 10.YibingLv,QianMing,JiHao,YunHuang,HaoChen,QiangWang,XinzhouYang*,PingZhao*.Anti-diabeticactivityofcanophyllolfromCratoxylumcochinchinense(Lour.)Blumeintype2diabetesmiceviaactivationofAMP-activatedkinaseandregulationofPPARγ.Food&Function,2019,10:964-977.(中科院1区,IF3.47) 2018 11.QiangWang,LihongPan,LiLin,RenZhang,YuchaoDu,HaoChen,MiHuang,KaiwenGuo*,XinzhouYang*.EssentialoilfromCarpesiumabrotanoidesL.inducesapoptosisviaactivatingmitochondrialpathwayinhepatocellularaarcinomacells.CurrentMedicalScience,2018,38(6):1045-1053.(JCRQ4,IF0.96) 12.PingZhao*,QianMing,JunyingQiu,DiTian,JiaLiu,JinhuaShen,QinghuaLiu,XinzhouYang*.EthanolicextractofFoliumSennaemediatestheglucoseuptakeofL6cellsbyGLUT4andCa2+.Molecules,2018,372574.(中科院3,IF3.10) 13.YunHuang,JiHao,DiTian,YanzhangWen,PingZhao,HaoChen,YibinLv,XinzhouYang*.Antidiabeticactivityofaflavonoid-richextractfromSophoradavidi(Franch.)skeelsinKK-AymiceviaactivationofAMP-activatedproteinkinase.FrontiersinPharmacology,2018,9:760.doi:10.3389/fphar.2018.00760.(中科院2区,IF3.86) 14.GuangwenShu,JiHao,WeiLi,LangZhang,YunhanQiu,XinzhouYang*.LiensininesuppressesSTAT3-dependentHK2expressionthroughelevatingSHP-1toinduceapoptosisinhepatocellularcarcinomacellsinvitroandinvivo.JournalofFunctionalFoods,2018,45:288-297.(中科院2区,IF3.14) 15.PingZhao*,QianMing,MingruiXiong,GuanjunSong,LiTan,DiTian,JiaLiu,ZhaoHuang,JingyiMa,JinhuaShen,Qing-HuaLiu,XinzhouYang*.DandelionchloroformextractpromotesglucoseuptakeviatheAMPK/GLUT4pathwayinL6cells.Evidence-BasedComplementaryandAlternativeMedicine,2018,1709587.https://doi.org/10.1155/2018/1709587.(中科院4区,IF1.74) 16.PingSong,HaoChen,XinhuaMa,JieYang,YunHuang,YanzhangWen,YibingLv,ShihaoDeng*,XinzhouYang*.CytotoxiccompoundsfromtheseedsofSophoraalopecuroidesL.NaturalProductCommunications,2018,13(8),997-1000.(中科院4区,IF0.89) 17.MingruiXiong1,YunHuang1,YajingLiu,MiHuang,GuanjunSong,QianMing,XinhuaMa,JieYang,ShihaoDeng,YanzhangWen,JinhuaShen,Qing-HuaLiu,PingZhao*,XinzhouYang*.AntidiabeticactivityofergosterolfromPleurotusostreatusinKK-Aymicewithspontaneoustype2diabetesmellitus.MolecularNutrition&FoodResearch,2018,62(3).doi:10.1002/mnfr.201700444.(1co-firstauthors,中科院1区,Top,IF5.15) 18.SijianZheng1,ShihaoDeng1,MiHuang,PingZhao,YunHuang,XinhuaMa,YanzhangWen,QiangWang*,XinzhouYang*.Anti-diabeticactivityofpolyphenol-richextractfromPhellinusigniariusinKK-Aymicewithspontaneoustype2diabetesmellitus.Food&Function,2018,9:614-623.(1co-firstauthors,中科院1区,IF3.25) 19.JieYang1,HaoChen1,ShihaoDeng,MiHuang,XinhuaMa,PingSong,JingwenDu,YunHuang,YanzhangWen,YongshenRen*,XinzhouYang*.Inhibitoryeffectofkurarinoneongrowthofhumannon-smallcelllungcancer:anexperimentalstudybothinvitroandinvivostudies.FrontiersinPharmacology,2018,9:252.https://doi.org/10.3389/fphar.2018.00252.(1co-firstauthors,中科院2区,IF3.83) 20.HaoChen1,BeiZhou1,JieYang,XinhuaMa,ShihaoDeng,YunHuang,YanzhangWen,JingquanYuan*,XinzhouYang*.EssentialoilderivedfromEupatoriumadenophorumSpreng.mediatesanticancereffectbyinhibitingSTAT3andAKTactivationtoinduceapoptosisinhepatocellularcarcinoma.FrontiersinPharmacology,2018,9:483.https://doi.org/10.3389/fphar.2018.00483.(1co-firstauthors,中科院2区,IF3.83) 21.LiChen,XinhuaMa,ShihaoDeng,XinzhouYang*,PingSong*.Crystalstructureof6,7-dehydroroyleanoneisolatedfromTaxodiumdistichum(L.)Rich.ActaCrystallographicaSectionE:CrystallographicCommunications,2018,74(Pt1):62. 22.杨洁,文琰章,麻新华,邓世豪,黄蕴,林亲雄,万定荣,杨新洲*,宋萍*.佛甲草中细胞毒活性成分的研究.华中师范大学学报(自科版),2018,52(3):347-354. 23.文琰章,吕静南,陈豪,郝吉,麻新华,黄密,杨洁,杨新洲*,林亲雄*.矮坨坨共生菌Fusariumoxysporum活性代谢产物研究.华中师范大学学报(自科版),2018,52(5):686-693. 24.吴宁,黄密,黄蕴,陈豪,文琰章,郝吉,杨新洲*.基于GLUT4靶点的抗糖尿病中药研究进展.中国药师,2018,21(12):2201-2205. 2017 25.XinzhouYang1,MiHuang1,JieYang,JialinWang,SijianZheng,XinhuaMa,JinyanCai,ShihaoDeng,GunagwenShu*,GuangzhongYang*.Activityofisoliensinineinimprovingthesymptomsoftype2diabeticmiceviaactivationofAMP-activatedkinaseandregulationofPPARγ.J.Agric.FoodChem.,2017,65(33):7168-7178.(1Co-firstauthor,中科院1区,IF3.15) 26.JialinWang1,MiHuang1,JieYang,XinhuaMa,SijianZheng,ShihaoDeng,YunHuang,YanzhangWen,XinzhouYang*,PingZhao*.Anti-diabeticactivityofstigmasterolfromsoybeanoilbytargetingGLUT4glucosetransporter.Food&NutritionResearch,2017,61(1):1364117.(1Co-firstauthor,中科院2区,IF2.04) 27.LiChen1,SijianZheng1,MiHuang1,XinhuaMa,JieYang,ShihaoDeng,YunHuang,YanzhangWen,XinzhouYang*.β-EcdysteronefromCyanotisarachnoideaexertshypoglycemiceffectsthroughactivatingIRS-1/Akt/GLUT4andIRS-1/Akt/GLUT2signalpathwaysinKK-Aymice.JournalofFunctionalFoods,2017,39:123-132.(1Co-firstauthor,中科院2区,IF3.144) 28.YanHu*,HaoChen,MaZuo,XinzhouYang,DanZhao,SuyingZeng,XincaiXiao*.Naturalmaterial-decoratedmesoporoussilicananoparticlescontainerformultifunctionalmembrane-controlledtargeteddrugdelivery.InternationalJournalofNanomedicine,2017,12:8411-8426.(中科院2区,IF4.47) 29.XinzhouYang1,ShihaoDeng1,MiHuang,JialinWang,LiChen,MingruiXiong,JieYang,SijianZheng,XinhuaMa,PingZhao*,YunjiangFeng*.ChemicalconstituentsfromSophoratonkinensisandtheirglucosetransporter4translocationactivities.Bioorg.Med.Chem.Lett.,2017,27(6):1463-1466.(1co-firstauthors,中科院3区,IF2.45) 30.XinhuaMa1,JieYang1,ChristopherL.Brownb,ChaoWang,ShihaoDeng,RuifangKe,ShichengXu,MiHuang,XinzhouYang*,YunjiangFeng*.CytotoxicneolignansfromDaphniphyllummacropodumMiq.RSCAdvances,2017,7:52970-52976.(1Co-firstauthor,中科院3区,IF3.11) 31.JieYang1,ChanXu1,HaoChen,MiHuang,XinhuaMa,ShihaoDeng,YunHuang,YanzhangWen,XinzhouYang*,PingSong*.InvitroandinvivoantitumoreffectsofthediterpeneenrichingextractfromTaxodiumascendensthroughthemitochondrial-dependentapoptosispathway.Biomedicine&Pharmacotherapy,2017,96:1199-1208.(1Co-firstauthor,中科院3区,IF2.76) 32.XinzhouYang1,MiHuang1,JinyanCai,DanLv,JingnanLv,SijianZheng,XinhuaMa,PingZhao*,QiangWang*.Chemicalprofilingofanti-hepatocellularcarcinomaconstituentsfromCaraganatanguticaMaxim.byoff-linesemi-preparativeHPLC-NMR.Nat.Prod.Res.,2017,31(10):1150-1155.(1co-firstauthors,中科院4区,IF1.83) 33.XinhuaMa,JieYang,ShihaoDeng,MiHuang,SijianZheng,ShichengXu,JinyanCai,XinzhouYang*,HonglianAi*.TwonewmegastigmanesfromChinesetraditionalmedicinalplantSedumsarmentosum.Nat.Prod.Res.,2017,31(13):1473-1477.(中科院4区,IF1.83) 34.DanLv1,Kai-wenGuo1,ChanXu,MiHuang,Si-jianZheng,Xin-huaMa,Li-hongPan,QiangWang*,Xin-zhouYang*.EssentialoilfromSiegesbeckiapubescensinducesapoptosisthroughthemitochondrialpathwayinhumanHepG2cells.J.HuazhongUniv.Sci.Technol.Med.Sci.2017,37(1):87-92.(1Co-firstauthor,中科院4区,IF0.96) 35.ShoufangKe,ShichengXu,PingSong,XinhuaMa*,XinzhouYang*.CrystalstructureoftaxodioneisolatedfromTaxodiumascendens(B.).ActaCrystallographicaSectionE,2017,E73,1102-1104. 36.ShichengXu,XinhuaMa,RuifangKe,ShihaoDeng,XinzhouYang*andPingSong*.Crystalstructureof7β-hydroxyroyleanoneisolatedfromTaxodiumascendens(B.).ActaCrystallographicaSectionE,2017,E73,1414-1416. 37.麻新华,黄密,杨洁,柯蕊芳,宋萍,杨新洲*.多穗金粟兰的化学成分及生物活性研究.云南大学学报(自科版),2017,39(1),124-129. 38.郑思建,徐婵,杨洁,黄蕴,文琰章,宋萍,林亲雄,王强,杨新洲*.藏药抗肝癌活性研究.华中师范大学学报(自科版),2017,51(3),328-334. 39.赵平*,熊明瑞,杨新洲,张学智,李妍清.调节GLUT4转位化合物及相关的信号通路研究进展.生命的化学,2017,37,1-6. 2016 40.QiZhou1,XinzhouYang1,MingruiXiong,XiaolanXu,LiZhen,WeiweiChen,YanWang,JinhuaShen,PingZhao*,Qing-HuaLiu*.ChloroquineincreasesglucoseuptakeviaenhancingGLUT4translocationandfusionwiththeplasmamembraneinL6cells.Cell.Physiol.Biochem.2016,38:2030-2040.(1co-firstauthor,中科院2区,IF5.10) 41.GuangwenShu,LangZhang,ShanqingJiang,ZhuoCheng,GuanWang,XuHuang,XinzhouYang*.IsoliensinineinducesdephosphorylationofNF-kBp65subunitatSer536viaaPP2A-dependentmechanisminhepatocellularcarcinomacells:rolesofimpairingPP2A/I2PP2Ainteraction.Oncotarget,2016,7(26):40285-40296.doi:10.18632/oncotarget.9603.(中科院2区,IF5.16) 42.MiHuang,ShihaoDeng,QianqianHan,PingZhao,QiZhou,SijianZheng,XinhuaMa,ChanXu,JingYang,XinzhouYang*.HypoglycemicactivityandthepotentialmechanismoftheflavonoidrichextractfromSophoratonkinensisGagnep.inKK-Aymice.FrontiersinPharmacol.,2016,;7:288.doi:10.3389/fphar.2016.00288.(中科院2区,IF4.40) 43.ChaoWang,XinzhouYang,GeorgeMellick*,YunjiangFeng*.Meetthechallenge:probingParkinson’sdiseasebiologybyintegratedmultidisciplinarymethodology.ACSChemicalNeuroscience,2016,7(12):1628–1634.(中科院2区,IF3.88) 44.XinzhouYang*,MiHuang,SijianZheng,XinhuaMa,DingrongWan,YunjiangFeng*.LiquidchromatographywithmassspectrometryandNMRspectroscopybaseddiscoveryofcytotoxicprinciplesfromDaphnetanguticaMaxim.J.Sep.Sci.,2016,39(11):2179-2187.(中科院3区,IF2.56) 45.MiHuang,PingZhao,MingruiXiong,QiZhou,SijianZheng,XinhuaMa,ChanXu,JingYang,XinzhouYang*,Tong-CunZhang*.Antidiabeticactivityofperylenequinonoid-richextractfromShiraiabambusicolainKK-Aymicewithspontaneoustype2diabetesmellitus.J.Ethnopharmacol.,2016,191:71-81.(中科院3区,IF2.98) 46.KarrenD.Beattie,NicolaEllwood,RohiteshKumar,XinzhouYang,PeterC.Healy,VanidaChoomuenwai,RonaldJ.Quinn,AlyshaG.Elliott,JohnnyX.Huang,JessicaL.Chitty,JamesA.Fraser,MatthewA.Cooper,RohanA.Davis*.AntibacterialandantifungalscreeningofnaturalproductssourcedfromAustralianfungiandcharacterisationofpestalactamsD-F.Phytochemistry,2016,124:79-85.(中科院3区,IF3.21) 47.XinzhouYang,JingYang,ChanXu,JingnanLV,ChaoWang*,PingSong*.AntimicrobialstilbenoidsfromBletillayunnanensisSchltr.Chem.Nat.Comp.,2016,52(1),19-22.(中科院4区,IF0.46) 48.杨新洲,徐婵,黄密,郑思建,麻新华,宋萍,万定荣*.佛甲草细胞毒活性成分研究.云南大学学报(自然科学版),2016,38(1),127-132. 49.杨新洲,吕静南,郝吉,黄密,徐婵,林亲雄*.昆虫共生菌FusariumoxysporumBM2的代谢产物及其抗肝癌活性研究.中南民族大学学报(自科版),2016,35(3),42-47. 50.黄琪佳,吴敏,黄玉莹,廖矛川,杨光忠,林亲雄*,杨新洲*.鸢尾内生真菌FusariumoxysporumYW1的分离鉴定及其次生代谢产物的研究.华中师范大学学报(自科版),2016,50(6),880-885. 51.杨会祥,邓园园,李薇,吕静南,徐婵,马云瑞,杨新洲,林亲雄*.昆虫内生真菌ChaetomiumglobosumZWC5的分离鉴定及其抗癌活性代谢产物的研究.湖南师范大学自然科学学报,2016,39(4),17-22. 2015 52.GuangwenShu,LingYue,WenhaoZhao,ChanXu,JingYang,ShaobingWang,XinzhouYang*.Isoliensinine,abioactivealkaloidderivedfromembryosofNelumbonucifera,induceshepatocellularcarcinomacellapoptosisthroughsuppressionofNF-κBsignaling.J.Agric.FoodChem.,2015,63(40):8793-8803.(中科院1区,IF3.15) 53.XinzhouYang1,JingYang1,ChanXu,MiHuang,QiZhou,JingnanLv,XinhuaMa,ChangqiangKe,YangYe,GuangwenShu*,PingZhao*.AntidiabeticeffectsofflavonoidsfromSophoraflavescensEtOAcextractinType2diabeticKK-Aymice.J.Ethnopharmacol.,2015,171:161-170.(1co-firstauthor,中科院3区,IF2.98) 54.JingYang,XinzhouYang*,ChaoWang,QinxiongLin,ZhinanMei,PingZhao*.Sodium-glucoselinkedtransporter2inhibitorsfromSophoraflavescens.Med.Chem.Res.,2015,24,1265-1271.(中科院4区,IF1.28) 55.PingSong1,QiangWang1,JingnanLv,ChanXu,QinxiongLin,XinhuaMa,MiHuang,XinzhouYang*.HPLC-basedactivityprofilingofanti-Hepatocellularcarcinomaconstituentsfromthetibetanmedicine,Caraganatibetica.J.HuazhongUniv.Sci.Tech.Med.Sci.,2015,35(3):450-455.(1Co-firstauthor,中科院4区,IF0.96) 56.ZuoCheng,LingYue,WenhaoZhao,XinzhouYang,GuangwenShu*.ProtectiveeffectsofprotostemonineonLPS/GalN-inducedacuteliverfailure:Rolesofincreasedhepaticexpressionofhemeoxygenase-1.InternationalImmunopharmacology,2015,29,798-807.(中科院3区,IF2.956) 57.宋萍,徐婵,马云瑞,吕静南,杨静,汪超,杨新洲*.100种常用藏药抗肝癌的体外活性筛选.中南民族大学学报(自科版),2015,34(2),64-67. 58.杨新洲,吕静南,徐婵,林亲雄,杨静,汪超,宋萍*.鬼箭锦鸡儿细胞毒活性成分研究.云南大学学报(自科版),2015,37(1),134-139. 59.徐婵,吴潇潇,万定荣,王强,林亲雄,杨静,吕静南,杨新洲*.三颗针抗菌活性成分研究.华中科技大学学报(医学版),2015,44(5),556-562. 60.赵平,胡松林,杨新洲,马立群.高校动物学理论课教学改革与实践.现代农业科技,2015,9,343,349. 61.杨新洲,林亲雄,万定荣,杨光忠.民族高校天然药物化学实践教学改革探索.广州化工,2015,43(14),252-254. 62.杨新洲,林亲雄,万定荣,杨光忠.民族高校天然药物化学教学改革探索.关爱明天,2015,3,14-15. 2014 63.GuangwenShu,JingYang,ChanXu,ZhinnanMei,XinzhouYang*.Kurarinolinduceshepatocellularcarcinomacellapoptosisthroughsuppressingcellularsignaltransducerandactivatoroftranscription3signaling.ToxicologyandAppliedPharmacology,2014,281(2):157-65.(中科院2区,IF3.79) 64.RohanDavis,KarrenBeattie,MinXu,XinzhouYang,ShengYin,HarishHola,PeterHealy,MelissaSykes,ToddShelper,VickyAvery,MikaelElofsson,CharlottaSundin,RonaldJQuinn*.SolvingthesupplyofresveratroltetramersfromPapuaNewGuineanrainforestAnisopteraspecies(Dipterocarpaceae)thatinhibitbacterialtypeIIIsecretionsystems.J.Nat.Prod.,2014,77(12):2633-2640.(中科院2区,IF3.28) 65.ChaoWang,JingYang,PingZhao,QiZhou,ZhinanMei,GuangzhongYang,XinzhouYang*,YunjiangFeng*.ChemicalconstituentsfromEucalyptuscitriodoraHookleavesandtheirglucosetransporter4translocationactivities.Bioorg.Med.Chem.Lett.,2014,24(14):3096-3099.(中科院3区,IF2.54) 66.XinzhouYang1,ChaoWang1,DingrongWan,QinxiongLin,GuangzhongYang,ZhinanMei*,YunjiangFeng*.AntimicrobialsesquiterpenesfromtheChinesemedicinalplant,Chloranthusangustifolius.TetrahedronLetters,2014,55(41):5632-5634.(中科院3区,IF2.19) 67.HuiXiong,XinDing,XinhzouYang,GuangzhongYang,ZhinanMei.TriterpenesaponinsfromthestemsofEntadaphaseoloides.PlantaMed.,2014,80(8-9):710-718. 68.JingYang,PingZhao,QiZhou,ChaoWang,DingrongWan,GuangwenShu,ZhinanMei,XinzhouYang*.AntidiabeticeffectofmethanolicextractfromBerberisjulianaeSchneid.viaactivationofAMPactivatedproteinkinaseintype2diabeticmice.Evidence-BasedComplementaryandAlternativeMedicine,2014,106206,http://dx.doi.org/10.1155/2014/106206.(中科院4区,IF1.74) 69.ChaoWang,JingYang,ZhinanMei,XinzhouYang*.AcridonealkaloidswithcytotoxicandantimalarialactivitiesfromZanthoxylumsimullansHance.Pharmacog.Mag.,2014,10(37),73-76.(中科院4区,IF1.07) 70.赵平,周琦,毕龙俊,沈金花,杨新洲*,刘庆华*.脂肪细胞中Munc18c的缺失不影响胰岛素诱导的GLUT4转运.生物化学与生物物理进展,2014,41(11):1144-1154.(中科院4区,IF0.34) 71.JingquanYuan,TongLi,ZhinanMei,JiaomeiJiang,YaqinZhou,ZhigangYan,JianhuaMiao,XinzhouYang*,XiaojunMa*.ChemistryandBiologicalActivitiesofHuperziaSerrata.CurrentOpinionComplementAlternativeMedicine,2014,1(2),1-11. 72.杨新洲,杨静,汪超,万近福,袁经权,任永申.苦参中钠-葡萄糖协同转运蛋白2抑制活性成分的研究.云南大学学报(自科版),2014,36(2),267-272. 73.杨静,汪超,林亲雄,梅之南,杨光忠,杨新洲*.苦参中lavandulyl侧链取代的黄酮抑制钠-葡萄糖协同转运蛋白2(SGLT2)抑制活性的研究.华中师范大学学报(自科版),2014,48(4),520-524. 74.杨新洲,汪超,杨静,李巍.密花美登木叶化学成分研究.中南民族大学学报(自科版),2014,33(1),48-50. 75.赵平,李明芳,周琦,杨新洲*.IRAP在胰岛素调控中的作用机制研究.医学分子生物学杂志,2014,11(1),43-47. 76.鲁蓝青,梅青,万定荣*,杨新洲,乔舒,赵喻丹.佛甲草及其近缘种垂盆草的HPLC特征指纹图谱研究.中药材,2014,37(4),583-587. 2013 77.LvyiChen*,LanZhou,ShuweiMa,LingZhao,XinzhouYang*.Attenuationofgoutyarthritisbyemodinolinmonosodiumuratecrystal-treatedmice.PlantaMed.,2013,79(8),634-638.(中科院3区,IF2.34) 78.ShashaMo,HuiXiong,GuangwenShu,XinzhouYang,JianxiaWang,CongyiZheng,WeiXiong,ZhinanMei*.PhaseoloidesideE,anovelnaturaltriterpenoidsaponinidentifiedfromEntadaphaseoloides,inducesapoptosisinEc-109esophagealcancercellsthroughreactiveoxygenspeciesgeneration.J.Pharmacol.Sci.,2013,122(3):163-175.(中科院3区,IF2.41) 79.PingSong,JingquanYuan,XinzhouYang*.CytotoxicconstituentsfromPsoraleacorylifolia.J.AsianNat.Prod.Res.,2013,15(6):624-630.(中科院4区,IF1.07) 80.ChaoWang,YeYang,ZhinanMei,XinzhouYang*.CytotoxiccompoundsfromLaminariajaponicaAresch.ChemNatComp.,2013,49(4),699-701.(中科院4区,IF0.46) 81.GuangwenShu,XueMi,JianCai,XinlinZhang,WuYin,XinzhouYang,YouLi,LvyiChen,XukunDeng.Brucine,analkaloidfromseedsofStrychnosnux-vomicaLinn.,represseshepatocellularcarcinomacellmigrationandmetastasis:Theroleofhypoxiainduciblefactor1pathway.ToxicologyLetters,2013,222(2),91-101.(中科院2区,IF3.17) 82.HuiXiong,ZhinanMei,GuangzhongYang,ShashaMo,XinzhouYang,PengZhang,JizhouWu.TriterpenesaponinsfromEntadaphaseoloides.Helv.Chim.Acta,2013,Aug12,96(8),1579-1589.(中科院4区,EI,IF1.07) 83.杨也,许晓娟,肖锋,汪超,万近福,杨新洲*.橙黄瑞香的化学成分研究.云南大学学报(自科版),2013,35(S1),281-285. 84.李游,邓旭坤*,蔡俭,米雪,杨新洲,陈旅翼.猫尾木化学成分的研究.中国当代医药,2013,20(4),4-6. 85.杨静,汪超,杨新洲*.昆布的化学成分研究.湖北民族学院学报(医学版),2013,10,34-35,转39. 86.汪超,杨静,杨新洲*.野花椒化学成分及其体外抗前列腺癌活性研究.湖北民族学院学报(医学版),2013,10,42-45. 2012 87.XinzhouYang,ChunpingTang,PingZhao,GuangwenShu*,ZhinanMei*.AntimicrobialConstituentsfromBletillaochraceaSchltr.PlantaMed.,2012,78,606-610.(中科院3区,IF2.34) 88.JinfuWan,JinquanYuan,ZhinanMei,XinzhouYang*.PhenolicglycosidesfromBoschniakiahimalaica.Chin.Chem.Lett.,2012,23:579-582.(中科院4区,IF1.93) 89.XinzhouYang,JinquanYuan,ZhinanMei,JinfuWan*.CytotoxicPhenolicglycosidesfromBoschniakiahimalaica.Chem.Nat.Comp.,2012,48(4),555-558.(中科院4区,IF0.46) 90.XinzhouYang,XinqiaoLiu,ZhinanMei*.AntibacterialpiperidinealkaloidsfromCassiasiameaLam.AsianJ.Chem.,2012,24(11),5222-5224. 91.WeiRen,LinYuan,JunLi,XianjuHuang*,SuChen,DajiangZhou,XiangmingLiu,XinzhouYang.EthanolicextractofAconitiBrachypodiradixattenuatesnociceptive.AfricanJournalofTraditionalComplementaryandAlternativeMedicines,2012,9(4),574-583. 92.陈玲芳,杨新洲,熊慧,王剑侠,梅之南*.鹰嘴豆化学成分研究.亚太传统医药,2012,8(7),41–43. 2011 93.XinzhouYang,YunjiangFeng,SandraDuffy,VickyMAvery,DavidCamp,RonaldJQuinn*.AnewquinolineepoxidefromtheAustralianplantDrummonditacalida.PlantaMed.,2011,77,1644-1647.(中科院3区,IF2.34) 94.XinzhouYang,IgorBaburin,InkenPlitzko,SteffenHering,MatthiasHamburger*.HPLC-basedactivityprofilingforGABAAreceptormodulatorsfromthetraditionalChineseherbaldrugKushen(Sophoraflavescensroot).Mol.Diversity,2011,15,361-372.(中科院4区,IF1.76) 95.YingluYu,ChangqiangKe,XinzhouYang,YangYe*,MeichunYao*.IsoflavonoidglycosidesfromtheflowersofPuerarialobata,J.AsianNat.Prod.Res.,2011,13(4),284-289.(中科院4区,IF1.07) 96.万近福,袁经权,杨新洲*.制备型高效液相色谱快速分离罗布麻花的黄酮类成分.云南大学学报(自科版),2011,4,463-468. 2010 97.XinzhouYang,RohanA.Davis,MalcolmS.Buchanan,SandraDuffy,VickyM.Avery,DavidCamp,RonaldJ.Quinn*.AntimalariabromotyrosinederivativesfromtheAustralianmarinespongeHyattellasp.J.Nat.Prod.,2010,73,985-987.(中科院2区,IF3.28) 98.PingSong,XinzhouYang,JunYu.NewchemicalcompoundfromCaraganajubata(pall.)Poir.Chem.Res.Chin.Univ.,2010,26,563-566.(中科研4区,IF1.02) 99.YingluYu,XianLi,ChangqiangKe,XinzhouYang,YangYe.IridoidglucosidesfromAllamandaneriifolia.Chin.Chem.Lett.,2010,21(6),709-711.(中科院4区,IF1.93) 100.QingqingFu,JingyouLiu,ChanggongZhang,YinboZhou,GengZhang,DanMa,XinzhouYang.Separationandidentificationofflavonoidsfromfistularonionstalk(AlliumfisturosumL.var.CaespitosumMakio).J.HuazhongUniv.Sci.Technol.(MedSci),2010,30(2),255-257.(中科院4区,IF0.96) 101.袁经权,周小雷,王硕,缪剑华,柯昌强,杨新洲.八角茴香化学成分的研究.中成药,2010,32,(12),2123-2126. 2009 102.XinzhouYang,PeterKünze,InkenPlizolo,OlivierPotterat,MatthiasHamburger*.BicyclononanealdehydesandantiproliferativeconstituentsfromAmomumtsao-ko.PlantaMed.,2009,75,543-546.(中科院3区,IF2.34) 103.XinzhouYang,JianyuZhu,ChunpingTang,ChangqiangKe,GeLin,Tin-YanCheng,JohnA.Rudd,YangYe*.AlkaloidsfromrootsofStemonasessilifoliaandtheirantitussiveactivities.PlantaMed.,2009,75,174-177.(中科院3区,IF2.34) 104.PingSong,XinzhouYang,JunYu.AntifungalactivityofpterocarpansfromCaraganajubata(pall.)Poir.ChinJ.ModernAppl.Pharm.,2009,26,691-694. 2008 105.Li-GenLin1,Xin-ZhouYang1,Chun-PingTang,Chang-QiangKe,Ji-BaoZhang,YangYe*.AntibacterialstilbenoidsfromStemonatuberosa.Phytochemistry,2008,69,457-463.(1co-firstauthor,中科院3区,IF3.23) 106.Jing-QuanYuan,Xin-ZhouYang,Jian-HuaMiao,Chun-PingTang,Chang-QiangKe,Ji-BaoZhang,Xiao-JunMa*,YangYe*.NewantifungaltriterpeneglucosidesfromtherootsofRosalaevigataMichx.Molecules,2008,13,2229-2237.(中科院3区,IF2.86) 107.XinzhouYang,ChunpingTang,ChangqiangKe,YangYe*.Non-alkaloidconstituentsfromStemonasessilifolia.NaturalProductsResearchandDevelopment,2008,20(1),56-59. 108.XinzhouYang,ChunpingTang,ChangqiangKe,YangYe*.StudiesonchemicalconstituentsofStemonajaponica(Bl.)Miq.NaturalProductsResearchandDevelopment,2008,20(3),399-402. 109.袁经权,邹忠杰,杨新洲,缪建华,董月盛,许旭东,杨峻山*.苦石莲化学成分研究.药物分析杂志,2008,28,1489-1493. 110.万近福,杨新洲*.紫地榆化学成分研究.中草药,2008,29(S),18-20. 2007 111.XinzhouYang,TobiasA.M.Gulder,MatthiasReichert,ChunpingTang,ChangqiangKe,YangYe*,GerhardBringmann*.ParvisteminsA-D,anewtypeofdimericphenylethylbenzoquinonesfromStemonaparvifloraWright.Tetrahedron,2007,63,4688-4694.(中科院3区,IF2.65) 112.Xin-ZhouYang,Li-GenLin,Chun-PingTang,Yong-QiangLiu,YangYe*.Non-alkaloidconstituentsfromStemonajaponica.Helv.Chim.Acta,2007,90,318-325.(中科院4区,EI,IF1.07) 113.Xin-zhouYang,Chun-pingTang,Chang-qiangKeandYangYe*.StilbenoidsfromStemonasessilifolia.J.AsianNat.Prod.Res.,2007,9(3),261-266.(中科院4区,IF1.07) 114.Xin-zhouYang,Yi-pingYang,Chun-pingTang,Chang-qiangKeandYangYe*.RapidIdentificationofbibenzylsofStemonasessilifoliabyhyphenatedLC-UV-NMRandLC-MSmethods.Chem.J.Chin.Univ.,2007,23,48-51.(中科院4区,IF0.7) 115.LigenLin,Pham-HuuDien,ChunPingTang,ChangQiangKe,XinZhouYang,YeYang.AlkaloidsfromtherootsofStemonacochinchinensis.Helv.Chim.Acta,2007,90(11),2167-2175.(中科院4区,IF1.07) 116.FanGe,ChangqiangKe,WeiTang,XinzhouYang,ChunpingTang,JianpingZuo,YangYe*.PreparativeisolationofsomechlorogenicacidsandtheirderivativesfromStemonajaponicabyhigh-performanceliquidchromatographyandevaluationoftheiranti-AIV(H5N1)activityinvitro.Phytochem.Anal.,2007,18,213-218.(中科院3区,IF2.29) 2006 117.Xin-zhouYang,Chun-pingTangandYangYe*.StilbenoidsfromStemonajaponica.J.AsianNat.Prod.Res.,2006,8(1-2):47-53.(中科院4区,IF1.07) 2003 118.赵钟祥,杨新洲,唐琛霞,阮金兰.HPLC法测定宫廷补酒中丹参酮ⅡA的含量.中药材,2003,26,440-441. 会议论文 119.XinzhouYang*,XinqiaoLiu,ZhinanMei.AntibacterialpiperidinealkaloidsfromCassiasiameaLam.第四届中药与天然药物现代化新剂型新技术国际学术会议暨世界中医药学会联合会中药新型给药系统专业委员会学术年会,武汉,中国,2011,10月29日-10月30日. 120.JinfuWan,JingquanYuan,ZhinanMei,XinzhouYang*.PhenolicglycosidesfromBoschniakiahimalaica.第四届中药与天然药物现代化新剂型新技术国际学术会议暨世界中医药学会联合会中药新型给药系统专业委员会学术年会,武汉,中国,2011,10月29日-10月30日. 121.XinzhouYang*,ZhinanMei.ProfilingoftwoChinesemedicinalplants,SophoraflavescensandLigusticumchuangxiong,byoff-lineLC-NMRandLC-MS.The2011ChineseMedicinalChemistrySymposium–TheEngineofDrugInnovation,Guangzhou,P.R.China,2011.11.17-2017.11.20. 122.ChaoWang,JingYang,DingrongWan,XinzhouYang*.AntifungalsesquiterpenedimersfromChloranthusmultistachys,InternationalSymposiumofFrontierSciencesonNewDrugDiscoveryandSymposiumofMedicinalChemistryandAntibioticsofPharmaceuticalAssociationofHubeiProvince,Wuhan,P.R.China,2013.12.24-12.25. 123.XinzhouYang.DiscoveryofnewantidiabeticbioactivecompoundsfromtraditionalChineseethnicmedicines.The1stAnnualSymposiumoftheJointLaboratoryofSino-ThaiTraditionalMedicine,Nanning,P.R.China,2014.07.17-2017.07.19. 124.JingYang,ChaoWang,QiZhou,PingZhao,ChanXu,JingnanLv,XinzhouYang*.ChemicalconstituentswithGLUT4translocationactivityfromEucalyptuscitriodora.The28thInternationalSymposiumontheChemistryofNaturalProductsandthe8thInternationalConferenceonBiodiversity,Shanghai,P.R.China,2014.10.29-10.24. 125.JingYang,ChaoWang,QiZhou,PingZhao,ChanXu,JingnanLv,MiHuang,XinzhouYang*.AntidiabeticeffectsoftheEtOAcextractofSophoraflavescensinKK-AydiabeticmiceandHPLCprofilingoftheinvitroAntidiabeticconstituentsfromtheactiveextract.The28thInternationalSymposiumontheChemistryofNaturalProductsandthe8thInternationalConferenceonBiodiversity,Shanghai,P.R.China,2014.10.29-10.24.

学术兼职

中国民族医药学会科研分会常务理事 中国民族医药学会土家医药学分会理事 武汉市中药及天然药物专业委员会委员 瑞士化学会会员 澳大利亚皇家化学会会员

推荐链接
down
wechat
bug