Cheng, Ji-Xin - Purdue University - Department of Chemistry

个人简介

Ji-Xin Cheng was born in Jixi, Anhui Province, P. R. China in 1971. He attended University of Science and Technology of China (USTC) from 1989 to 1994. From 1994 to 1998, he carried out his PhD study on bond-selective chemistry under the supervision of Qingshi Zhu at USTC. As a graduate student, he worked as a research assistant at Universite Paris-sud (France) and the Hong Kong University of Science and Technology (HKUST). After postdoctoral training in Yijing Yan’s group at HKUST and Sunney Xie’s group at Harvard University, Cheng joined Purdue University in 2003 as Assistant Professor. He was promoted to Associate Professor in 2009 and to Full Professor in 2013 in Weldon School of Biomedical Engineering and Department of Chemistry. He was appointed as Scientific Director of Label-free Imaging at Purdue’s Discovery Park in Oct 2014. Professor Cheng is a world-renowned pioneer in the field of spectroscopic imaging. He is authored in over 160 peer-reviewed articles that have been cited more than 10,000 times. He achieved an h-index of 49 (Google Scholar) at the age of 43. His leadership is demonstrated as the organizer of 23 national/international symposia, over 160 invited talks, and as lead editor of the first book on Coherent Raman Scattering Microscopy, published by CRC Press in 2012. His is a co-inventor of CARS microscope which is now available through Olympus and Leica. In 2013 He founded Vibronix Inc which has the mission of saving lives through label-free imaging technology.

近期论文

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Pu Wang, Teng Ma, Mikhail N. Slipchenko, Shanshan Liang, Jie Hui, K. Kirk Shung, Sukesh Roy, Michael Sturek, Qifa Zhou*, Zhongping Chen* & Ji-Xin Cheng*, High-speed Intravascular Photoacoustic Imaging of Lipid-laden Atherosclerotic Plaque Enabled by a 2-kHz Barium Nitrite Raman Laser, Scientific Reports, 2014, 4: 6889. DOI:10.1038/srep06889 (2014) Shuhua Yue, Junjie Li, Seung-Young Lee, Hyeon Jeong Lee, Tian Shao, Bing Song, Liang Cheng, Timothy A. Masterson, Xiaoqi Liu, Timothy L. Ratliff, Ji-Xin Cheng*, Cholesteryl ester accumulation induced by PTEN loss and PI3K/AKT activation underlies human prostate cancer aggressiveness. Cell Metabolism, 2014 March, 18: 393-406. PMID: 24606897, highlight by Nature & Cancer Discovery. Pu Wang, Mikhail N. Slipchenko, James Mitchell, Chen Yang, Eric O. Potma, Xianfan Xu, Ji-Xin Cheng*, “Far-field imaging of non-fluorescent species with sub-diffraction resolution”, Nature Photonics, 2013, 7(6): 449-453, DOI:10.1038/NPHOTON.2013.97 Ling Tong, Yuxiang Liu, Bridget D. Dolash, Yookyung Jung, Mikhail N. Slipchenko, Donald E. Bergstrom, Ji-Xin Cheng*, "Label-free Imaging of Semiconducting and Metallic Carbon Nanotubes in cells and mice Using Transient Absorption Microscopy", Nature Nanotechnology, 2012, 7:56-61, DOI: 10.1038/NNANO.2011.210 Han-Wei Wang Ning Chai, Pu Wang, Song Hu, Wei Dou, David Umulis, Lihong V. Wang, Michael Sturek, Robert Lucht, Ji-Xin Cheng*, “Label-free bond-selective imaging by listening to vibrationally excited molecules”, Phys Rev Lett, 2011, 106: 238106. PMID: 21770549 Y. Jung, M. N. Slipchenko, C. H. Liu, A. E. Ribbe, Z. Zhong, C. Yang and J.-X. Cheng*, “Fast detection of the metallic state of individual single-walled carbon nanotubes using a transient-absorption optical microscope”, Physical Review Letters, 2010, 105: 217401. Tong, L.; Cobley, C. M.; Chen, J.; Xia, Y. and Cheng, J.-X., Bright three-photon luminescence from Au-Ag alloyed nanostructures for bio-imaging with negligible phototoxicity, Angewandte Chemie International Edition 2010, 49: 3485-88. W. He, H. Wang, L. C. Hartmann, J. X. Cheng, P. S. Low, In vivo quantification of rare circulating tumor cells by multiphoton intravital flow cytometry, Proc. Natl. Acad. Sci. USA, 2007, 104: 11760-65. H. Wang, T. B. Huff, D. A. Zweifel, W. He, P. S. Low, A. Wei, J. X. Cheng, In vitro and in vivo two-photon luminescence imaging of single gold nanorods, Proc. Natl. Acad. Sci. USA, 2005, 102: 15752-15756 Wei Wu, Seung-Young Lee, He Wang, Pu Wang, Delong Zhang, Zheng Ouyang, Kinam Park, Xiao-Ming Xu*, Ji-Xin Cheng*, Functional Restoration of Traumatically Injured Spinal Cord by Glycol Chitosan Nanoparticles in a Clinically Relevant Time Window. Biomaterials, 2014 Feb; 35(7):2355-64. doi: 10.1016/j.biomaterials.2013.11.074. Seung-Young Lee, Sungwon Kim, Jacqueline Tyler, Kinam Park*, Ji-Xin Cheng*, Blood-stable, tumor-adaptable micelles for cancer chemotherapy, Biomaterials, 2013 Jan. 34(2): 552-61. PMID: 23079665. Y. Shi, S. Kim, T. B. Huff, R. Borgens, K. Park, R. Shi, J.-X. Cheng. Bock copolymer micelles effectively repair traumatically injured spinal cord white matter. Nature Nanotechnology, 2010, 5: 80-87 H. Chen, S. Kim, L. Li, S. Wang, K. Park, J. X. Cheng. Release of Hydrophobic Molecules from Polymer Micelles into Cell Membranes Revealed by Forster Resonance Energy Transfer Imaging. Proc. Natl. Acad. Sci. USA, 2008, 105: 6596-6601. L. Tong, Y. Zhao, T. B. Huff, M. N. Hansen, A. Wei, J. X. Cheng. Gold nanorods mediate tumor cell death by compromising membrane integrity, Advanced Materials, 2007, 19: 3136-41.