个人简介
EDUCATION
1994-1997 Department of Chemistry, Zhejiang(Hangzhou) University, Hangzhou, CHINA. Received Ph.D. degree in June, 1997 (with Prof. Yongmin Zhang).
1986-1989 Department of Chemistry, Henan Normal University, Xinxiang, CHINA. Received M. Sc. Degree in June, 1989
1982-1986 Department of Chemistry, Henan Normal University, Xinxiang, CHINA. Received B. Sc. Degree in June, 1986
ACADEMIC CAREER
2011-Now Professor, State Key Laboratory and Institute of Elemento-organic Chemistry, Nankai University, Tianjin, CHINA.
2008-2011 Professor, Institute of Elemento-organic Chemistry, Nankai University, Tianjin, CHINA.
2002-2008 Associate Professor, Institute of Elemento-organic Chemistry, Nankai University, Tianjin, CHINA.
1999-2002 Postdoctoral associate, Graduate School of Pharmaceutical Sciences, Osaka University, Osaka, Japan.(with Professo Hidenobu Ohmori and Hatsuo Maeda)
1997-1999 Postdoctoral associate, Institute of Elemento-organic Chemistry, Nankai University, Tianjin, CHINA.(with Professor Ruyu Chen).
1989-1994 Assistant P rofessor and Lecturer, Department of Chemistry, Henan Normal University, Xinxiang, CHINA.
近期论文
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Sequential [1+4]- and [2+3]-Annulation of Prop-2-ynylsulfonium Salts: Access to Hexahydropyrrolo[3,2-b]indoles Jia, Penghao; Zhang, Qinglong; Ou, Qima and Huang You* Org. Lett., 2017, 19, 4664-4667.
Divergent Synthesis of Hydropyridine Derivatives via Nitrogen Containing Lewis Base Mediated Regioselective [4+2] Cyclizations Jin, Hongxing; Li, Erqing and Huang You* Org. Chem. Front., 2017, 4, Doi: 10.1039/C7QO00596B.
Phosphine-Catalyzed Intramolecular Rauhut-Currier Reaction: Enantioselective Synthesis of Hydro-2H-Indole Derivatives Jin, Hongxing; Zhang, Qinglong; Li, Erqing; Jia, Penghao; Li, Ning and Huang You* Org. Biomol. Chem. 2017, 15, 7097-7101.
Phosphine-Mediated Sequential Annulation Reaction: Access to Functionalized Benzofurans and 4,5-Dihydrobenzofurans Liang, Ling; Dong, Xuelin and Huang You* Chem. Eur. J., 2017, 23, 7882-7886.(Hot Paper)
A phosphine mediated sequential annulation process of 2-tosylaminochalcones with MBH carbonates to construct functionalized aza-benzobicyclo [4.3.0] derivates Zhang, Qinglong; Zhu, Yannan; Jin, Hongxing and Huang You* Chem. Commun., 2017, 53, 3974-3977.
[3 + 2]-Annulation of Prop-2-ynylsulfonium Salts: Access to Hydroindol-5-ones Containing a Methylthio Group Jia, Penghao; Zhang, Qinglong; Jin, Hongxing and Huang You* Org. Lett. 2017, 19, 412-415.
Bifunctional Phosphine Catalyzed Sequential Annulations of Allenoates and Ketimines: Construction of Functionalized Poly-heterocycle Rings Li, Erqing; Jin,Hongxing; Jia, Penghao; Dong, Xuelin and Huang You* Angew. Chem. Int. Ed. 2016, 55 (38), 11591-11594 DOI:10.1002/anie.201605189).
Sequential Annulations Domino Reaction of Sulfur Ylides and ???-Unsaturated Cyclic Ketimines: Synthesis of Cyclic 2-Alkenyl Aziridines Jia, Penghao and Huang You* Org. Lett. 2016, 18(10), 2475-2478.
Phosphine-Catalyzed [3 + 3]-Domino Cycloaddition of Ynones and Azomethine Imines To Construct Functionalized Hydropyridazine Derivatives Liang, Ling and Huang You* Org. Lett. 2016, 18(11), 2604-2607.
One-Pot Synthesis of Polysubstituted Benzenes through a N,N-dimethyl-4-aminopyridine (DMAP)-Catalyzed [4+2] Benzannulation of 1,3-Bis(sulfonyl)butadienes and g-Substituted Allenoates Chang, Meijia; Wu, Chengzhou; Zheng, Jie and Huang You* Chem. Asian J. 2016, 11(5), 1512-1517(Hot Paper)
DABCO-Mediated [4 + 4]-Domino Annulation: Access to Functionalized Eight-Membered Cyclic Ethers Liang, Ling; Li, Erqing; Dong, Xuelin and Huang You* Org. Lett. 2015, 17(19), 4914?4917.
Highly Enantioselective Intermolecular Cross Rauhut–Currier Reaction Catalyzed by a Multifunctional Lewis Base Catalyst Dong, Xuelin; Liang, Ling; Li, Erqing and Huang You* Angew. Chem. Int. Ed. 2015, 54, 1621-1624. (Hot Paper)
Divergent Phosphine-Catalyzed [2+4] or [3+2] Cycloaddition Reactions ofγ-Substituted Allenoates with Oxadienes Li, Erqing; Chang, Meijia; Liang, Ling and Huang You* Eur. J. Org. Chem. 2015, 710–714. (Hot Paper)
Morita–Baylis–Hillman adduct derivatives (MBHADs): versatile reactivity in Lewis base-promoted annulation Xie, Peizhong and Huang You* Org. Biomol. Chem. 2015, 13(32), 8578–8595
A Sulfur Ylides-Mediated Domino Benzannulation Strategy to Construct Biaryls, Alkenylated and Alkynylated Benzene Derivatives Gao Fei and Huang You* Adv. Synth. Catal. 2014, 356, 2422-2428.
Phosphine-catalyzed Domino Reaction: A Novel Sequential [2+3] and [3+2] Annulation Reaction of γ-Substituent Allenoates to Construct Bicyclic[3, 3, 0]octene Derivatives. Li, Erqing; Huang, You* Chem. Commun., 2014, 50 (8), 948-950.
Sequential Catalyst Phosphine/Secondary Amine-Promoted [1+4]/ Rearrangement Domino Reaction for the Construction of (2H)-Pyrans and 2-oxabicyclo[2.2.2]oct-5-ene Skeletons Xie, Peizhong; Yang, Jie; Zheng, Jie; Huang, You* Eur. J. Org. Chem., 2014, 1189-1194.
Phosphine-Catalyzed Domino Reaction: A Novel Method Access to Functionalized Bicyclic Skeletons Li, Erqing; Huang, You* Chem. Eur. J., 2014, 20, 3520
Phosphine Initiated Domino Reaction: A Convenient Method for the Preparation of Spiro-cyclopentanones Liang, Ling; Li, Erqing; Xie, Peizhong; Huang You* Chem. Asian J. 2014, 9(5), 1270-1273
Phosphine-Catalyzed Sequential [2 +3] and [3 + 2] Annulation Domino Reaction of γ- Benzyl Substituted Allenoates with α,β-Unsaturated Ketimines To Construct Aza-bicyclo[3, 3, 0]octane Derivatives Li, Erqing; Jia, Penghao; Liang, Ling; Huang, You* ACS Catal. 2014, 4, 600?603.
A simple and highly efficient procedure for construction of quaternary carbons centers by tributylphosphine catalyzed bis-Michael addition Xu, Da-Zen; Zhan, Ming-Zhe; Huang, You* Tetrahedron 2014, 70, 176-180
One step Synthesis of Benzoxazepine Derivatives via a PPh3 Catalyze aza-MBH Domino Reaction between Salicyl N-tosylimines and Allenoates. Zhao, Hongxia; Meng, Xiangtai; Huang, You*Chem. Commun., 2013, 49(89), 10513-10515.
Phosphine-Catalyzed Domino Reaction: An Efficient Method for the Synthesis of Bicyclo[3.2.0]heptenes Skeleton. Zheng, Jie; Huang, You*; Li, Zhengming Org. Lett. 2013, 15(22), 5758-5761.
Phosphine-Catalyzed Domino Benzannulation: An Efficient Method to Construct Biaryl Skeletons. Zheng, Jie; Huang, You*; Li, Zhengming Org. Lett. 2013, 15(19), 5064-5067.
Phosphine-Catalyzed [4+2] Annulation of gamma-Substituent Allenoates: Facile Access to Functionalized Spirocyclic Skeletons. Li, Erqing; Huang, You*; Liang, Ling; Xie Peizhong Org. Lett. 2013, 15(12), 3138-3141.
Tunable Phosphine-Mediated Domino Reaction: Selective Synthesis of 2,3-Dihydrofurans and Biaryls Xie, Peizhong; Li, Erqing; Zheng, Jie; Li, Xin; Huang, You*; Chen, Ruyu Adv. Synth. Catal. 2013, 355(1), 161 – 169. (Hot Paper)
Tuning Catalysts to Tune the Products: Phosphine-Catalyzed Aza-Michael Addition Reaction of Hydrazones with Allenoates. Li, Erqing; Xie, Peizhong; Yang, Lihua, Liang Ling, Huang You*. Chem. Asian J. 2013, 8(3) , 603-610.
Phosphine-Catalyzed Rauhut-Currier Domino Reaction: A Facile Strategy for the Construction of Carbocyclic Spirooxindoles Skeletons Hu, Chongchong; Zhang, Qinglong; Huang, You* Chem. Asian J. 2013, 8(9) , 1981-1984
Domino Cyclization Initiated by Cross-Rauhut-Currier Reactions Xie, Peizhong; Huang, You* Eur. J. Org. Chem. 2013, (20), 6213–6226.
Sulfur Ylides Participating Domino Cyclization Reaction. Li Gongchun; Wang Liye; Huang You* Chin. J. Chem. 2013, 33(9), 1900-1918.