谢周令 - 合肥工业大学 - 食品与生物工程学院

个人简介

谢周令，博士，2017年毕业于中国药科大学药学院，主要从事小分子新药的发现工作。迄今为止，共发表相关高水平论文20余篇，申请专利3项。其中以第一作者或通讯作者在药物化学知名期刊J Med Chem和Eur J Med Chem上发表论文7篇（J Med Chem发表的论文被选为封面文章）。博士期间参与1.1类新药汉黄芩素（已获临床批件）和多种原料药的合成工艺的研究，与多个制药企业保持合作。学习工作简历 2019.12-至今合肥工业大学副教授 2017.6~2019.12 合肥工业大学讲师 2014.9~2017.6 中国药科大学药物化学专业博士 2011.9~2014.6 中国药科大学药物化学专业硕士 2007.9~2011.6 中国药科大学制药工程专业学士

研究领域

1、靶向小分子创新药物的研发（重点聚焦抗血栓药物、抗肿瘤药物研发） 2、原料药的合成工艺研究

近期论文

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Xie Zhouling, Yang Xiaoxiao, Duan Yajun, Han Jihong, Liao Chenzhong*; Small-Molecule Kinase Inhibitors for the Treatment of Nononcologic Diseases, J Med Chem, 2021, 64: 1283-1345. Xie Zhouling*, Li Zhen, Shao Yanruisheng, Liao Chenzhong*; Discovery and development of plasma kallikrein inhibitors for multiple diseases, Eur J Med Chem, 2020, 190: 112137. Xie Zhouling*; Tian Yongbing; Lv Xiao; Xiao Xuan; Zhan Meimiao; Cheng Kai; Li Shiyu; Liao Chenzhong*; The selectivity and bioavailability improvement of novel oral anticoagulants: An overview, Eur J Med Chem, 2018, 146: 299-317. Xie Zhouling; Oscar Benimana; Zhao Lulu; Ding Xue; Cao Chen; Feng Sen; Li Han; Pan Chen; Bian Ziyi; Li Yang; Wang Weijun; Kong Yi*; Li Zhiyu*; Design, synthesis and evaluation of novel 2-amino-3-(naphth-2-yl)propanoic acid derivatives as potent inhibitors of platelet aggregation, Eur J Med Chem, 2017, 125: 197-209. Xie Zhouling; Feng Sen; Wang Ying; Cao Chen; Huang Jing; Chen Yahui; Kong Yi*; Li Zhiyu*; Design, synthesis of novel tryptophan derivatives for antiplatelet aggregation activity based on tripeptide pENW (pGlu-Asn-Trp), Eur J Med Chem, 2015, 102: 363-374. Cheng Kai, Li Shiyu, Lv Xiao, Tian Yongbin, Kong Haiyan, Huang Xufeng, Duan Yajun, Han Jihong, Xie Zhouling*, Liao Chenzhong*, Design, synthesis and biological evaluation of novel human monoamine oxidase B inhibitors based on a fragment in an X-ray crystal structure, Bioorg Med Chem Lett, 2019.4. Li Shiyu, Lv Xiao, Cheng Kai, Tian Yongbing, Huang Xufeng, Kong Haiyan, Duan Yajun, Han Jihong, Liao Chenzhong*, Xie Zhouling*, Discovery of novel 2,3-dihydro-1H-inden-1-amine derivatives as selective monoamine oxidase B inhibitors, Bioorg Med Chem Lett, 2019.4. Lv Xiao, Tian Yongbing, Li Shiyu, Cheng Kai, Huang Xufeng, Kong Haiyan, Liao Chenzhong, Xie Zhouling*, Discovery and Development of Cyclin-Dependent Kinase 8 Inhibitors, Curr Med Chem, 2020.7.