个人简介
2002-2006年西北农林科技大学本科
2006-2009年西北农林科技大学硕士
2010-2013年西北农林科技大学博士
2013年9月-至今合肥工业大学,生物医学工程系讲师获奖情况
2011年度教育部“博士研究生学术新人奖”;
2012年杨凌示范区科学技术一等奖(厅级)(排名第二);
2012陕西省科学技术奖二等奖(省级)(排名第三)。
研究领域
1)非编码RNA对生物钟节律的调节机制研究
2)中药的系统药理学研究
近期论文
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近年来先后在《NucleicAcidResearch》、《RNA》、《CurrentMedicinalChemistry》、《SoftMatter》和《PloSone》等刊物上发表SCI论文30余篇。
1.XuX*,WangX*,LiY,WangY,YangL.Alarge-scaleassociationstudyfornanoparticleC60uncoversmechanismsofnanotoxicitydisruptingthenativeconformationsofDNA/RNA.NucleicAcidsRes.2012,40:7622-7632.(*equalcontributiontofirstauthor)
2.WangX,XuX,MaZ,HuoY,XiaoZ,LiY,WangY.Dynamicmechanismsforpre-miRNAbindingandexportbyExportin-5.RNA.2011.17:1511-1528.
3.WangX,LiY,XuX,WangY.Towardasystem-levelunderstandingofmicroRNApathwayviamathematicalmodeling.Biosystems,2010;100:31-38.
4.TaoW,XuX,WangX,YuH,LiX,LiB,WangY.YangL.Networktarget-baseduncoveringthemechanismofactionofChineseherbalRadixCurcumaeformulawithapplicationtocardiovasculardisease.JournalofEthnopharmacology.
5.ZhouW,LiY,WangX,WuL,WangY.MiR-206-mediateddynamicmechanismofthemammaliancircadianclock.BMCSystBiol.2011,5:141-157.
6.WangX,XuX,LiY,LiX,TaoW,LiB,WangY,YangL.SystemspharmacologyuncoversJanusfunctionsofbotanicaldrugs:activationofhostdefensesystemandinhibitionofinfluenzavirusreplication.IntegrBiol(Camb).2013,28;5(2):351-71.
7.WangX,XuX,TaoW,LiY,WangY,YangL.Asystemsbiologyapproachtouncoveringpharmacologicalsynergyinherbalmedicineswithapplicationstocardiovasculardisease.EvidBasedComplementAlternatMed.2012:519031doi:10.1155/2012/519031.
8.WangX,XuX,MaM,ZhouW,WangY,YangL.pH-dependentchannelgatinginconnexin26hemichannelsinvolvesconformationalchangesinN-terminus.BiochimBiophysActaBiomembr.2012;1818:1148-1157.
9.WangX,XuX,ZhuS,XiaoZ,MaZ,LiY,WangY.MoleculardynamicssimulationofconformationalheterogeneityinTransportin1.Proteins.2012;80:382?397.
10.XuX*,WangX*,XiaoZ,LiY,WangY.TwoTPX2-DependentSwitchesControltheActivityofAuroraA.PLoSONE,2011;6(2):e16757.(*equalcontributiontofirstauthor)
11.XuX*,WangX*,XiaoZ,LiY,WangY.Probingthestructuralandfunctionallinkbetweenmutation-andpH-dependenthydrationdynamicsandamyloidosisoftransthyretin.Softmatter.2012;8:324-336.(*equalcontributiontofirstauthor)
12.XuX,LiR,MaM,WangX,WangY,ZouH.MultidrugresistanceproteinP-glycoproteindoesnotrecognizenanoparticleC60:experimentandmodeling.SoftMatter,2012,8:2915-2923.
13.XiaoZ,WangX,XuX,ZhangH,LiY,WangY.Base-andStructure-DependentDNADinucleotide-CarbonNanotubeInteractions:MolecularDynamicsSimulationsandThermodynamicAnalysis.J.Phys.Chem.C,2011,115(44):21546-21558.(coverpaper)
14.WangX,YangW,XuX,ZhangH,LiY,WangY.StudiesofbenzothiadiazinederivativesashepatitisCvirusNS5Bpolymeraseinhibitorsusing3D-QSAR,moleculardockingandmoleculardynamics.CurrMedChem.2010;17:2788-2803.