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个人简介

2016年9月---至今:合肥工业大学,食品科学与工程学院任教; 2012年7月---2016年6月:合肥工业大学,农产品生物化工教育部工程研究中心任教; 2006年9月---2012年6月:合肥工业大学,生物与食品工程学院,农产品加工及贮藏工程专业,工学博士; 2002年9月---2006年6月:合肥工业大学,生物与食品工程学院,生物技术专业,理学学士。开设课程 硕士生课程:《农产品加工系统工程》、《食品资源综合利用》。 近年的科研项目(五年内) 1.安徽省科技攻关计划项目,年产1000吨蔬菜全粉加工关键技术研究及应用(编号1704a07020094),2017/01-2019/12,在研,主持。 2.国家自然科学基金青年基金项目(编号21501039),复合磁性纳米氧化物的制备与肝癌靶向诊疗一体化的研究,2016/01-2018/12,在研,参加。 3.国家自然科学基金青年基金项目(编号21302037),P-糖蛋白抑制载体调控丹参素前药设计及脑靶向给药的研究,2014/01-2016/12,结题,参加。

研究领域

天然产物开发与利用

近期论文

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1.HanGao,Wen-chengZhang,Bing-songWang,Ai-lingHui,BiaoDu,Ting-tingWang,LingMeng,Hui-xiBian,andZe-YuWu*.Purification,characterizationandanti-fatigueactivityofpolysaccharidefractionsfromokra(Abelmoschusesculentus(L.)Moench).Food&Function,2018,DOI:10.1039/C7FO01821E. 2.Ting-TingWang,Yong-HongSong,Wen-ChengZhang,Ze-YuWu*,FeiLi,YangSu,YiYang,Fang-YuanLi,Peng-PengChen,JingWang,QiangWu,Xiao-LianSun,YangLu*,andDai-ShunLing*.StableGoldNanorodsConjugatedLiposomalPodophyllotoxinNanocompositesforSynergisticChemo-PhotothermalCancerTherapy.JournalofBiomedicalNanotechnology.2017,13(11):1435-1445. 3.Wen-ChengZhang,BingLi,Bing-SongWang,XiuliDong,andZe-YuWu*.Enzyme-assistedextractionofcordycepinandadenosinefromculturedCordycepsmilitarisandpurificationbymacroporousresincolumnchromatography.SeparationScienceandTechnology,2017,52(8):1350-1358. 4.Ai-LingHui*,YuanWang,Kai-LiZhu,Jing-ChaoChen,Qing-PingFan,AnZhou,Wen-ChengZhang,andZe-YuWu.Synthesisandevaluationofnovelascorbylcinnamatesaspotentialanti-oxidantandantimicrobialagents.ResearchonChemicalIntermediates,2017,43(10):5901-5916. 5.Wen-ChengZhang,QingZhang,Xing-YuanZhang*,Ze-YuWu*,BingLi,XiuliDong,andBingsongWang.PreparationandevaluationofmolecularlyimprintedcompositemembranesforinducingcrystallizationofoleanolicacidinsupercriticalCO2.AnalyticalMethods,2016,8(28):5651-5657. 6.Hui-XiBian,Ze-YuWu,BinBao,JingCai,XinWang,YingJiang,JianLiuandWeiQu*.1HNMR-basedmetabolicstudyrevealstheimprovementsofbittermelon(Momordicacharantia)onenergymetabolismindiet-inducedobesemouse.PharmaceuticalBiology,2016,54(12):3103-3112. 7.JuanLiang,JianPan*,Ze-YuWu,MeiGe,andJin-FengXu.EffectsofhighpressureinassociationwithpHandsaltontheallergenicity,proteolyticandfibrinolyticactivitiesofpineapplejuice.QualityAssuranceandSafetyofCrops&Foods,2016,8(3):319-326. 8.AnZhou#,ZeyuWu#,Ai-LingHui,BinWang,Xian-ChunDuan,Hai-XiangWang,andJianPan*.3D-QSARandMolecularDockingStudiesofFlavonoidDerivativesasPotentAcetylcholinesteraseInhibitors.LettersinDrugDesign&Discovery,2015,12(10):837-843. 9.AnZhou,HongfeiWu,JianPan*,XuncuiWang,JiamingLi,Ze-YuWu,andAilingHui*.SynthesisandevaluationofpaeonolderivativesaspotentialmultifunctionalagentsforthetreatmentofAlzheimer’sDisease.Molecules,2015,20(1):1304-1318. 10.AnZhou,Jian-PingHu,Li-RongWang,Guo-ChenZhong,JianPan*,Ze-YuWu,andAi-LingHui*.Combined3D-QSAR,moleculardockingandmoleculardynamicsstudyoftacrinederivativesaspotentialacetylcholinesterase(AChE)inhibitorsofAlzheimer'sdisease.JournalofMolecularModeling,2015,21(10):1-12. 11.Ai-LingHui*,Ze-YuWu,YuanYuan,AnZhou,andJianPan.ProgressinSynthesisandAntagonisticActivitiestowardsPAFRandGlyRofGinkgolideDerivativesandAnalogs.ChineseJournalofOrganicChemistry,2013,33(6):1263-1272. 12.YuanYuan*,JianPan,Ze-YuWu,Ai-LingHui,andAnZhou.ValidatedLC-MS-MSMethodfortheDeterminationofProdrugofGinkgolideBinRatPlasmaandBrain:ApplicationtoPharmacokineticStudy.JournalofChromatographicScience,2013,51(3):266-272. 13.Shuang-JieZhu,JianPan*,BinZhao,JuanLiang,Ze-YuWu,Jun-JieYang.ComparisonsonenhancingtheimmunityoffreshanddryCordycepsmilitarisinvivoandinvitro.JournalofEthnopharmacology,2013,149(3):713–719. 14.Ze-YuWu*,JianPan,YuanYuan,Ai-LingHui,YiYang,AnZhou,MinTao,andXiao-JianZhou.Brain-targetingresearchof10-O-nicotinateginkgolideB:anewprodrugofginkgolideB.MedicinalChemistryResearch,2012,21(12):4028-4036. 15.Ze-YuWu*,JianPan,YuanYuan,Ai-LingHui,YiYang,andAnZhou.Comparisonofpredictionmodelsforbloodbrainbarrierpermeabilityandanalysisofthemoleculardescriptors.DiePharmazie,2012,67(7):628-634. 16.JianPan,Ze-YuWu*,YuanYuan,AilingHui,andYiYang.SimultaneousDeterminationofProdrugofGinkgolideBandGinkgolideBinRatPlasmabyLC-MS/MS.LatinAmericanJournalofPharmacy,2011,30(6):1167-1172. 17.WenchengZhang*,Hai-TaoZhang,QingZhang,Yan-FangCui,Ze-YuWu,Ren-JuanZheng,andLingLiu.MolecularlyimprintedpolymerspreparedbyprecipitationpolymerizationandusedforinducingcrystallizationofoleanolicacidinsupercriticalCO2.SeparationandPurificationTechnology,2011,81(3):411-417. 18.JianPan,Xiu-HengXue*,Ju-HuaWang,Hui-MingXie,andZe-YuWu.RecognitionpropertyandpreparationofStaphylococcusaureusproteinA-imprintedpolyacrylamidepolymersbyinverse-phasesuspensionandbulkpolymerization.Polymer,2009,50(11):2365-2372.

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