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自2012年发表的论文(*:通讯作者)
1.LiangY,HanH,LiuL,DuanY,YangX,MaC,ZhuY,HanJ,LiX*,ChenY*.CD36playsacriticalroleinproliferation,migrationandtamoxifen-inhibitedgrowthofER-positivebreastcancercells.Oncogenesis2018;7:98
2.MaJ,ZhaoD,WangX,MaC,FengK,ZhangS,ChenY,ZhuY,GaoX,ZhaoB,WangY,QianK,LiX,DuanY,HanJ*,YangX*.LongShengZhicapsulereducesestablishedatheroscleroticlesionsinapoEdeficientmicebyamelioratinghepaticlipidmetabolismandinhibitinginflammation.JournalofCardiovascularPharmacology2018Dec10.doi:10.1097/FJC.0000000000000642
3.LiuY,WeiZ,ZhangY,MaX,ChenY,YuM,MaC,LiX,CaoY,LiuJ,HanJ,YangX*,DuanY*.ActivationofliverXreceptorplaysacentralroleinantiviralactionsof25-hydroxycholesterol.JournalofLipidResearch2018;59:2287-2296(封面论文)
4.HanH,YangS,LiangY,ZengP,LiuL,YangX,DuanY,HanJ,ChenY*.TeniposideregulatesthephenotypeswitchingofvascularsmoothmusclecellsinamiR-21-dependentmanner.BiochemicalandBiophysicalResearchCommunications2018;506:1040-1046
5.VariyaBC,BakraniaAK,ChenY,HanJ,PatelSS.Suppressionofabdominalfatandanti-hyperlipidemicpotentialofEmblicaofficinalis:UpregulationofPPARsandidentificationofactivemoiety.Biomedicine&Pharmacotherapy2018;108:1274-1281
6.LiuL,ZengP,YangX,DuanY,ZhangW,MaC,ZhangX,YangS,LiX,YangJ,LiangY,HanH,ZhuY,HanJ*,ChenY*.Inhibitionofvascularcalcification—Anewanti-atherogenicmechanismofDNAtopoisomeraseIIinhibitors.Arteriosclerosis,ThrombosisandVascularBiology2018;38:2382-239
7.LiQ,ChenY,ZhaoD,WeiZ,ZhangS,ChenY,WangY,QianK,ZhaoB,ZhuY,GaoX,DongP,LiX,DuanY,HanJ*,YangX*.NaoXinTongCapsuleInhibitsCarrageenan-InducedThrombosisinMice.JournalofCardiovascularPharmacology2018;72:49-59
8.YangS,LiuM,ChenY,MaC,LiuL,ZhaoB,WangY,LiX,ZhuY,GaoX,KongD,DuanY,HanJ*,YangX*.NaoXinTongCapsulesinhibitthedevelopmentofdiabeticnephropathyindb/dbmice.ScientificReports2018;8:9158
9.MaC,ZhangW,LiuY,LiuL,YangX,FengK,ZhangX,YangS,SunL,YuM,YangJ,LiX,MiaoQR,ZhuY,HanJ*,ChenY*,DuanY*.FunctionalinterplaybetweenLXRandAMPKαreducesinhibitsatherosclerosisticlesionsinapoEknockoutmice-deficientmice--Anewanti-atherogenicstrategy.BritishJournalofPharmacology2018;175:1486-1503
10.OwoichoOrgahJ,WangM,YangX,WangZ,WangD,ZhangQ,FanG,HanJ,QinG,GaoX,ZhuY.DanhongInjectionprotectsagainsthypertension-inducedrenalinjuryviadown-regulationofmyoglobinexpressioninspontaneouslyhypertensiverats.KidneyandBloodPressureResearch2018;43:12-24
11.LiuY,WeiZ,MaX,YangX,ChenY,SunL,YuM,MaC,GuJ,MiaoRQ,HajjarDP,HanJ*,DuanY*.25-Hydroxycholesterolinducesitsownproductionbyactivatingcholesterol25-hydroxylaseexpressioninanLXRdependentmechanism.JournalofLipidResearch2018;59:439-451
12.ZhangW,YangX,ChenY,HuW,LiuL,ZhangX,LiuM,SunL,LiuY,YuM,LiX,LiL,ZhuY,MiaoQR*,HanJ*,DuanY*.ActivationofhepaticNogo-Breceptorexpression--Anewanti-liversteatosismechanismofstatins.BBA-MolecularCellBiologyofLipid2018;1863:177-190
13.ChenX,FengY,ShenX,PanG,FanG,GaoX,HanJ,ZhuY.Anti-sepsisprotectionofXuebijinginjectionismediatedbydifferentialregulationofpro-andanti-inflammatoryTh17andTregulatorycellsinamurinemodelofpolymicrobialsepsis.JournalofEthnopharmacology2018;211:358-365
14.LyuM,YanC,LiuH,ChenX,WangY,HanJ,FanG,ZhuY.NetworkpharmacologyexplorationrevealsendothelialinflammationasacommontargetforcoronaryarterydiseaseandstroketreatmentbyDanhonginjection.ScientificReports2017;7:15427
15.YangX,OrgahJ,WangD,FanG,JingyangH,HanJ,QinG,GaoX,ZhuY.Danhonginjectionreducesvascularremodelingandup-regulatestheKallikrein-kininsysteminspontaneouslyhypertensiverats.ScientificReports2017;7:4308
16.SunL,YangX,LiQ,ZengP,LiuY,LiuL,ChenY,YuM,MaC,LiX,LiY,ZhangR,ZhuY,MiaoQ,HanJ*,DuanY*.Activationofadiponectinreceptorregulatesproproteinconvertasesubtilisin/kexintype9expressionandinhibitslesionsinapoEdeficientmice.Arteriosclerosis,ThrombosisandVascularBiology2017;37:1290-1300
17.YuM,LiuY,DuanY,ChenY,HanJ,SunL,YangX.InhibitionofglutathioneproductionbyL-S,R-buthioninesulfoximineactivateshepaticascorbatesynthesis--auniqueanti-oxidativestressmechanisminmice.BiochemicalandBiophysicalResearchCommunications2017;484:56-63
18.YangX,LiY,SunL,LiuY,MaC,ChenY,TanH,LiQ,LiX,WangY,DuanY,ZhaoB*,HanJ*.NaoXinTongenhancesatorvastatin-reducedatherosclerosiswhileantagonizingatorvastatin-inducedhepaticinflammation.JournalofCardiovascularPharmacology2017;69:55-64
19.HeS,ZhaoT,GuoH,MengY,QinG,GoukassianDA,HanJ,GaoX,ZhuY.CoordinatedactivationofVEGF/VEGFR-2andPPARdpathwaysbyamulti-componentChinesemedicineDHIacceleratedrecoveryfromperipheralarterialdiseaseintype2diabeticmice.PLoSOne2016;11:e0167305
20.ZhangK,CaiHX,GaoS,YangGL,DengHT,XuGC,HanJ,ZhangQZ,LiLY.TNFSF15suppressesVEGFproductioninendothelialcellsbystimulatingmiR-29bexpressionviaactivationofJNK-GATA3signals.Oncotarget2016;7:69436-69449
21.HuW,ZhangW,ChenY,RanaU,TengR,DuanY,LiuZ,ZhaoB,FoecklerJ,WeilerH,KallingerRE,ThomasMJ,ZhangK,HanJ*,MiaoQR*.Nogo-BreceptordeficiencyincreasesLXRanucleartranslocationandhepaticlipogenesis.Hepatology2016;64:1559-1576
22.YuM,JiangM,ChenY,ZhangS,ZhangW,YangX,LiX,LiY,DuanS,HanJ*,DuanY*.2016.InhibitionofmacrophageCD36expressionandcellularoxLDLaccumulationbytamoxifen--APPARgdependentmechanism.TheJournalofBiologicalChemistry2016;291:16977-89(封面论文)
23.YangX,ZhangW,ChenY,LiY,SunL,LiuY,LiuM,YuM,LiX,HanJ*,YajunDuan*.2016ActivationofPPARgandCD36expression--thedualpathophysiologicalroleofprogesterone.TheJournalofBiologicalChemistry2016;291:15108-18
24.ZhangL,ChenY,YangX,YangJ,CaoX,LiX,LiLY,MiaoQR,HajjarDP,DuanY*,HanJ*.2016.MEK1/2inhibitorsactivatemacrophageABCG1expressionandreversecholesteroltransport--ananti-atherogenicfunctionofERK1/2inhibition.BBA-MolecularandCellBiologyofLipid2016;1861:1180-1191
25.WangQ,SunL,YangX,MaX,LiQ,ChenY,LiuY,ZhangD,LiX,XiangR,WeiY,HanJ*,DuanY*.2016.ActivationofliverXreceptorinhibitsthedevelopmentofpulmonarycarcinomasinducedby3-methylcholanthreneandbutylatedhydroxytoluene.ScientificReports2016;6:27295
26.YangM,OrgahJ,ZhuJ,FanG,HanJ,WangX,ZhangB,ZhuY.DanhongInjectionattenuatescardiacinjuryinducedbyischemicandreperfusedneuronalcellsthroughregulatingargininevasopressinexpressionandsecretion.BrainResearch2016;1642:516-23
27.ZhangY,ShenL,StupackDG,BaiN,XunJ,RenG,HanJ,LiL,LuoY,XiangR,TanX.JMJD3promotessurvivalofdiffuselargeB-celllymphomasubtypesviadistinctmechanisms.Oncotarget2016;7:29387-9928.LiX,CaoX,ZhangX,KangY,ZhangW,YuM,MaC,HanJ,DuanY,ChenY.MEK1/2inhibitorsinduceinterleukin-5expressioninmousemacrophagesandlymphocytes.BiochemicalandBiophysicalResearchCommunications2016;473:939-46
29.LiuM,ZhangW,LiX,HanJ,ChenY,DuanY.ImpactofageandsexonthedevelopmentofatherosclerosisandexpressionoftherelatedgenesinapoEdeficientmice.BiochemicalandBiophysicalResearchCommunications2016;469;456-462
30.YangX,SunL,LiY,MaC,YangJ,ZhangW,ZhaoB,JiaL,DuanY,HanJ,LiX*,ChenY*.NaoXinTonginhibitstheadvancedatherosclerosisandenhancestheplaquestabilityinapoEdeficientmice.JournalofCardiovascularPharmacology2016;67:203-11
31.YangX,YaoH,ChenY,SunL,MaX,DuanS,LiX,XiangR,HanJ*,DuanY*.InhibitionofglutathioneproductioninducesmacrophageCD36expressionandenhancescellularoxLDLuptake.TheJournalofBiologicalChemistry2015;290:21788-21799
32.LiuM,PanQ,ChenY,YangX,ZhaoB,JiaL,ZhuY,ZhangB,GaoX,LiX,HanJ*,DuanY*.AdministrationofDanhongInjectiontodiabeticdb/dbmiceinhibitsthedevelopmentofdiabeticretinopathyandnephropathy.ScientificReports2015;5,11219
33.LiuM,ChenY,ZhangL,WangQ,MaX,LiX,XiangR,ZhuY,QinS,YuY,JiangX,DuanY,HanJ*.RegulationofhepaticcholesterylestertransferproteinexpressionandreversecholesteroltransportbyinhibitionofDNAtopoisomeraseII.TheJournalofBiologicalChemistry2015;290:14418–14429
34.ZhangW,WangX,HuW,LiuL,LiX,HanJ,ChenY*,DuanY*.Co-treatmentofpitavastatinanddexamethasoneexacerbatesthehighfatdiet-inducedatherosclerosisinapoE-/-mice.JournalofCardiovascularPharmacology2015;66:189-95
35.MaX,LiuY,WangQ,ChenY,LiuM,LiX,XiangR,WeiY,DuanY*,HanJ*.TamoxifeninducesthedevelopmentofherniainmicebyactivatingMMP-2andMMP-13expression.BBA-MolecularBasisofDiseases2015;1852:1038-104836.ChenY,DuanY,YangX,SunL,LiuM,WangQ,MaX,ZhangW,LiX,HuW,MiaoQR,XiangR,HajjarDP,HanJ*.InhibitionofERK1/2andactivationofLXRsynergisticallyreduceatheroscleroticlesionsinapoEdeficientmice.Arteriosclerosis,ThrombosisandVascularBiology2015;35:948-959
37.LiuM,PanQ,ChenY,YangX,ZhaoB,JiaL,ZhuY,HanJ,LiX*,DuanY*.NaoXinTonginhibitsthedevelopmentofdiabeticretinopathyindb/dbmice.Evidence-BasedComplementaryandAlternativeMedicineVolume2015;ArticleID242517,8pages,http://dx.doi.org/10.1155/2015/242517
38.MaX,WangQ,LiuY,ChenY,ZhangL,JiangM,LiX,XiangR,MiaoRQ,DuanY*,HanJ*.InhibitionoftumorgrowthbyU0126isassociatedwithinductionofinterferon-gproduction.InternationalJournalofCancer2015;136:771-783(封面论文)
39.WangQ,MaX,ChenY,ZhangL,JiangM,LiX,XiangR,MiaoR,HajjarDP,DuanY*,HanJ*.Identificationofinterferon-gasanewmoleculartargetofliverXreceptor.BiochemicalJournal2014;459:345-354(专评论文:BiochemicalJournal.2014;459:e1-e3)
40.ChenY,LiuM,ZhaoT,ZhaoB,JiaL,ZhuY,ZhangB,GaoX,LiG,LiX,XiangR,HanJ,DuanY*.DanhongInjectioninhibitsthedevelopmentofatherosclerosisinbothApoe-/-andLdlr-/-mice.JournalofCardiovascularPharmacology2014;63:441-452
41.LiuM,ChenY,YangX,ZhangL,ZhaoT,ZhaoB,JiaL,ZhuY,GaoX,ZhangB,LiX,HanJ,DuanY*.DanhonginjectioninhibitsthedevelopmentofprimaryabdominalaorticaneurysmsinapoEknockoutmice.ChineseScienceBulletin2014;59:1366-1373
42.YuanJ,ZhangD,WangL,LiuM,MaoJ,YinY,YeX,LiuN,HanJ,GaoY,ChengT,KeefeDL,LiuL.Noevidenceforneo-oogenesismaylinktoovariansenescenceinadultmonkey.StemCells2013;31:2538-2550
43.JiangM,ZhangL,MaX,HuW,ChenY,YuM,WangQ,LiX,YinZ,ZhuY,GaoX,HajjarDP,DuanY*,HanJ*.TamoxifeninhibitsmacrophageFABP4expressionthroughthecombinedeffectsofGRandPPARgpathways.BiochemicalJournal2013;454:467-477
44.QiaoL,WuQ,LuX,ZhouY,Fernández-AlvarezA,YeL,ZhangX,HanJ,CasadoM,LiuQ.SREBP-1aactivationbyHBxandtheeffectonhepatitisBvirusenhancerII/corepromoter.BiochemicalBiophysicalResearchCommunication2013;432:643-649ZhangL,JiangM,ShuiY,ChenY,WangQ,HuW,MaX,LiX,LiuX,CaoX,LiuM,DuanY*,HanJ*.DNAtopoisomeraseIIinhibitorsinducemacrophageABCA1expressionandcholesterolefflux---anLXR-dependentmechanism.BBA-MolecularandCellBiologyofLipids2013;1831:1134-1145
46.MengX,ZhangY,JiaZ,HuoX,HeX,TianG,WuM,WangZ,ZhouX,XiongS,GaoX,WuZ,HanJ,ZhaoL,WangP,HongZ,WangQ,YinZ.AnoveltylophorineanalogW-8up-regulatesforkheadboxP3expressionandamelioratesmurinecolitis.JournalofLeukocyteBiology2013;93:83-93
47.ChenY,DuanY*,KangY,YangX,LiG,YinZ,HuW,DongP,LiX,HajjarDP,HanJ*.ActivationofliverXreceptorinducesmacrophageinterleukin-5expression.TheJournalofBiologicalChemistry2012;287:43340-43350
48.DuanY,ChenY,HuW,LiX,ZhouX,YinZ,KongD,HajjarDP,LiuL,LiuQ,HanJ*.PPARgactivationbyligandsanddephosphorylationinducesPCSK9andLDLRexpression.TheJournalofBiologicalChemistry2012;287:23667-23677
49.HuW,ZhouX,JiangN,DuanY,ChenY,LiX,YinZ,HeG,YaoZ,ZhuY,HajjarDP,HanJ*.Statinssynergizedexamethasone-inducedadipocytefattyacidbindingproteinexpressioninmacrophages.Atherosclerosis2012;222:434-443
50.ZhengW,WangZ,SongL,ZhaoQ,ZhangJ,LiD,WangS,HanJ,ZhengXL,YangZ,KongD.EndothelializationandpatencyofRGD-functionalizedvasculargraftsinarabbitcarotidarterymodel.Biomaterials2012;33:2880-2891