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个人简介

eng Wang received his B.Sc. degree in Polymer Science and Engineering from Hefei University of Technology in 2007. He received his Ph.D. from the University of Science and Technology of China under the mentorship of Prof. Jun Wang in 2012 and was a postdoctoral fellow at the University of Waterloo with Prof. Juewen Liu from 2012 to 2016. He is currently a Professor of Biomedical Engineering at Hefei University of Technology. He was awarded by the “Hundred Talents Program” of Auhui, China (2017) and “Distinguished Young Scientists” of Anhui, China (2018). His current research involves bio/nano interfaces, especially using the liposome as a model cell membrane system. He has published 49 papers, with over 2000 citation

研究领域

Our research activities are mainly in the areas of lipid and nucleic acid nanotechnology, bioanalytical chemistry, chemical biology, and bioengineering. Our research aim is to develop liposome and nucleic acid-functionalized nanomaterials for biosensor, disease diagnostics and therapy. Our main research interest is in Nano-Bio Interface, especially focused on lipid and nucleic acid chemistries, including: Model cell membranes techniques in membrane biochemistry and biophysics: from liposome to biomimetic supported lipid bilayer Lipid-nanostructure hybrids and their applications in nanotechnology Design of lipid or nucleic acid based nanomaterials as analytical tools for sensing, imaging and diagnostics Chemistries and biologies for DNA Nanotechnology Process for the production of pure lecithin and phospholipids directly usable for physiological purposes

近期论文

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Z. F. Wang♯, Y. Yan♯, C. Li♯, Y. Yu, S. Cheng, S. Chen, X. J. Zhu, L. P. Sun, W. Tao, J. W. Liu, F. Wang*, Fluidity-guided assembly of Au@Pt on liposomes as a catalase-powered nanomotor for effective cell uptake in cancer cells and plant leaves, ACS Nano, 2022, doi: 10.1021/acsnano.2c00327. Y. Yu♯, Z. F. Wang♯, S. C. Wu, C. M. Zhu, X. S. Meng, C. Li, S. Cheng, W. Tao, F. Wang* A Glutathione-Sensitive Nanoglue Platform with Effective Nucleic Acids Gluing onto Liposomes for Photo-Gene Therapy. ACS Applied Materials & Interfaces, 2022, 14, 25126-25134. L. P. Sun♯, Y. Yan♯, S. Chen, Z. J . Zhou, W. Tao, C. Li*, Y. Feng*, F. Wang*, Co-N-C single-atom nanozymes with oxidase-like activity for highly sensitive detection of biothiols. Analytical and Bioanalytical Chemistry, 2022, 1857-1865. Y. Yan♯ , X. J. Zhu♯ , Y. Yu♯ , C. Li, Z. L. Zhang*, F. Wang*, Nanotechnology strategies for plant genetic engineering. Advanced Materials, 2022, 2106945. S. Chen♯ , Y. Yan♯ , Y. Yu♯ , Z. F. Wang, X. J. Zhu, L. P. Sun, C. Li, F. Wang*, Ferric Ions as a Catalytic Mediator in Metal-EGCG Network for Bactericidal Effect and Pathogenic Biofilm Eradication at Physiological pH. Advanced Materials Interfaces, 2021, 202101605 R. K. Gao, C. B. Zhan, C. Y. Wu, Y. Lu, B. Q. Cao, J. Huang, F. Wang, L. D. Yu*, Simultaneous single-cell phenotype analysis of hepatocellular carcinoma CTCs using SERS-aptamer based microfluidic chip. Lab on a Chip, 2021, 21, 3888-3898 L. P. Sun♯, C. Li♯, Y. Yan, Y. Yu, H. Zhao, Z.J. Zhou, F. Wang*, Y. Feng*, Engineering DNA/Fe-N-C single-atom nanozymes interface for colorimetric biosensing of cancer cells. Analytica Chimica Acta, 2021, 1180, 338856 H. Li♯, M. L. Li♯, Y. C. Yang, F. Wang, F. Wang*, Chao Li*, Aptamer-Linked CRISPRCas12a-Based Immunoassay. Analytical Chemistry, 2021, 93, 3209-3216 P. P. Deng♯, Y. Y. Pei♯, M. L. Liu, W. Z. Song, M. R. Wang, F. Wang*, C. X. Wu, L. Xu*, A rapid “on-off-on” mitochondria-targeted phosphorescent probe for selective and consecutive detection of Cu2+ and cysteine in live cells and zebrafish. RSC Advances, 2021,11, 7610-7620 J. Y. Huang♯, M. Jian♯, S. H. Chen♯, S. Y. Zhang, T. Liu*, C. Li*, F. Wang*, A label-free electrochemical biosensor for highly sensitive detection of gliotoxin based on DNA nanostructure/MXene nanocomplexes. Biosensors and Bioelectronics, 2020, 143, 112310 B. M. Hao, Y. N. Liu, C. Y. Zhang, G. Q. Li, W. N. Wang, W. D. Xu, Z. B. Zha, F. Wang, C. Li, Z. H. Miao, X. X. Yang, Y. Li. Chen, H. S. Qian*, W. Zhou*, Autophagic blockage by bismuth sulfide nanoparticles inhibits migration and invasion of HepG2 cells. Nanotechnology, 2020, 31, 465102 R. K. Gao*, L. Cheng, S. Y. Wang, X. B. Bi, X. L. Wang, R. Wang, X. Y. Chen, Z. B. Zha, F. Wang, X. F. Xu, G. Zhao*, L. D. Yu*, Efficient separation of tumor cells from untreated whole blood using a novel multistage hydrodynamic focusing microfluidics. Talanta, 2020, 207, 120261 Y. C. Ma♯, Y. X. Zhang♯, X. Q. Li♯, Y. Y. Zhao, M. Li, W. Jiang, X. F. Tang, J. X. Dou, L. G. Lu, F. Wang*, Y. C. Wang*, Near-infrared II phototherapy induces deep tissue immunogenic cell death and potentiates cancer immunotherapy. ACS Nano, 2019, 13, 11967-11980 H. Wang, H. Li, Y. Huang, M. H. Xiong, F. Wang*, C. Li*, A label-free electrochemical biosensor for highly sensitive detection of gliotoxin based on DNA nanostructure/MXene nanocomplexes. Biosensors and Bioelectronics, 2019, 142, 111531 X. S. Wang♯, X. Q. Li♯, H. Wang, X. H. Zhang, L. Zhang, F. Wang* and J. W. Liu*, Charge and Coordination Directed Liposome Fusion onto SiO2 and TiO2 Nanoparticles. Langmuir, 2019, 35, 5, 1672-1681 L. Zhang, J. Xu, F. Wang, Y. Ding, T. Wang, G. Jin, M. Martz, Z. Z. Gui, P. K Ouyang* and P. Chen*, Histidine-Rich Cell-Penetrating Peptide for Cancer Drug Delivery and Its Uptake Mechanism. Langmuir, 2019, 35, 3513-3523 L. Zhang*, Y. B. Sheng, A. Z. Yazdi, K. Sarikhani, F. Wang, Y. S. Jiang, J. W. Liu, Tao Zheng, W. Wang, P. K Ouyang* and P. Chen*, Surface-assisted assembly of a histidine-rich lipidated peptide for simultaneous exfoliation of graphite and functionalization of graphene nanosheets. Nanoscale, 2019, 11, 2999-3012 Y. B. Liu, F. Wang*, and J. W. Liu*, Headgroup-Inversed Liposomes: Biointerfaces, Supported Bilayers and Applications. Langmuir, 2018, 34, 9937-6635 X. R. Liu♯, X. Q. Li♯, W. Xu^, X. H. Zhang, Z. C. Huang, F. Wang*, and J. W. Liu*, Sub-Angstrom Gold Nanoparticle/Liposome Interfaces Controlled by Halides. Langmuir, 2018, 34, 6628-6635 X. H. Zhang, A. Lopez, Y. B. Liu, F. Wang and J. W. Liu*, Interactions between citrate-capped gold nanoparticles and polymersome. Journal of Physics D: Applied Physics, 2018, 51, 244001

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