个人简介
2011.10-present Associate Professor, Nanjing University
2009.1-2011.8 Postdoctoral Researcher, University of South Florida
2008.1-2008.12 Postdoctoral Scholar, University of Iowa
2001-2007 PhD in Organic Chemitry, Shanghai Institute of Organic Chemistry, CAS
1997-2001 B.Sc. in Applied Chemistry, University of Science and Technology Beijing
副教授,博士生导师,课题组长。2001年毕业于北京科技大学应用化学系,获得学士学位,同年进入中国科学院上海有机化学研究所(金属有机化学国家重点实验室),师从侯雪龙研究员,2007年3月获得理学博士学位。2008年-2011年8月先后在美国艾奥瓦大学药学院和南佛罗里达大学化学系从事博士后研究。2011年10月,被聘为南京大学化学化工学院副教授,课题组长。2015年增选为博士生导师。2015年入选南京大学登峰人才支持计划(B层次)。主要开展手性合成化学和手性功能材料方面的研究。
研究领域
1.Asymmetric Synthesis
2.Chiral Functional Materials
近期论文
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Chen Liao, Yu Zhang, Shang-Hui Ye*, Wen-Hua Zheng*, Planar Chiral [2.2]Paracyclophane-Based Thermally Activated Delayed Fluorescent Materials for Circularly Polarized Electroluminescence. ACS Applied Materials & Interfaces 2021, 13, 25186-25192.
Shiru Yuan, Chen Liao, Wen-Hua Zheng*, [2.2]Paracyclophane-Based Isothiourea-Catalyzed Highly Enantioselective alpha-Fluorination of Carboxylic Acids. Organic Letters 2021, DOI: 10.1021/acs.orglett.1c01046.
Shan-Shui Meng, Peiyuan Yu, Yi-Zhe Yu, Yong Liang*, K. N. Houk*, Wen-Hua Zheng*, Computational Design of Enhanced Enantioselectivity in Chiral Phosphoric Acid-Catalyzed Oxidative Desymmetrization of 1,3-Diol Acetals. Journal of American Chemical Society 2020, 142, 8506-8513.
Hui Yang, Wen-Hua Zheng*, Chiral-Organotin-Catalyzed Kinetic Resolution of Vicinal Amino Alcohols. Angewandte Chemie International Edition 2019, 58, 16177-16180.
Hui Yang, Wen-Hua Zheng*, Parallel Kinetic Resolution of Unsymmetrical Acyclic Aliphatic syn-1,3-Diols. Organic Letters 2019, 21, 5197-5200.
Xiantao Fang, Zihang Deng, Wenhua Zheng, and Jon C. Antilla*. Catalytic One-Pot Double Asymmetric Cascade Reaction: Synthesis of Chlorinated Oxindoles and Geminal Diamines. ACS Catalysis 2019, 9, 1748-1752.
Yang Wang, Hang Yuan, Hongfei Lu*, Wen-Hua Zheng*. Development of Planar Chiral Iodoarenes Based on [2.2]Paracyclophane and Their Application in Catalytic Enantioselective Fluorination of β‑Ketoesters. Organic Letters 2018, 20, 2555-2558.
Shan-Shui Meng, Wu-Bang Tang, Wen-Hua Zheng*. Catalytically Enantioselective Synthesis of Acyclic α‑Tertiary Amines through Desymmetrization of 2‑Substituted 2‑Nitro-1,3-diols. Organic Letters 2018, 20, 518-521.
Hui Yang, Kou-Sen Cao, Wen-Hua Zheng*. A catalytic enantioselective approach to tetrol bearing vicinal all-carbon quaternary stereogenic centers. Chemical Communications 2017, 53, 3737-3740.
Shan-Shui Meng, Yong Liang, Kou-Sen Cao, Lufeng Zou, Xing-Bang Lin, Hui Yang, K. N. Houk*, Wen-Hua Zheng*. Chiral Phosphoric Acid Catalyzed Highly Enantioselective Desymmetrization of 2‑Substituted and 2,2-Disubstituted 1,3-Diols via Oxidative Cleavage of Benzylidene Acetals. Journal of American Chemical Society 2014, 136, 12249-12252.