张红雨 - 华中农业大学

个人简介

教育经历 1988.09-1992.07 山东大学生物系理学学士 1992.08-1997.01 中国科学院生物物理研究所理学博士主要职历 1997.02-1998.10 山东师范大学生命科学学院讲师 1998.11-2000.06 山东师范大学生命科学学院教授 2000.07-2009.01 山东理工大学生命科学学院教授、博导 2009.02-2014.06 华中农业大学生命科学技术学院教授、博导 2014.07至今华中农业大学信息学院院长（农业生物信息湖北省重点实验室主任、楚天学者特聘教授）

研究领域

生物信息学；系统生物学

近期论文

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1. Xie T., Yang Q.-Y., Wang X.-T., McLysaght A.*,Zhang H.-Y.* (2016) Spatial colocalization of human ohnolog pairs acts to maintain dosage-balance. Mol. Biol. Evol. 33: 2368-2375. (*corresponding authors) 2. Xiong M., Li B., Zhu Q., Wang Y.-X.,Zhang H.-Y.* (2014) Identification of transcription factors for drug-associated gene modules and biomedical implications. Bioinformatics 30: 305-309. (*corresponding author) 3. Peng C.*, Fu L.-Y., Dong P.-F., Deng Z.-L., Li J.-X., Wang X.-T.,Zhang H.-Y.* (2013) The sequencing bias relaxed characteristics of Hi-C derived data and implications for chromatin 3D modeling. Nucleic Acids Res. 41: e183. (*corresponding authors) 4. Wang Z.-Y.,Zhang H.-Y.* (2013) Rational drug repositioning by medical genetics. Nat. Biotechnol. 31: 1080-1082. (*corresponding author) 5. Jiang Y.-Y., Kong D.-X., Qin T., Li X., Caetano-Anollés G.,Zhang H.-Y.* (2012) The impact of oxygen on metabolic evolution: a chemoinformatic investigation. PLoS Comput. Biol. 8: e1002426. (*corresponding author) 6. Kim K. M., Qin T., Jiang Y.-Y., Chen L.-L., Xiong M., Caetano-Anollés D.,Zhang H.-Y.*, Caetano-Anollés G.* (2012) Protein domain structure uncovers the origin of aerobic metabolism and the rise of planetary oxygen. Structure 20: 67-76. (*corresponding authors) (Preview: Saito, M. A. Structure 2012, 20: 1-2) (Featured by Science News: http://news.sciencemag.org/sciencenow/2012/01/the-first-oxygen-users.html) 7. Wang M., Jiang Y.-Y., Kim K. M., Qu G., Ji H.-F., Mittenthal J. E.,Zhang H.-Y.*, Caetano-Anollés G.* (2011) A universal molecular clock of protein folds and its power in tracing the early history of aerobic metabolism and planet oxygenation. Mol. Biol. Evol. 28: 567-582. (*corresponding authors) 8. Zhu Q., Qin T., Jiang Y.-Y., Ji C., Kong D.-X., Ma B.-G.,Zhang H.-Y.* (2011) Chemical basis of metabolic network organization. PLoS Comput. Biol. 7: e1002214. (*corresponding author) 9.Zhang H.-Y.*, Chen L.-L., Li, X.-J., Zhang J. (2010) Evolutionary inspirations for drug discovery. Trends Pharmacol. Sci. 31: 443-448. (*corresponding author) 10. Ji H.-F., Li X.-J.,Zhang H.-Y.* (2009) Natural products and drug discovery. EMBO Rep. 10: 194-200. (*corresponding author) 11. Ji H.-F., Kong D.-X., Shen L., Chen L.-L., Ma B.-G.,Zhang H.-Y.* (2007) Distribution patterns of small-molecule ligands in the protein universe and implications for origin of life and drug discovery. Genome Biol. 8: R176. (*corresponding author) 12.Zhang H.-Y.*, Sun Y.-M., Wang X.-L. (2003) Substituent effects on O-H bond dissociation enthalpies and ionization potentials of catechols: a DFT study and its implications in rational design of phenolic antioxidants and elucidation of structure-activity relationships for flavonoid antioxidants. Chem. Eur. J. 9: 502-508. (*corresponding author) (ESI Top 1% paper)