个人简介
吴园,女,1989年1月出生。2018年6月于湖南大学化学化工学院分析化学专业获得理学博士学位,师从谭蔚泓院士,期间2014/09-2016/09受国家留学基金委公派前往美国佛罗里达大学留学2年。2018年7月加入华中农业大学理学院任讲师
研究领域
从事基于核酸适体和功能纳米材料的生物医学应用和生物传感器的快速分析检测研究,包括针对病毒感染细胞或针对病毒本身核酸适体的筛选及疾病标志物的鉴定、核酸适体生物传感器的构建、核酸适体介导的靶向癌症治疗和抗病毒治疗等内容。
近期论文
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1) Yuan Wu, Liqin Zhang, Sena Cansiz, Xiaobing Zhang*, and Weihong Tan*. Enhanced Targeted Gene Transduction: AAV2 Vectors Conjugated to Multiple Aptamers via Reducible Disulfide Linkages.
J. Am. Chem. Soc., 2018, 140, 2-5 (IF: 14.357,一区)
2) Quan Yuan#, Yuan Wu#, Jie Wang, Danqing Lu, Zilong Zhao, Tao Liu, Xiaobing Zhang, and Weihong Tan*. Targeted Bioimaging and Photodynamic Therapy Nanoplatform Using an Aptamer-Guided G-Quadruplex DNA Carrier and Near-Infrared Light. Angew. Chem. Int. Ed. 2013, 52, 13965 –13969. (IF:12.102,一区;文章中注明吴园和袁荃教授为共同第一作者)
3) Yuan Wu, Dan Li, Hao Liang, Fang Zhou, Shehua Xiao, Quan Yuan, Xiaobing Zhang*, Weihong Tan*. Versatile in-situ Synthesis of MnO2 Nanolayers on Upconverting Nanoparticles and Application for Activatable Fluorescence and MRI Imaging. Chemical Science, 2018, 9, 5427-5434 (IF: 9.063,一区)
4) Yuan Liu, Daniel L. Purich, Cuichen Wu, Yuan Wu, Tao Chen, , Liqin Zhang, Sena Cansiz, and Weihong Tan. Ionic Functionalization of Hydrophobic Colloidal Nanoparticles to Form Ionic Nanoparticles with Enzyme-like Properties. Journal of the American Chemical Society. 2015, 137 (47), 14952–14958 (影响因子:13.858,一区)
5) Tao Liu, Rong Hu, Yi-Fan Lv, Yuan Wu, Hao Liang, Shuang-Yan Huan, Xiao-Bing Zhang, Weihong Tan, and Ru-Qin Yu . An aggregated perylene-based Broad-spectrum, efficient and Label-free Quencher for Multiplexed Fluorescent Bioassays, Biosensors and Bioelectronics, 2014, 58, 320–325 (影响因子:7.78,一区)