个人简介
女,1983年生,四川省泸州市人,博士,副教授,药物化学教研室主任。
2009-2012 日本冈山大学大学院 博士研究生
2012-至今 西南医科大学药学院 药物化学教研室教师
研究领域
1.合成药物构效关系研究
2.手性药物的荧光对映选择性识别
近期论文
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1. Total Synthesis of Chiral Falcarindiol Analogues Using BINOL-Promoted Alkyne Addition to Aldehydes. Molecules 2016, 21: 112-123
2. Design, synthesis, and biological evaluation of artemisinin-indoloquinoline hybrids as potent antiproliferative agents. Molecules 2014, 19: 19021-19035.
3. Donepezil+propargylamine+8-hydroxyquinoline hybrids as new multifunctional metal-chelators, ChE and MAO Inhibitors for the potential treatment of Alzheimer’s disease. European Journal of Medicinal Chemistry, 2014, 80: 543-561.
4. Improved synthesis and reaction of 11-chloroneocryptolepines, strategic scaffold for antimalaria agent, and their 6-methyl congener from indole-3-carboxylate. Journal of Heterocyclic Chemistry, 2014, 51(4): 1106-1114.
5. Synthesis and in vitro antiproliferative activity of new 11-aminoalkylamino-substituted 5H- and 6H-indolo[2,3-b]quinolines; structure–activity relationships of neocryptolepines and 6-methyl congeners. Bioorganic & Medicinal Chemistry, 2012, 20(15): 4820-4829.