吴建明 - 西南医科大学

个人简介

（1981.01-），男，四川泸州人，博士（后），九三学社社员，教授，博士生导师，博士后导师，四川省学术和技术带头人后备人选，国家科技部专家库专家、四川省科技厅评审专家，中国药理学会中药与天然药物药理专委会青委会常务委员，四川省药理学会副秘书长、四川省心脑血管专委会副主任委员、四川省教育厅“药物筛选与成药性评价创新团队”负责人、泸州市学术技术带头人、Life Sciences，Rejuvenation Research，Drug Design, Development and Therapy，Molecules等多个SCI杂志审稿专家、四川省九三创新研究院专家。 2019.03-至今西南医科大学研究生院/药学院（副院长/教授） 2017.10-2019.03 西南医科大学科技处/药学院（科长/教授） 2014.06-2017.09 西南医科大学药学院（实验室主任/副教授） 2012.06-2014.06　四川大学华西药学院（博士后） 2006.02-2014.06　成都康弘药业集团国家级企业技术中心（副总监） 2003.05-2006.02　成都地奥药业集团药物研究所（新药研究员）

研究领域

1. 药物筛选与创新药物研究 2. 中药物质基础及分子机制研究

近期论文

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Jianming Wu, Tuoen Liu*, Zechary Rios, Qibing Mei, Xiukun Lin, Shousong Cao*. Heat shock proteins and cancer. Trends in Pharmacological Sciences. 2017, 38(3): 226-256. (IF: 12.797, JCR Q1 ) Jin-Feng Teng, Da-Lian Qin, Qi-Bing Mei, Wen-Qiao Qiu, Rong Pan, Rui Xiong, Ya Zhao, Betty Yuen-Kwan Law, Vincent Kam-Wai Wong, Yong Tang, Chong-Lin Yuc, Feng Zhang*, Jian-Ming Wu*, An-Guo Wu*. Polyphyllin VI, a saponin from Trillium tschonoskii Maxim. induces apoptotic and autophagic cell death via the ROS triggered mTOR signaling pathway in non-small cell lung cancer. Pharmacological Research, 2019, (147) 104396. (IF: 5.574, JCR Q1) Qu Li Ping, Li Di Di, Gao Xiao Ping, Li Yong Wei, Wu Jian Ming*, Zou Wen Jun*. Di’ao Xinxuekang Capsule, a Chinese Medicinal Product, Decreases Serum Lipids Levels in High-Fat Diet-Fed ApoE–/– Mice by Downregulating PCSK9. Frontiers in pharmacology, 2018, 9, article 1170. (IF: 3.845, JCR Q1) Chunlu Li†, Xiaoxuan Li†, Feihong Huang, Jing Yang, Anguo Wu, Long Wang, Dalian Qin, Wenjun Zou*, Jianming Wu*. Efficacy and Safety of Avatrombopag in Patients With Thrombocytopenia: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Frontiers in pharmacology, 2019, 7, article 829. (IF: 3.845, JCR Q1) Yaqi Kang†, Xinrui Jiang†, Dalian Qin, Long Wang, Jing Yang, Anguo Wu, Feihong Huang, Yun Ye*, Jianming Wu*. Efficacy and Safety of Multiple Dosages of Fostamatinib in Adult Patients With Rheumatoid Arthritis: A Systematic Review and Meta-Analysis. Frontiers in pharmacology, 2019, 8, article 897. (IF: 3.845, JCR Q1) Jiang, Xueqin; Liu, Zengjin; Yang, Youzhe; Li, Hao; Qi, Xiaoyi; Ren, Wen Xiu; Deng, Mingming; Lu, Muhan; Wu, Jianming*; Liang, Sicheng*. A mitochondria-targeted two-photon fluorescent probe for sensing and imaging pH changes in living cells. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 2019, 224, 117435. (IF: 2.931, JCR Q1) Xuefei Huang#,Jing Yang#, Sijin Yang, Shousong Cao, Dalian Qin, Ya Zhou,Xiaoli Li, Yun Ye*，Jianming Wu*. Role of tandospirone, a 5-HT1A receptor partial agonist, in the treatment of central nervous system disorders and the underlying mechanisms. Oncotarget, 2017, 1-16. (IF:5.168 ) Ya Zhao#, Yuan Zeng#, Anguo Wu, Chonglin Yu, Yong Tang, Xiuling Wang, Rui Xiong, Haixia Chen, Jianming Wu*, Dalian Qin*. Lychee Seed Fraction Inhibits Aβ(1-42)-Induced Neuroinflammation in BV-2 Cells via NF-κB Signaling Pathway. Frontiers in pharmacology, 2018, 9, article 380. (IF:4.4) Xiaoxuan Li#, Xuefei Huang#, Chongfei Bai, Dalian Qin, Shousong Cao, Qibing Mei, Yun Ye*, Jianming Wu*. Efficacy and Safety of Teneligliptin in Patients With Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Frontiers in pharmacology, 2018, 9, article 449. (IF:4.4) Jianming Wu# , Xiao Ke#, Wei Wang, Hongcheng Zhang, Na Ma, Wei Fu, Manxi Zhao, Xiaoping Gao, Xiaofeng Hao*, Zhirong Zhang*. Aloe-emodin suppresses hypoxia- induced retinal angiogenesis via inhibition of HIF-1α/VEGF pathway. International Journal of Biological Sciences. 2016,12(11): 1363-1371. (IF: 4.067)