齐琦 - 暨南大学 - 基础医学院

个人简介

2018.6-至今，暨南大学医学院药理系教授 2016.11-2018.5，埃默里大学医学院药理系化学生物学研发中心 Instructor (美国) 2015.3-2016.10，埃默里大学医学院药理系化学生物学研发中心Research Associate (美国) 2010.8-2015.2，埃默里大学医学院病理和实验医学系博士后(美国) 2009.8-2010.7，西弗吉尼亚大学医学院生理系伦道夫玛丽巴布癌症中心博士后(美国) 2006-2009，中国药科大学, 药理学博士学位 2003-2006，中国药科大学, 药理学硕士学位 1999-2003，郑州大学, 药学学士学位

研究领域

1、抗肿瘤化合物筛选，活性及机制研究 2、肿瘤相关蛋白功能及信号传导通路方面的研究 3、基于蛋白-蛋白相互作用的靶标的发现和研究

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Qi Q, Obianyo O, Du Y, Fu H, Li S, Ye K. Blockade of asparagine endopeptidase inhibits cancer metastasis. J Med Chem. 2017 Sep 14;60(17):7244-7255. Qi Q, Kang SS, Zhang S, Baker SJ, Fu H, Brat DJ, Ye K. Co-amplification of Phosphoinositide 3-kinase enhancer A and Cyclin-dependent kinas 4 Triggers Glioblastoma Progression. Oncogene. 2017 Aug 10;36(32):4562-4572. Qi Q, Li DY, Luo HR, Guan KL, Ye K. Netrin-1 exerts oncogenic activities through enhancing Yes-associated protein stability. Proc Natl Acad Sci U S A. 2015 Jun 9;112(23):7255-60. Qi Q, He K, Liu X, Pham C, Meyerkord C, Fu H. Ye K. Disrupting the PIKE-A/Akt interaction inhibits glioblastoma cell survival, migration, invasion, and colony formation. Oncogene. 2013 Feb 21;32(8):1030-40. Qi Q, Liu X, Daniel Brat, Ye K. Merlin sumoylation is required for its tumor suppressor activity. Oncogene. 2014 Oct 9;33(41):4893-903. He K, Qi Q, Chan CB, Xiao G, Liu X, Tucher-Burden C, Wang L, Mao H, Lu X, McDonald, F, Luo H, Fan Q, Weiss W, Sun S, Brat D, Wang L, Mao H, Fu H, Tao H, Ye K. Blockade of Glioma Proliferation Through Allosteric Inhibition of JAK2. Science signal. 2013 Jul 9;6(283):ra55. (Co-first author) Qi Q, He K, Yoo MH, Chan CB, Liu X, Zhang Z, Olson JJ, Xiao G, Wang L, Mao H, Fu H, Tao H, Ye K. Acridine yellow G blocks glioblastoma growth via dual inhibition of epidermal growth factor receptor and protein kinase C kinases. J Biol Chem. 2012 Feb 24;287(9):6113-27. Qi Q, Lu N, Li C, Zhao J, Liu W, You Q, Guo Q. Involvement of RECK in gambogic acid induced anti-invasive effect in A549 human lung carcinoma cells. Mol Carcinog. 2015 Jun;54 Suppl 1:E13-25. Qi Q, Gu H, Yang Y, Lu N, Zhao J, Liu W, Ling H, You QD, Wang X, Guo Q. Involvement of matrix metalloproteinase 2 and 9 in gambogic acid induced suppression of MDA-MB-435 human breast carcinoma cell lung metastasis. J Mol Med. 2008 Dec;86(12):1367-77. Qi Q, Lu N, Wang XT, Gu HY, Yang Y, Liu W, Li C, You QD, Guo QL. Anti-invasive effect of gambogic acid in MDA-MB-231 human breast carcinoma cells. Biochem Cell Biol. 2008 Oct;86(5):386-95. Qi Q, You Q, Gu H, Zhao L, Liu W, Lu N, Guo Q. Studies on the toxicity of gambogic acid in rats. J Ethnopharmacol. 2008 May 22;117(3):433-8. Li C, Lu N, Qi Q, Li F, Ling Y, Chen Y, Qin Y, Li Z, Zhang H, You Q, Guo Q. Gambogic acid inhibits tumor cell adhesion by suppressing integrin β1 and membrane lipid rafts-associated integrin signaling pathway. Biochem Pharmacol. 2011 Dec 15;82(12):1873-83. (Co-first author)