个人简介
2016.06-至今,暨南大学,副研究员
2013.01-2016.05,香港中文大学,博士后
2012.04-2012.06,Keio University (Japan),访问学者
2008-2012,香港中文大学,生理学,博士
2006-2008,中山大学,生理学,硕士
2002-2006,中山大学,应用生物技术,学士
近期论文
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1. Guo JH, Chen H, Ruan YC, Zhang XL, Zhang XH, Fok KL, Tsang LL, Yu MK, Huang WQ, Sun X, Chung YW, Jiang X, Sohma Y, Chan HC.Glucose-induced electrical activities and insulin secretion in pancreatic islet β-cells are modulated by CFTR.Nat Commun. 2014 Jul 15;5:4420. doi: 10.1038/ncomms5420.(影响因子:11.47)(总引用数-他引数)24-23
2. Ruan YC*,Guo JH*, Liu X, Zhang R, Tsang LL, Dong JD, Chen H, Yu MK, Jiang X, Zhang XH, Fok KL, Chung YW, Huang H, Zhou WL, Chan HC. Activation of the epithelial Na(+) channel triggers prostaglandin E(2) release and production required for embryo implantation. Nat Med. 2012 Jun 24. doi: 10.1038/nm.2771. (* 共同第一作者) (影响因子:30.357)(总引用数-他引数)62-58
3. Huang WQ*, Guo JH*, Zhang XH, Yu MK, Chung YW, Ruan YC, Chan HC.Glucose-Sensitive CFTR Suppresses Glucagon Secretion by Potentiating KATPChannels in Pancreatic Islet α Cells.Endocrinology.(影响因子:4.2859 )2017 Oct 1;158(10):3188-3199. doi: 10.1210/en.2017-00282.(* 共同第一作者)
4. Zhenqing Liu, Jinghui Guo, Yan Wang, Zhihui Weng, Biao Huang, Mei-Kuen Yu, Xiaohu Zhang, Ping Yuan, Hui Zhao, Wai-Yee Chan, Xiaohua Jiang and Hsiao-ChangChan. CFTR-β-catenin interaction regulates mouse embryonic stem cell differentiation and embryonic development.Cell Death Differ. 2017 Jan;24(1):98-110. doi: 10.1038/cdd.2016.118.(影响因子:8.218)
5. Chen H, Guo JH, Lu YC, Ding GL, Yu MK, Tsang LL, Fok KL, Liu XM, Zhang XH, Chung YW, Huang P, Huang H, Chan HC Impaired CFTR-dependent amplification of FSH-stimulated estrogen production in cystic fibrosis and PCOS.. J Clin Endocrinol Metab. 2012 Mar;97(3):923-32. Epub 2011 Dec 14. (影响因子:6.21)18-12
6. Chen H, Guo JH, Zhang XH, Chan HC Defective CFTR-regulated granulosa cell proliferation in polycystic ovarian syndrome.Reproduction. 2015 May;149(5):393-401. doi: 10.1530/REP-14-0368. Epub 2015 Feb 2.(影响因子:3.17)