个人简介
2012.03-2013.03,Hematology/Oncology, Children’s Hospital Los Angeles 访问学者
2011.03-2012.02,McArdle Laboratory for Cancer Research, University of Wisconsin-Madison 访问学者
2010.03-2011.03,Human Oncology and Pathogenesis Program (HOPP), Memorial Sloan-Kettering Cancer Center (MSKCC),NY, USA.访问学者
2008.10-至今,暨南大学医学院生物化学教研室,教授
2005.07-2008.09,暨南大学医学院生物化学教研室,副教授
2003.09-2005.07,南方医科大学基因工程研究所,分子生物学专业博士后, 副主任药师
2000.09-2003.07,暨南大学医学院血液病研究所,血液内科,获医学博士学位
1993.07-2000.09,东莞市亚洲制药有限公司,新药开发主管, 主管药师
1990.09-199.07,同济大学医学院 心血管内科,获硕士学位
1988.07-1990.09,安徽省庐江县人民医院内科,住院医师
1983.09-1988.07,安徽医科大学 临床医学系,获学士学位
研究领域
1、血液肿瘤非编码RNA(Non-Coding RNAs)功能研究
2、中医药系统生物学研究
3、小核酸药物筛选与肿瘤基因治疗
近期论文
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1.Gu C, Feng M, Yin Z, Luo X, Li Y, Li T,Wang R, Fei J*. RalA, a GTPase targeted by miR-181a, promotes transformation and progression by activating the Ras-related signaling pathway in chronic myelogenous leukemia. Oncotarget,2016 Mar 8. 7(15):20561-20573doi: 10.18632/oncotarget.7987. [Epub ahead of print](SCI, IF 6.359, A1-1区, corresponding author)
2. Feng M, Luo X, Gu C, Li Y, Zhu X, Fei J. * Systematic analysis of berberine-induced signaling pathway between miRNA clusters and mRNAs and identification of mir-99a~125b cluster function by seed-targeting inhibitors in multiple myeloma cells. RNA Biology 2015; 12(1):82-91. doi: 10.1080/15476286.2015.1017219.(SCI, IF 5.337, A1-2区, corresponding author)
3. Fei J*, Li Y, Zhu X, Luo X. miR-181a post-transcriptionally downregulates oncogenic RalA and contributes to growth inhibition and apoptosis in chronic myelogenous leukemia. PLoS One. 2012;7(3):e32834. Epub 2012 Mar 19. (SCI, IF 3.73, A1-2, corresponding author) 4. Zhu X, Li Y, Luo X, Fei J*. Inhibition of small GTPase RalA regulates growth and arsenic-induced apoptosis in chronic myeloid leukemia (CML) cell. Cell Signal. 2012 Jun; 24(6):1134-40. Epub 2012 Feb 3.(SCI, IF 4.304, A1-2区, corresponding author)
5.Li Y, Zhu X, Gu J, Dong D, Yao J, Lin C, Huang K, Fei J*. Anti-miR-21 Oligonucleotide Sensitizes Leukemic K562 Cells to Arsenic Trioxide By Inducing Apoptosis. Cancer Science.2010,101(4): 948–954 Epub 2010 Jan 7(SCI, IF 3.847, A1-2区, corresponding author)