个人简介
学习经历
2011-12 至 2015-02, 香港城市大学, 化学, 博士
2008-09 至 2011-07, 华南师范大学, 化学, 硕士
2004-09 至 2008-07, 湖南师范大学, 化学, 学士
工作经历
2022-10 至 今, 暨南大学, 化学与材料学院, 教授
2016-06 至 2022-10, 暨南大学, 化学与材料学院, 副教授
2015-02 至 2016-06, 香港城市大学, 生物与化学系, 研究实习员
2011-07 至 2011-12, 香港城市大学, 生物与化学系, 助理研究员
研究领域
金属配合物在调控化学体系和生命体系氧化还原平衡中发挥的功能和作用机理。针对肿瘤特性,设计具有氧化还原响应活性的金属药物,研究其在肿瘤诊疗及体系内催化的活性和机理
近期论文
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Mingkai Chen; Wenqiang Cao; Junping Wang; Fei Cai; Liwen Zhu; Li Ma ; Tianfeng Chen. Selenium Atom-Polarization Effect Determines TrxR-Specific Recognition of Metallodrugs. Journal of the American Chemical Society. 2022, 144(45): 20825-20833.
Liwen Zhu; Leung Chan; Junping Wang; Mingkai Chen; Fei Cai; Yuan Tian; Li Ma; Tianfeng Chen. Selenium-engineered bottom-up-synthesized lanthanide coordination nanoframeworks as efficiency X-ray-responsive radiosensitizers. Nano Research, 2022.
Yuequn Zhang; Mingkai Chen; Junping Wang; Fei Cai; Li Ma; Tianfeng Chen. Atom engineering-regulated in situ transition of Cu(I)-Cu(II) for efficiently overcoming cancer drug resistance. Science China Chemistry. 2022, 65(10): 1879-1884.
Hanjie Zhang; Yuequn Zhang; Jianrong Cao; Li Ma; Tianfeng Chen. Stable high-oxidationstate complex in situ Mn(v)–Mn(iii) transition to achieve highly efficient cervical cancer therapy. Chemical Communications. 2022, 58(23):3759-3762 .(封底论文)
Fei Cai; Kun Ye; Mingkai Chen; Yuan Tian; Peicong Chen; Hao Lin; Tianfeng Chen; Li Ma. High-dimensional zinc porphyrin nanoframeworks as efficient radiosensitizers for cervical cancer. Chinese Chemical Letters. 2022, 107945-107945.
Mingkai Chen; Xiaoting Huang; Huatian Shi; Jie Lai; Li Ma; Tai-Chu Lau; Tianfeng Chen. Cr(V)-Cr(III) in-situ transition promotes ROS generation to achieve efficient cancer therapy. Biomaterials. 2021,276:120991.
Zhennan Zhao; Pan Gao; Li Ma; Tianfeng Chen. A highly X-ray sensitive iridium prodrug for visualized tumor radiochemotherapy. Chemical Science. 2020, 11(15): 3780-3789.(封面论文,RSC专题亮点报道)
Li Ma; William W. Y. Lam; Po-Kam Lo; Kai-Chung Lau; Tai-Chu Lau. Ca(2+)-Induced Oxygen Generation by FeO4(2- )at pH 9–10. Angew Chem Int Ed. 2016,55(9): 3012-3016. (封底论文,热点论文)
Li Ma; Qian Wang; Wai-Lun Man; Hoi-Ki Kwong; Chi-Chiu Ko; Tai-Chu Lau. CeIV-Driven Water Oxidation Catalyzed by a Manganese(V) Nitrido Complex. Angew Chem Int Ed. 2015(17),54: 5246-5249.
Li Ma; Yi Pan; Wai-Lun Man; Hoi-Ki Kwong; William W. Y. Lam; Gui Chen; Kai-Chung Lau; Tai-Chu Lau. Highly Efficient Alkane Oxidation Catalyzed by [MnV(N)(CN)4]2- Evidence for [MnVII(N)(O)(CN)4]2- as an Active Intermediate. Journal of the American Chemical Society. 2014,136(21): 7680-7687.