翟红林 - 兰州大学 - 化学化工学院

研究领域

复杂体系中的多组分同时定性与定量分析、药物与蛋白质相互作用研究、药物分子设计目前主要从事复杂体系中的多组分同时定性与定量分析、实验条件优化、药物分子与蛋白质相互作用模拟、药物分子设计及计算机技术应用等相关的教学与科研工作。

近期论文

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B. Q. Li, J. Chen, J. J. Li, X. Wang, H. L. Zhai*. The application of Tchebichef moment method on the quantitative analysis of multiple compounds based on three-dimensional HPLC fingerprint spectra. Analyst, 2015, 140(2): 630-636. J. Chen, B. Q. Li, H. L. Zhai*, W. J. Lü, X. Y. Zhang. A practical application of wavelet moment method on the quantitative analysis of Shuanghuanglian oral liquid based on three-dimensional fingerprint spectra. Journal of Chromatography A, 2014, 1352: 55-61. H. L. Zhai*, B. Q. Li, Y. L. Tian, P. Z. Li, X. Y. Zhang. An application of wavelet moments to the similarity analysis of three-dimensional fingerprint spectra obtained by high-performance liquid chromatography coupled with diode array detector. Food Chemistry, 2014, 145: 625-631. H. L. Zhai*, Y. Y. Zhai, P. Z. Li, Y. L. Tian. A simple approach to the quantitative analysis using three-dimensional spectra based on the selected Zernike moments. Analyst, 2013, 138(2): 683-687. H. L. Zhai*, Z. J. Shan, R. N. Li, E Yu. Simultaneous quantitative analysis of three compounds using three-dimensional fluorescence spectra based on digital image techniques. Journal of Fluorescence, 2012, 22(4): 1013-1019. X. Y. Huang, Z. J. Shan, H. L. Zhai*, L. N. Li, X. Y. Zhang. Molecular design of anticancer drug leads based on three-dimensional quantitative structure-activity relationship. Journal of Chemical Information and Modeling, 2011, 51(8): 1999-2006. X. Y. Huang, Z. J. Shan, H. L. Zhai*, L. Shu, X. Y. Zhang. Study on the anticancer activity of coumarin derivatives by molecular modeling. Chemical Biology & Drug Design, 2011, 78(4): 651-658. H. L. Zhai*, X. H. Wang, X. Y. Huang, Z. J. Shan. The analysis of core promoter sequences based on their chemical features. Chemometrics and Intelligent Laboratory Systems, 2011, 107(2): 245-250. H. L. Zhai*, F. D. Hu, X. Y. Huang, J. H. Chen. The application of digital image recognition to the analysis of two-dimensional fingerprints. Analytica Chimica Acta, 2010, 657: 131-135. H. L. Zhai*, Y. T. Chang, C. C. Wu, J. S. Yu*. An approach to the elimination of inter-individual variability in tumor detection. Analyst, 2010, 135: 875-879.