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个人简介

1976年12月生于四川省成都。由四川省彭州中学保送入兰州大学化学系有机专业,2000年毕业于化学基地班并保送为硕博连读研究生,师从李卫东教授,主要从事萜类天然产物的全合成研究。2005年获兰州大学有机化学专业博士学位,同年留校继续从事科研和教学工作。2008年7月至2009年8月以博士后身份赴美国内华达大学(UNR)和加州大学圣芭芭拉分校(UCSB)进行研究,合作导师为Liming Zhang教授,主要从事Au催化下的均相有机反应研究及其在生物碱天然产物合成中的应用。目前已发表学术论文50余篇,引用数达2000余次。

研究领域

(1)过渡金属Ni催化的串联反应设计 (2)天然产物与药物分子的全合成 (3)小分子荧光探针的多样性合成

近期论文

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Jian Xiao, Xiao-Wei Cong, Gui-Zhen Yang, Ya-Wen Wang, Yu Peng*. Divergent Asymmetric Syntheses of Podophyllotoxin and Related Family Members via Stereoselective Reductive Ni-Catalysis, Org. Lett. 2018, 20, 1651-1654. Jian Xiao, Xiao-Wei Cong, Gui-Zhen Yang, Ya-Wen Wang, Yu Peng*. Stereoselective Synthesis of a Podophyllum Lignan Core by Intramolecular Reductive Ni-Catalysis, Chem. Commun. 2018, 54, 2040-2043. Muhammad Shar Jhahan Khan, Ya-Wen Wang,* Mathias O. Senge, Yu Peng*. Sensitive Fluorescence On-off Probes for the Fast Detection of a Chemical Warfare Agent Mimic, J. Hazard. Mater. 2018, 342, 10-19. Zhen-Hai Fu, Ya-Wen Wang,* Yu Peng*. Two Fluorescein-based Chemosensors for the Fast Detection of 2,4,6-Trinitrophenol (TNP) in Water, Chem. Commun. 2017, 53, 10524-10527. (Chemosensors and Molecular Logic themed issue) Ying-Xi Hua, Yongliang Shao, Ya-Wen Wang,* Yu Peng*. A Series of Fluorescent and Colorimetric Chemodosimeters for Selective Recognition of Cyanide Based on the FRET Mechanism, J. Org. Chem. 2017, 82, 6259-6267. Jian Xiao, Ya-Wen Wang, Yu Peng*. Nickel-Promoted Reductive Cyclization Cascade: A Short Synthesis of a New Aromatic Strigolactone Analogue, Synthesis 2017, 49, 3576-3581. (Special Topic: Advanced Strategies in Synthesis with Nickel) Zhen-Hai Fu, Xiao Han, Yongliang Shao, Jianguo Fang, Zhi-Hong Zhang, Ya-Wen Wang,* Yu Peng*. Fluorescein-based Chromogenic and Ratiometric Fluorescence Probe for Highly Selective Detection of Cysteine and Its Application in Bioimaging, Anal. Chem. 2017, 89, 1937-1944. (Highlighted by X-MOL) Zhen-Hai Fu, Lu-Bin Yan, Xiaolong Zhang, Fan-Fan Zhu, Xin-Long Han, Jianguo Fang, Ya-Wen Wang*, Yu Peng*. A Fluorescein-Based Chemosensor for Relay Fluorescence Recognition of Cu(II) Ions and Biothiols in Water and Its Applications to Molecular Logic Gate and Living Cell Imaging, Org. Biomol. Chem. 2017, 15, 4115-4121. (Inside Cover) Ai-Min Luo, Yongliang Shao, Ke-Jia Zhang, Ya-Wen Wang,* Yu Peng*. Syntheses of three terbium complexes as fluorescent probes and their application on the pH detection of routine urine test, Chin. Chem. Lett. 2017, 28, 2009-2013. (中国化学快报: 荧光探针专刊) Ya-Wen Wang,* Ying-Xi Hua, Hui-Hui Wu, Xin Sun, Yu Peng*. A Solvent-tuning Fluorescence Sensor for In(III) and Al(III) Ions and Its Bioimaging, Chin. Chem. Lett. 2017, 28, 1994-1996. (中国化学快报: 荧光探针专刊) Yu Peng*, Jian Xiao, Xiao-Bo Xu, Shu-Ming Duan, Li Ren, Yong-Liang Shao, Ya-Wen Wang. Stereospecific Synthesis of Tetrahydronaphtho[2,3-b]furans Enabled by a Nickel-Promoted Tandem Reductive Cyclization, Org. Lett. 2016, 18, 5170-5173. (Highlighted by Prof. Paul Knochel in Synfacts 2016, 12, 1296) Yu Peng*. Chapter 10: Lignans, Lignins, and Resveratrols in From Biosynthesis to Total Synthesis: Strategies and Tactics for Natural Products (Ed.: Alexandros L. Zografos), John Wiley & Sons, Inc, New Jersey, 2016, pp. 331–379. Ya-Wen Wang, Shun-Bang Liu, Wei-Jian Ling, Yu Peng*. A Fluorescent Probe for Relay Recognition of Homocysteine and Group IIIA Ions Including Ga(III), Chem. Commun. 2016, 52, 827-830. (Highlighted by X-MOL) Yu Peng*, Shu-Ming Duan, Ya-Wen Wang. Concise Synthesis of the DEFG Ring System in Rubriflordilactone B, Tetrahedron Lett. 2015, 56, 4509-4511. (Highlighted by X-MOL) Ya-Wen Wang, Shun-Bang Liu, Yan-Ling Yang, Peng-Zhi Wang, Ai-Jiang Zhang, Yu Peng*. A Terbium(III)-Complex-Based On-Off Fluorescent Chemosensor for Phosphate Anions in Aqueous Solution and Its Application in Molecular Logic Gates, ACS Appl. Mater. Interfaces 2015, 7, 4415-4422. Yan-Ling Yang, Fu-Ming Zhang, Ya-Wen Wang,* Bao-Xin Zhang, Ran Fang, Jian-Guo Fang, Yu Peng*. An Iminocoumarin Sulfonamide Based Turn-On Fluorescent Probe for the Detection of Biothiols in Aqueous Solution, Chem.-Asian. J. 2015, 10, 422-426. Long Luo, Jian-Jian Zhang, Wei-Jian Ling, Yong-Liang Shao, Ya-Wen Wang, Yu Peng*. Unified Synthesis of (-)-Folicanthine and (-)-Ditryptophenaline Enabled by a Nickel-Mediated Reductive Dimerization at Room Temperature, Synthesis 2014, 46, 1908-1916. (Special Topic: Copper and Nickel Catalysis). Yan-Ling Yang, Ya-Wen Wang, Yu Peng*. A Bifunctional, Colorimetric and Fluorescent Probe for Recognition of Cu2+ and Hg2+ and Its Application in Molecular Logic Gate, Sci. China Chem. 2014, 57, 289-295. (Special Issue: The Frontiers of Chemical Biology and Synthesis for the 9th SINO-US Chemistry Professors Conference) Yu Peng*, Xiao-Bo Xu, Jian Xiao, Ya-Wen Wang. Nickel-Mediated Stereocontrolled Synthesis of Spiroketals via Tandem Cyclization-Coupling of β-Bromo Ketals and Aryl Iodides, Chem. Commun. 2014, 50, 472-474. Yan-Ling Yang, Ya-Wen Wang, Dong-Zhu Duan, Ai-Jiang Zhang, Jian-Guo Fang, Yu Peng*. Off–On–Off Fluorescent Chemosensor for pH Measurement with a Terbium(III) Complex Based on a Tripodal Salicylic-acid Derivative, Org. Biomol. Chem. 2013, 11, 6960-6966.

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