翟宏斌 - 兰州大学 - 化学化工学院

研究领域

天然产物的全合成研究；新颖实用的合成方法的探索；针对人类重要疾病的新颖杂环化合物的设计与合成

近期论文

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Cheng, B.; Wu, F.; Yang, X.; Zhou, Y.; Wan, X.; Zhai, H.* Efficient Total Synthesis of Marine Alkaloid (–)-Nakadomarin A Chem. Eur. J. 2011 (Chem.201102281, in press; Total Synthesis of Natural Products). Yu, F.; Li, G.; Gao, P.; Gong, H.; Liu, Y.; Wu, Y.; Cheng, B.; Zhai, H.* Concise Synthesis of the Oxapentacyclic Core of Cortistatin A Org. Lett. 2010, 12, 5135 (Synthetic Studies of Natural Products). Zhang, W.; Yang, X.; Chen, W.; Xu, X.; Li, L.; Zhai, H.*; Li, Z.* Design, Multicomponent Synthesis, and Bioactivities of Novel Neonicotinoid Analogues with 1,4-Dihydropyridine Scaffold J. Agric. Food Chem. 2010, 58, 2741 (Medicinal Chemistry). Xu, Q.; Cheng, B.; Ye, X.; Zhai, H.* SmI2–Mediated Carbon–Carbon Bond Fragmentation in α-Aminomethyl Malonates Org. Lett. 2009, 11, 4136 (Synthetic Methodology). Lin Hu, L.; Zhang, L.; Zhai, H.* Syntheses and Configuration Determination of ( )-Villatamines A and B, Two Marine Natural Products J. Org. Chem. 2009, 74, 7552 (Total Synthesis of Natural Products). Li, G.; Yang, X.; Zhai, H.* Total Synthesis of (–)-5,6-Dihydrocineromycin B J. Org. Chem. 2009, 74, 1356 (Total Synthesis of Natural Products). Gao, P.; Xu, P.-F.; Zhai, H.* Expeditious Construction of ( )-Mintlactone via Intramolecular Hetero-Pauson-Khand Reaction J. Org. Chem. 2009, 74, 2592 (Total Synthesis of Natural Products). Deng, H.; Yang, X.; Tong, Z.; Li, Z.; Zhai, H.* Expedient Synthesis of the Tetracyclic Core of ent-Nakadomarin A Org. Lett. 2008, 10, 1791 (Synthetic Studies of Natural Products). Yang, X.; Zhai, H.;* Li, Z.* Enantiocontrolled Synthesis of (–)-9-epi-Pentazocine and (–)-Aphanorphine Org. Lett. 2008, 10, 2457 (Total Synthesis of Natural Products & Medicinal Chemistry). Sang, Y.; Zhao, J.; Jia, X.; Zhai, H.* Asymmetric Synthesis of ( )-Pyrido[3,4-b]homotropane J. Org. Chem. 2008, 73, 3589 (Medicinal Chemistry). Gao, P.; Liu, Y.; Zhang, L.; Xu, P.-F.; Wang, S.; Lu, Y.; He, M.; Zhai, H.* “Total Synthesis of Indole Alkaloid (±)-Subincanadine F via SmI2-Mediated Ring-Opening and Bridge-Forming Mannich Reaction” J. Org. Chem. 2006, 71, 9495 (Total Synthesis of Natural Products). Liu, Y.; Luo, S.; Fu, X.; Fang, F.; Zhuang, Z.; Xiong, W.; Jia, X.; Zhai, H.* “Facile Construction of the Pentacyclic Framework of Subincanadine B. Synthesis of 20-Deethylenylated Subincanadine B and 19,20-Dihydrosubincanadine B” Org. Lett. 2006, 8, 115 (Synthetic Studies of Natural Products). Zhang, W.; Luo, S.; Fang, F.; Chen, Q.; Hu, H.; Jia, X.; Zhai, H.* “Total Synthesis of Absinthin” J. Am. Chem. Soc. 2005, 127, 18 (Total Synthesis of Natural Products). Ye, W.; Cai, G.; Zhuang, Z.; Jia,X.; Zhai, H.* “One-Step Assembly of Functionalized γ-Butyrolactones from Benzoins or Benzaldehydes via an N-Heterocyclic Carbene-Mediated Tandem Reaction” Org. Lett. 2005, 7, 3769 (Synthetic Methodology).