研究领域
自由基化学和自由基生物学、生物有机和化学生物学
目前的兴趣集中于生物抗氧化剂的结构修饰及其活性机制和基于生物抗氧化剂的癌预防药物分子设计。
近期论文
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Antioxidant activity of a-pyridoin and its derivatives: possible mechanism, Org. Biomol. Chem. 2010, 8, 1058-1063.
Antioxidant capacity of curcumin-directed analogues: Structure-activity relationship and influence of microenvironment, Food Chem., 2010, 119, 1435-1442.
Hydroxycinnamic acids as DNA-cleaving agents in the presence of Cu(II) ions: Mechanism, structure-activity relationship and biological implication, Chem. Eur. J., 2009, 15, 12889-12899.
Radical-Scavenging Activity and Mechanism of Resveratrol-Oriented Analogues: Influence of the Solvent, Radical, and Substitution, J. Org. Chem., 2009, 74, 5025-5031.
4,4’-Dihydroxy-trans-stilbene, a resveratrol analogue, exhibited enhanced antioxidant activity and cytotoxicity, Bioorg. Med. Chem., 2009, 17, 2360-2365.
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