个人简介
教育背景、工作经历
2015-至今 兰州大学萃英学院执行院长
2009-2015 兰州大学教务处处长
2003-至今 兰州大学化学化工学院、功能有机分子化学国家重点实验室,教授
2003-2004 日本名古屋大学物质材料科学国际研究中心(K. Tatsumi合作教授),访问教授
1999-2001 台湾中兴大学,博士后(陆大荣教授)
1996-1998 兰州大学,理学博士(张自义教授)
1992-1994 兰州大学,理学硕士(吴绍祖教授)
1983-1987 兰州大学,化学系有机化学专业,理学学士(李瑜教授)
研究领域
1)α-氨基酸的不对称合成及方法研究;
2)有机小分子催化的不对称串联反应的研究;
3)天然产物结构导向的有机小分子催化反应的研究;
4)可见光催化的有机反应研究;
5) 新型可见光催化剂的设计与应用;
6)新型浮选剂的研发。
近期论文
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Wang, Y.; Lu, H.;Xu, P.-F.* Asymmetric Catalytic Cascade Reactions for Constructing Diverse Sca?olds and Complex Molecules. Acc. Chem. Res. 2015, 48, 1832.
Luo, Y.-C.; Zhang, H.-H.; Wang, Y.; Xu, P.-F.* Synthesis of α-Amino Acids Based on Chiral Tricycloiminolactone Derived from Natural (+)-Camphor. Acc. Chem. Res. 2010,43, 1317.
Gu, Y.; Wang, Y.; Yu, T.-Y.; Liang Y.-M.*;Xu, P.-F.* Rationally Designed Multifunctional Supramolecular Iminium Catalysis: Direct Vinylogous Michael Addition of Unmodified Linear Dienol Substrates. Angew.Chem. Int. Ed. 2014, 53, 14128.
Wang,Y.; Yu,T.-Y.; Zhang,H.-B.; Luo,Y.-C.;Xu, P.-F.* Hydrogen-Bond-Mediated Supramolecular Iminium Ion Catalysis. Angew.Chem. Int. Ed. 2012, 51, 12339.5. Wang, Y; Han, R.-G.; Zhao, Y.-L.; Yang, S.; Dixon, D. J.; Xu, P.-F.* AsymmetricOrganocatalytic Relay Cascades: Catalyst-Controlled Stereoisomer Selection in the Synthesis of Functionalized Cyclohexanes. Angew. Chem. Int. Ed. 2009, 48, 9834
Lu, H.; Liu, J.-Y.; Li, C.-G.; Lin, J.-B.; Liang Y.-M.andXu P.-F.* A new chiral C1-symmetric NHC-catalyzed addition to α-aryl substituted α,β-disubstitutedenals: enantioselective synthesis of fully functionalized dihydropyranones. Chem. Commun. 2015,51, 8385.
Lin, J.-B.; Xu,S.-M.; Xie, J.-K.; Li, H.-Y.;Xu, P.-F.* An organocatalytic Michael-cyclization cascade of 4-oxa-α,β-unsaturated carboxylic acids with aldehydes: facile synthesis of chiral γ-lactols and trisubstituted γ-lactones. Chem. Commun. 2015,51, 3596.
Gao,T.-P.; Lin, J.-B.; Hu, X.-Q.; Xu P.-F.* A catalytic asymmetric hetero-Diels–Alder reaction of olefinicazlactones and isatins: facile access to chiral spirooxindoledihydropyranones. Chem. Commun. 2014, 50, 8934.
Yu,T.-Y.; Wang,Y.; Hu,X.-Q.;Xu P.-F.* Triphenylphosphine oxide-catalyzed stereoselective poly- and dibromination of unsaturated compounds. Chem. Commun. 2014, 50, 7817.
Tian, L.; Xu, G.-Q.; Li, Y.-H.; Liang Y.-M.;*Xu P.-F.* An efficient strategy for the synthesis of polysubstitutedchromeno[4,3-b]pyrrolidine derivatives. Chem. Commun. 2014, 50, 2428.
Zhao,Y.-L.;Wang, Y.; Hu,X.-Q.;Xu, P.-F.* Merging organocatalysis with transition metal catalysis and using O2 as the oxidant for enantioselective C–H functionalization of aldehydes. Chem. Commun. 2013, 49, 7555.
Tian,L.; Hu,X.-Q.; Li,Y.-H.;Xu, P.-F.* Organocatalytic asymmetric multicomponent cascade reaction via 1,3-proton shift and [3+2] cycloaddition: an efficient strategy for the synthesis of oxindole derivatives. Chem. Commun. 2013, 49, 7213.
Duan,G.-J.; Ling, J.-B.; Wang, W.-P.; Luo, Y.-C.;Xu, P.-F.* Organocatalytic formal [2+2] cycloaddition initiated by vinylogousFriedel–Crafts alkylation: enantioselective synthesis of substituted cyclobutane derivatives. Chem. Commun. 2013, 49, 4625.
Zhao, S.; Zhao, Y.-Y.; Lin, J.-B.;Xie, T.; Liang, Y.-M.*; Xu, P.-F.* Organocatalyzed Asymmetric Vinylogous Allylic–Allylic Alkylation of Morita–Baylis–Hillman Carbonates with OlefinicAzlactones: Facile Access to Chiral Multifunctional α-Amino Acid Derivatives. Org. Lett. 2015, 17, 3206.
Zhang, H.-H.; Luo Y.-C. *; Wang, H.-P.; Chen, W.; Xu, P.-F.* TiCl4 Promoted Formal [3 + 3] Cycloaddition of Cyclopropane 1,1-Diesters with Azides: Synthesis of Highly Functionalized Triazinines and Azetidines. Org. Lett. 2014, 16, 4896.
Zhao, Y.-L.; Wang, Y.; Cao, J.; Liang, Y.-M.*;Xu, P.-F.* Organocatalytic Asymmetric Michael–Michael Cascade for the Construction of Highly Functionalized N-Fused Piperidinoindoline Derivatives. Org. Lett. 2014, 16, 2438.
Zhao, S.; Lin, J.-B.; Zhao, Y.-Y.; Liang, Y.-M.*;Xu, P.-F.* Hydrogen-Bond-Directed Formal [5 + 1] Annulations of Oxindoles with Ester-Linked Bisenones: Facile Access to Chiral Spirooxindole δ-Lactones. Org. Lett. 2014, 16, 1802.