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研究领域

自上世纪八十年代以来一直致力于O, N, S等杂原子的有机配体和配合物的合成、结构和生物活性研究。合成了巯基和硒基氧化吡啶类单、双核配合物,探讨了结构与性质之间的关系。目前通过抑菌和抗肿瘤实验初步研究证明,该类配合物对胃癌、肺癌等癌细胞具有极强的抑制和杀灭效果,其有效浓度可达到ppm级。

近期论文

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Bis(2-ethyl-3-hydroxy-4 –pyra- nonato)diiodotin(Ⅳ) acetonitrile solvate,Acta Cryst.,1999, C55, 2051-3 Solubilities of iron(Ⅲ) complexes of 3-hydroxy-2-ethyl- 4-pyranone and of 3- hydroxy-1, 2-dimethyl-4-pyridinone in aqueous salt solutions,Trans. Met. Chem., 2002, 27, 239-43, Three N-aryl-substitutied 3-hydroxy-pyridin-4-one,Acta Cryst.,1998, C54, 430-3 Synthesis and crystal structure of tri(4-(3-hydroxy-2-ethyl-4-pyridinone- 1-yl)-aniline condensation salicylaldehydato) monohydrate- tricopper(II) dimethylformamide Monohydrate solvate,Chinese J. Struct. Chem. 2003, 22, 681-6 Synthesis and crystal structure of tris(N-p-methylphenyl-3-hydroxy-2-ethyl- 4-pyridinonato)iron(Ⅲ),Chinese J. Struct. Chem. 2001, 20, 466-9 Synthesis and crystal structure of cis-bis(3-hydroxy-2-ethyl-4- pyranonato) dioxomolybdenum(VI),Chinese J. Struct. Chem. 2003, 22, 573-6 Crystal structure of (1R,4R;1S, 4S)-2-amino-3-cyano-1-diphenyl-2- cyclopentene-1-ol. Chinese J. Struct. Chem. 1998, 17, 70-3 N-芳基-2-乙基-3-羟基-4-吡啶酮的微波合成,有机化学, 2003, 23, 89-91 1-(4-Aminophenyl)-2-ethyl-3-hydroxy-1,4-dihydropyridin-4-one mono- hydrate,Acta Cryst. 2007, E63, o2614-2615

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