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个人简介

教育经历 2001/09-2006/06,华中农业大学动物科技学院,动物遗传育种与繁殖,博士 1997/09-2001/06,河北农业大学动物科技学院,畜牧,学士 主要职历 2019/12 - 至今,华中农业大学,水产学院,教授 2012/05 - 2013/06,美国哈佛大学,医学院,访问学者 2011/01 - 至今,华中农业大学,水产学院,博士生导师 2009/01 - 2019/11,华中农业大学,水产学院,副教授 2006/07 - 2008/12,华中农业大学,水产学院,讲师

研究领域

分子遗传与鱼类育种

近期论文

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1. Huang CX, Huang Y, Duan XK, Zhang M, Tu JP, Liu JX, Liu H, Chen TS, Wang WM, Wang HL*. Zebrafish miR-462-731 regulates hematopoietic specification and pu.1-dependent primitive myelopoiesis. Cell Death Differ. 2018 Nov 20. doi: 10.1038/s41418-018-0234-0 (IF:8.0) 2. Chen N, Huang CX, Huang CH, He Y, Chen TS, Zhu DM, Liu H, Wang WM, Wang HL*. The molecular characterization, expression pattern and alternative initiation of Hif prolyl hydroxylase Phd1. Gene, 2018, 678: 219-225 (IF:2.415) 3. He Y, Huang CX, Chen N, Wu M, Huang Y, Liu H, Tang R, Wang WM, Wang HL*.The zebrafish miR-125c is induced under hypoxic stress via hypoxia-inducible factor 1α and functions in cellular adaptations and embryogenesis.Oncotarget. 2017, 8 (43) : 73846-73859 (IF:5.165) 4. Chen N, Wu M, Wang HJ, Liu H, Wang WM, Wang HL*. Effects of Acute Hypoxia and Reoxygenation on Physiological and Immune Responses and Redox Balance of Wuchang Bream (Megalobrama amblycephala Yih, 1955), Front. Physiol., 2017, 8:375 (IF:4.134) 5. Chen BX, Yi SK, Wang WF, He Y, Huang Y, Gao ZX, Liu H, Wang WM, Wang HL*.Transcriptome comparison reveals insights into muscle response to hypoxia in blunt snout bream (Megalobrama amblycephala). Gene. 2017, 624:6-13. (IF:2.415) 6. Huang CX, Chen N, Wu XJ, He Y, Huang CH, Liu H, Wang WM, Wang HL*. Zebrafish let-7b acts downstream of hypoxia-inducible factor-1α to assist in hypoxia-mediated cell proliferation and cell cycle regulation. Life Sciences, 2017, 171:21-29 (IF:2.936) 7. Huang CH, Chen N, Huang CX, Zhang B, Wu M, He L, Liu H, Tang R, Wang WM, Wang HL*, Involvement of miR-462/731 cluster in hypoxia response in Megalobrama amblycephala. Fish Physiol Biochem, 2017, 43(3):863-873 (IF:1.647) 8. Wu M, Chen N, Huang CX, He Y, Zhao YZ, Chen XH, Chen XL*, and Wang HL*. Effect of Low Temperature on Globin Expression, Respiratory Metabolic Enzyme Activities, and Gill Structure of Litopenaeus vannamei. Biochemistry (Moscow), 2017, 82(7): 844-851 (IF:1.537) 9. Huang CX, Chen N, Wu XJ, Huang CH, He Y, Tang R, Wang WM, Wang HL*. The zebrafish miR-462/miR-731 cluster is induced under hypoxic stress via hypoxia-inducible factor 1α and functions in cellular adaptations. FASEB J. 2015, 29(12): 4901-13 (IF:5.043) 10. Chen N, Wang WM, Wang HL*. An efficient full-length cDNA amplification strategy based on bioinformatics technology and multiplexed PCR methods. Sci Rep, 2016,5:19420. (IF:5.578) 11. Zhang B, Chen N, Huang CH, Huang CX, Chen BX, Liu H, Wang WM, Wang HL*, Molecular response and association analysis of Megalobrama amblycephala fih-1 with hypoxia, Mol Genet Genomics, 2016, 291(4): 1615-24 (IF: 2.728) 12. Chen N, Huang CH, Liu H, Chen BX, Wang WM, Wang HL*. Alternative splicing transcription of Megalobrama amblycephala HIF prolyl hydroxylase PHD3 and up-regulation of PHD3 by HIF-1α. Biochem Biophys Res Commun, 2016, 469(3): 737-42. (IF:2.297) 13. Wang HJ, Huang CX, Chen N, Zhu KC, Chen BX, Wang WM, Wang HL*. Molecular characterization and mRNA expression of HIF-prolyl hydroxylase-2 (phd2) in hypoxia-sensing pathways from Megalobrama amblycephala. Comp Biochem Physiol B Biochem Mol Biol. 2015, 186:28-35 (IF:1.551) 14. Zhu KC, Yu DH, Zhao JK, Wang WM, Wang HL*. Morphological analysis and muscle-associated gene expression during different muscle growth phases of Megalobrama amblycephala. Genet Mol Res. 2015, 14(3):11639-51. (IF:0.775) 15. Xu MX, Huang CX, Chen N, Wu XJ, Zhu KC,Wang WM, Wang HL*, Sequence analysis and expression regulation of rbp4 by 9-cis-RA in Megalobrama amblycephala, Fish Physiol Biochem. 2015, 41(2):437-47 (IF:1.622) 16. Chen N, Wan XL, Huang CX, Wang WM, Liu H, Wang HL*. Study on the immune response to recombinant Hsp70 protein from Megalobrama amblycephala, Immunobiology, 2014, 219, 850–858 (IF:3.044) 17. Zhang J, Wei XL, Chen LP, Chen N, Xu MX, Huang C, Wang WM, Wang HL*. Characterization of a novel CC chemokine CCL4 in immune response induced by nitrite and its expression differences among three populations of Megalobrama amblycephala. Fish & shellfish immunology. 2014, 38(1), 88-95 (IF:2.674) 18. Zhu KC, Wang HL*, Wang HJ, Yasmeen Gul, Yang M, Zeng C, Wang WM, Characterization of muscle morphology and satellite cells, and expression of muscle-related genes in skeletal muscle of juvenile and adult Megalobrama amblycephala, Micron, 2014, 64, 66–75 (IF:1.988) 19. Zhu KC, Chen LP, Zhao JK, Wang HJ, Wang WM, Li Z, Wang HL*.Molecular characterization and expression patterns of myogenin in compensatory growth of Megalobrama amblycephala.Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology. 2014,170, 10–17 (IF:1.551) 20. Huang CX, Wei XL, Chen N, Zhang J, Chen LP, Wang WM, Li JY, Wang HL*.Growth differentiation factor 9 of Megalobrama amblycephala: molecular characterization and expression analysis during the development of early embryos and growing ovaries. Fish Physiol Biochem. 2014, 40(1):193-203 (IF:1.622)

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