当前位置: X-MOL首页全球导师 国内导师 › 李广宇

个人简介

教育经历 2005/9 - 2010/7,中国科学院水生生物研究所,水生生物学,博士, 2001/9 - 2005/7,华中师范大学,生物技术,学士 主要职历 2010/7-2012/12,华中农业大学,水产学院,讲师 2013/1-2018/11,华中农业大学,水产学院,副教授 2016/3-2017/3,加州大学戴维斯分校,访问学者 2018/11 - 至今,华中农业大学,水产学院,教授,博士生导师

研究领域

(1)毒理生态学:以斑马鱼为模式生物,评价环境污染物对鱼类的毒性效应; (2)水环境监测与评价:监测和评估人类活动对水环境的质与量的影响、水资源开发引起的环境负效应

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

Wu Q, Yan W, Liu CS, Hung TC, Li GY*. 2018. Parental transfer of titanium dioxide nanoparticle aggravated MCLR-induced developmental toxicity in zebrafish offspring Environmental Science: Nano, 5, 2952-2965. (影响因子 7.704;中科院一区) Cheng HC, Wu Q, Yan W, Liu CS, Hung TC, Li GY*. 2018. Adverse reproductive performance in zebrafish with increased bioconcentration of microcystin-LR in the presence of titanium dioxide nanoparticle. Environmental Science: Nano, 5:1208-1217. (影响因子 7.704;中科院一区) Wu Q, Yan W*, Liu CS, Hung TC, Li GY*. 2019. Co-exposure with titanium dioxide nanoparticles exacerbates MCLR-induced brain injury in zebrafish. Science of The Total Environment, 693, 133540. (影响因子 5.578;JCR一区) Wu Q, Yan W, Cheng HC, Liu CS, Hung TC, Guo XC, Li GY*. 2017. Parental transfer of microcystin-LR induced transgenerational effects of developmental neurotoxicity in zebrafish offspring. Environmental Pollution 231:471-478. (影响因子 5.714;JCR一区) Cheng HC, Yan W, Wu Q, Liu CS, Gong XY, Hung TC, Li GY*. 2017. Parental exposure to microcystin-LR induced thyroid endocrine disruption in zebrafish offspring, a transgenerational toxicity. Environmental Pollution 230, 981–988. (影响因子 5.714;JCR一区) Li GY#, Ye HK, Su GY, Han ZH, Xie CX, Zhou BS, Letcher RJ, Giesy JP, Yu HX, Liu CS. 2017. Establishment of a three-step method to evaluate effects of chemicals on development of zebrafish embryo/larvae. Chemosphere 186, 209-217. (影响因子 5.108;JCR一区) Wu Q, Yan W, Liu CS, Li L, Yu L, Zhao SJ, Li GY*. 2016. Microcystin-LR exposure induces developmental neurotoxicity in zebrafish embryo. Environmental Pollution 213, 793-800. (影响因子 5.714;JCR一区) He J #, Li GY #, Chen J #, Lin J, Zeng C, Chen J, Deng J, Xie P*. 2017. Prolonged exposure to low‑dose microcystin induces nonalcoholic steatohepatitis in mice: a systems toxicology study. Archives of Toxicology 91, 465-480. (影响因子 5.901;中科院一区) Li GY#, Yan W, Dang Y, Li J, Liu CS, Wang J*. 2015. The role of calcineurin signaling in microcystin-LR triggered neuronal toxicity. Scientific Reports 5:11271. (影响因子 5.228;JCR二区) Li J, Giesy JP, Yu L, Li GY*, Liu CS*. 2015. Effects of tris(1,3-dichloro-2-propyl) phosphate (TDCPP) in Tetrahymena Thermophila: targeting the ribosome. Scientific Reports 5:10562. (影响因子 5.228) Li G, Cai F, Yan W, Li CR, Wang JH*. 2012. A proteomic analysis of MCLR-induced neurotoxicity: implications for Alzheimer's disease. Toxicological Sciences 127: 485-495. 2012b. (影响因子5.019;JCR一区) Xie L, Yan W, Yu L, Wang J, Li GY*, Chen N*, Alan DS. 2015. Microcystin-RR exposure results in growth impairment by disrupting thyroid endocrine in zebrafish larvae. Aquatic Toxicology 164:16-22. (影响因子 3.884;JCR一区) Zhao SJ, Li G*, Chen J*. 2015. A proteomic analysis of prenatal transfer of microcystin-LR induced neurotoxicity in rat offspring. Journal of Proteomics 114: 197-213. (影响因子 3.867;JCR二区) Zeng C, Sun H, Xie P, Wang JH, Zhang GR, Chen N, Yan W*, Li GY*. 2014. The role of apoptosis in MCLR-induced developmental toxicity in zebrafish embryos. Aquatic Toxicology 149: 25-32. (影响因子 3.884;JCR一区) Li GY, Yan W, Cai F, He Y, Chen N, Wang JH*.2014. Spatial learning and memory impairment and pathological change in rats induced by acute exposure to microcystin-LR. Environmental Toxicology 29: 261-268. (影响因子 3.193) Li G, Yan W, Qiao Q, Chen J, Cai F, He Y, Zhang X*. 2012. Global effects of subchronic treatment of microcystin-LR on rat splenetic protein levels. Journal of Proteomics 77: 383-393. (影响因子 3.867) Liu CS, Yan W, Zhou BS, Guo YY, Liu HL, Yu HX, Giesy JP, Wang JH, Li GY*, Zhang XW*. Characterization of a bystander effect induced by the endocrine-disrupting chemical 6-propyl-2-thiouracil in zebrafish embryos. Aquatic Toxicology 118: 108-115. 2012. [影响因子 3.72] Yan W, Zhou Y, Yang J, Wang JH, Chen J*, Li GY*. Waterborne exposure to microcystin-LR alters thyroid hormone levels and gene transcription in the hypothalamic-pituitary-thyroid axis in zebrafish larvae. Chemosphere 87(11): 1301-1307. 2012. [影响因子 3.15] Li GY, Chen J, Xie P*, Jiang Y, Wu LY, Zhang XZ. Protein profiles in zebrafish (Danio rerio) embryos exposed to microcystin-LR. Proteomics 11:2003-2018. 2011. [影响因子 4.82] Li GY, Shen D, Liang XF*, He Y, He S. Effects of malachite Green on the mRNA expression of detoxification-related genes in Nile tilapia (Oreochromis niloticus) and other major Chinese freshwater fishes. Environmental Toxicology 28: 137-145. 2013. [IF 2.40] Li GY, Xie P*, Li HY, Hao L, Xiong Q, Qiu T. Acute effects of microcystins on the transcription of 14 glutathione S-transferase isoforms in Wistar rat. Environmental Toxicology 26:187-194. 2011. [IF 1.83] Li GY, Xie P*, Li HY, Hao L, Xiong Q, Qiu T, Liu Y. Involment of p53, Bax, and Bcl-2 pathway in microcystins-induced apoptosis in rat testis. Environmental Toxicology 26:111-117. 2011. [IF 1.83] Li GY, Xie P*, Li HY, Chen J, Hao L, Xiong Q. Quantitative profiling of mRNA expression of glutathione S-transferase superfamily genes in various tissues of bighead carp (Aristichthys nobilis). Journal of Biochemistry Molecular Toxicology 24:250-259. 2010. [IF 1.96] Li GY, Xie P*, Fu J, Hao L, Xiong Q, Li HY. Microcystin-induced variations in transcription of GSTs in an omnivorous freshwater fish, goldfish. Aquatic Toxicology 88:75-80. 2008. [IF 3.52 ]

推荐链接
down
wechat
bug