个人简介

近年来主持有国家级、农业部、省、市、企业基金等多个研究项目，参加了国家、省、市攻关项目、基金项目的研究。获得湖北省科技进步二等奖1项，武汉市科技进步三等奖1项，农业部科技进步三等奖1项。现主持国家科技支撑计划项目等科研项目，总经费38万元。发表有研究论文80多篇。从1997年开始招收硕士研究生，目前已培养研究生26人，在读12人。

研究领域

鱼类病理学，营养与免疫，水产微生物学

1.水生动物医学方向，主要从事水生动物的病原与检测、水生动物免疫的特点和机理、水生动物免疫刺激剂的作用机理研究，鱼用药物的作用机理、代谢与残留以及开发应用等方面的研究；2.水生动物的营养与免疫方向，主要从事营养素的缺乏与替代对水生动物免疫的影响、各种添加剂和药物的使用与水生动物免疫的关系等方面的研究；3.水产微生物学方向，主要从事水生动物肠道微生物的组成特点、肠道微生物与免疫、微生物饲料添加剂和水质改良剂的作用机制与开发应用等方面的研究

近期论文

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Ren Y W, Li S S, Wu Z X, Zhou C C, Ding D, Chen X X*. The influences of Bacillus subtilis on the virulence of Aeromonas hydrophila and expression of luxS gene of both bacteria under co-cultivation. Current Microbiology, 2017, 74(6):718-724 石焱, 马徐发, 吴志新, 任雨薇, 陈孝煊*. 水雍菜浮床养殖模式下黄颡鱼肠道菌群结构分析. 华中农业大学学报, 2016, 35(2):69-76 Shao J F, Huang J, Guo Y N, Li L J, Liu X Q, Chen X X*, Yuan J F*. Up-regulation of nuclear factor E2-related factor 2 (Nrf2) represses the replication of SVCV. Fish & Shellfish Immunology, 2016, 58:474-482 张棋, 吴志新, 李景, 胡明, 石焱, 任雨薇, 陈孝煊*. 中华鳖肠道益生菌的筛选、鉴定与生长特性研究. 水生生物学报, 2015, 39(2):294-300 Li R Q, Ren Y W, Li J, Huang C, Shao J H, Chen X X, Wu Z X. Comparative pharmacokinetics of oxytetracycline in blunt-snout bream (Megalobrama amblycephala) with single and multiple-dose oral administration. Fish Physiology and Biochemistry, 2015, 41(3):803-809 彭小云, 刘红, 陈孝煊, 张棋, 袁娟, 刘佳佳, 吴志新. 嗜水气单胞菌和大肠杆菌LPS对草鱼免疫相关基因表达的影响. 华中农业大学学报, 2014,33(1):67-72 Yuan J, Li R Q, Shi Y, Peng X Y, Chen X X, Wu Z X. Pharmacokinetics of oxytetracycline in yellow catfish [Pelteobagrus fulvidraco (Richardson, 1846)] with a single and multiple-dose oral administration. Journal of Applied Ichthyology, 2014, 30(1):109-113 Wu Z X, Yu Y M, Chen X, Liu H, Yuan J F, Shi Y, Chen X X*. Effect of prebiotic konjac mannanoligosaccharide on growth performances, intestinal microflora, and digestive enzyme activities in yellow catfish, Pelteobagrus fulvidraco. Fish Physiology and Biochemistry, 2014, 40(3):763-771 Yang Y, Huang J, Li L J, Li Lin, Zhai Y H, Chen X X, Liu X Q, Wu Z X, Yuan J. Up-regulation of nuclear factor E2-Related factor 2 upon SVCV infection. Fish & Shellfish Immunology, 2014, 40(1):245-252 谢玲玲, 吴志新, 袁娟, 刘佳佳, 彭小云, 朱旭, 陈孝煊*.口灌氟苯尼考在黄鳝体内的药物代谢动力学及其残留. 华中农业大学学报, 2013,32(1):97-102 Wu Z X, Pang S F, Chen X X*, Yu Y M, Zhou J M, Chen X, Pang L J. Effect of Coriolus versicolor polysaccharides on the pematological and biochemical parameters and protection against Aeromonas hydrophila in allogynogenetic crucian carp (Corassius auratus gibelio). Fish Physiology and Biochemistry, 2013, 39(2):181-190 Wu Z X, Pang S F, Liu J J, Zhang Q, Fu S S, Du J, Chen X X*. Coriolus versicolor polysaccharides enhance the immune response of crucian carp (Corassius auratus gibelio) and protect against Aeromonas hydrophila. Journal of Applied Ichthyology, 2013, 29(3):562-568 Xie L L, Wu Z X*, Chen X X*, Li Q, Yuan J, Liu H, Yang Y. Pharmacokinetics of florfenicol and its metabolite, florfenicol amine, in rice field eel (Monopterus albus) after a signle-dose intramuscular or oral administration. Journal of Veterinary Pharmacology and Therapeutics, 2013, 36(3):229-235 Yang Q, Xie L L, Wu Z X, Chen X X, Yang Y, Liu J J, Zhang Q. Pharmacokinetics of florfenicol after oral administration in yellow catfish, Pelteobagrus fulvidraco. Journal of the World Aquaculture Society, 2013, 44(4):586-592 袁娟，李汝琴，彭小云，刘红，陈孝煊，吴志新. 土霉素在黄颡鱼肌肉组织中残留消除规律的研究. 中国农学通报, 2013,29(23):27-31 Tan Q S*, Liu Q, Chen X X*, Wang M, Wu Z X.. Growth performance, biochemical indices and hepatopancreatic function of grass carp, Ctenopharyngodon idellus, would be impaired by dietary rapeseed meal. Aquaculture, 2013, 414-415:119-126 杨毅, 李莉娟, 陈孝煊, 袁军法. 锦鲤疱疹病毒ORF134基因的克隆与表达. 华中农业大学学报, 2013,32(4):100-105 刘佳佳, 吴志新, 石焱, 姚卓凤, 李景, 彭小云, 陈孝煊*. 甘露寡糖对草鱼感染嗜水气单胞菌后细胞因子表达的调节. 淡水渔业, 2013,43(5)：31-36 Jia P, Zhu X, Zheng W, Zheng X C, Shi X J, Lan W S, Kan S F, Hua Q Y, Liu H, Chen X X. Isolation and genetic typing of infectious hematopoietic necrosis virus (IHNV) from cultured brook trout (Salvelinus fontinalis) in China. Bulletin of the European Association of Fish Pathologists, 2013, 33(5):150-157