研究领域
本课题组研究方向为水溶性纳米材料的可控制备及其在生物分离和生物标记领域的基础与应用研究。
主要研究内容:
1. 水溶性纳米晶的生长机制研究.以金属纳米晶为模型体系,研究纳米晶的水相生长机制,实现纳米晶的绿色合成.
2.纳米晶的表面修饰.利用无机、有机、聚合物、生物分子等对纳米晶进行表面修饰,赋予纳米晶识别功能,实现其与生物分子的特异性相互作用.
3.从磁性复合粒子出发,发展可与自动化技术兼容的核酸和蛋白高效快速分离方法。
4.利用具有磁光功能的水溶性纳米粒子进行免疫标记,发展可用于重大疾病如癌症、爱滋病等的临床免疫学快速检测方法。
近期论文
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Jian Guan, Lin Jiang, Jun Li, Wensheng Yang*, pH-dependent aggregation of histidine functionalized Au nanoparticles induced by Fe3+ ions, J. Phys. Chem. C, 2008, 112, 3267-3271.
Ziyang Lu, Yaqiong Qin, Jianyong Fang, Jing Sun, Jun Li, Fengqi Liu, Wensheng Yang*, “Monodispersed magnetizable silica composite particles from heteroaggregate of carboxylic polyst yrene latex and Fe3O4 nanoparticles”, Nanotechnology, 2008, 19, Art. No. 055602.
Jing Sun, Jiaqi Zhuang, Shaowei Guan, Wensheng Yang*, “Synthesis of Robust Water-Soluble ZnS:Mn/SiO2 Core/shell Nanoparticles”, J. Nanopart. Res., 2008, 10, 653-658.
Ziyang Lu, Jie Dai, Xiangning Song, Gang Wang, Wensheng Yang*, “Facile synthesis of Fe3O4/SiO2 composite nanoparticles from primary silica particles”, Colloids & Surfaces A, 2008, 317, 450-456.
Jian Guan, Lin Jiang, Lili Zhao, Jun Li, Wensheng Yang*, “pH-dependent selectivity of citrate functionalized Au nanoparticles to Pb2+ ion”, Colloids & Surfaces A, 2008, 325, 194-197.
Xiaohui Ji, Xiangning Song, Jun Li, Yubai Bai, Wengsheng Yang,* Xiaogang Peng*, “Size Control of Gold Nanocrystals in Citrate Reduction: The Third Role of Citrate”, J. Am. Chem. Soc., 2007, 129, 13939-13948.
Kui Zhao, Jun Li, Hongzhe Wang, Jiaqi Zhuang, Wensheng Yang*, “Stoichiometric Ratio Dependent Photoluminescence Quantum Yields of the Thiol Capping CdTe Nanocrystals”, J. Phys. Chem. C, 2007, 111, 5618-5621.
Yi Guo, Yudan Ma, Li Xu, Jun Li, Wensheng Yang*, “Conformational Change Induced Reversible Assembly/Disassembly of Poly-L-Lysine Functionalized Gold Nanoparticles”, J. Phys. Chem. C, 2007, 111, 9172-9176.
Wenping Jian, Jiaqi Zhuang, Wensheng Yang*, Yubai Bai, “Improved Photoluminescence of ZnS:Mn nanocrystals by microwave assisted growth of ZnS shell”, J. Lumin., 2007, 126, 735-740.
Kui Zhao, Jie Dai, Jiaqi Zhuang, Jun Li, Wensheng Yang*, “Highly efficient transfer of water soluble ZnS:Mn2+ nanocrystal into organic phase by 1-dodecanethiol”, Colloids & Surfaces A, 2007, 296,154-157.