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个人简介

李磊,教授,博士生导师。2003年5月获得美囯密歇根州立大学遗传学专业博士学位;2003-2007年在耶鲁大学从事博士后研究,致力于microRNA相关基因网络的研究。先后在《NatureGenetics》、《PNAS》、《PlantCell》、《GenomeBiology》、《ThePlantJournal》等国际学术期刊以第一作者或通讯作者发表文章多篇。主持美国自然科学基金等项目。

研究领域

1.microRNA相关基因网络的构建与功能研究; 2.基于microRNA基因网络的植物比较基因组学; 3.植物生殖系统与果实发育的遗传调控,基因网络与互作。

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

1.ZhaoX,ZhangH,LiL.IdentificationandanalysisoftheproximalpromotersofmicroRNAgenesinArabidopsis.Genomics.Publishedonline. 2.ZhaoX,LiL.ComparativeanalysisofmicroRNApromotersinArabidopsisandrice.Genomics,Proteomics&Bioinformatics.Publishedonline. 3.ZhangH,LiL.SQUAMOSAPromoterBindingProtein-Like7regulatedmicroRNA408isrequiredforvegetativedevelopmentinArabidopsis.ThePlantJournal.Publishedonline. 4.LiL,DengXW.Transcriptomeprofilinginrice.In“GeneticsandGenomicsofRice.”QZhang,RWing,Eds.Springer.Inpress. 5.ZhangH,DengXW,LiL.Analysisofallele-specificgeneexpressionusingatarget-orientedtilingmicroarrayassay.MethodsinMolecularBiology.Inpress. 6.AryalR,YangX,YuQ,SunkarR,LiL,MingR(2012)Asymmetricpurine-pyrimidinedistributionincellularsmallRNApopulationofpapaya.BMCGenomics13,682. 7.YangX,LiL(2012)AnalyzingthemicroRNAtranscriptomeinplantsusingdeepsequencingdata.Biology1,297-310. 8.YangX,ZhangH,LiL(2012)AlternativemRNAprocessingincreasesthecomplexityofmicroRNA-basedgeneregulationinArabidopsis.ThePlantJournal70,421-431. 9.YangX,LiL(2011)miRDeep-P:acomputationaltoolforanalyzingthemicroRNAtranscriptomeinplants.Bioinformatics27,2614-2615. 10.OikawaPY,GiebelBM,O’ReillySternbergLdaS,LiL,TimkoMP,SwartPK,RiemerDD,MakJE,LerdauMT(2011)Leafandrootpectinmethylesteraseactivityand13C/12CstableisotopicratiomeasurementsofmethanolemissionsgiveinsightintomethanolproductioninLycopersiconesculentum.NewPhytologist191,1031-1040. 11.YangX,ZhangH,LiL(2011)Globalanalysisofgene-levelmicroRNAexpressioninArabidopsisusingdeepsequencingdata.Genomics98,40-46. 12.OikawaPY,LiL,TimkoMP,MakJE,LerdauMT(2011)ShorttermchangesinmethanolemissionandpectinmethylesteraseactivityarenotdirectlyaffectedbylightinLycopersiconesculentum.Biogeosciences8,1023-1030. 13.WuN,YangX,LiL(2011)IdentificationoffeedforwardloopscomposedofmicroRNAsandtranscriptionfactorsinArabidopsis.JournalofBiochemistryandMolecularBiologyinthePost-GenomicEra1,5. 14.ZhangH,HeH,WangX,WangX,YangX,LiL§,DengXW§(2011)Genome-widemappingoftheHY5-mediatedgenenetworksinArabidopsisthatinvolvebothtranscriptionalandpost-transcriptionalregulations.ThePlantJournal65,346-358.§Co-corresponding. 15.HeH,ZhangH,WangX,WuN,YangX,ChenR,LiY,DengXW§,LiL§(2010)Developmentofaversatile,target-orientedtilingmicroarrayassayformeasuringallele-specificgeneexpression.Genomics96,308-315.§Co-corresponding. 16.WangX,YuZ,YangX,DengXW,LiL(2009)Transcriptionallyactivegenefragmentsderivedfrompotentiallyfast-evolvingdonorgenesinthericegenome.Bioinformatics25,1215-1218. 17.PengZY,ZhangH,LiuT,DzikiewiczKM,LiS,WangX,HuG,ZhuZ,WeiX,ZhuQH,SunZ,GeS,MaL,LiL§,DengXW§(2009)Characterizationofthegenomeexpressiontrendsintheheading-stagepanicleofsixricelineages.Genomics93,169-178.§Co-corresponding. 18.LiL,HeH,ZhangJ,WangX,BaiS,StolcV,TongprasitW,YoungND,YuO,DengXW(2008)TranscriptionalanalysisofhighlysyntenicregionsbetweenMedicagotruncatulaandGlycinemaxusingtilingmicroarrays.GenomeBiology9,R57. 19.ZhangHY,HeH,ChenLB,LiL,LiangMZ,WangXF,LiuXG,HeGM,ChenRS,MaLG,andDengXW(2008)Agenome-widetranscriptionanalysisrevealsaclosecorrelationofpromoterINDELpolymorphismandheteroticgeneexpressioninricehybrids.MolecularPlant1,720-731. 20.LiL,DengXW(2008)Microarray-basedapproachestoricetranscriptomeanalysis.In“Ricebiologyinthegenomicsera.”HHirano,AHirai,YSano,TSasaki,Eds.Springer.p.37-52. 21.KikuchiS,WangG-L,LiL(2007)Genome-wideRNAexpressionprofiling.In“Ricefunctionalgenomics:Challenges,progressandprospects.”NUpadhyaya,Eds.Springer.p.36-63. 22.LiL,WangX,SasidharanR,StolcV,DengW,HeH,KorbelJ,ChenX,TongprasitW,RonaldP,ChenR,GersteinM,DengXW(2007)Globalidentificationandcharacterizationoftranscriptionallyactiveregionsinthericegenome.PLoSONE2,e294. 23.SuN,HeK,JiaoY,ChenC,ZhouJ,LiL,BaiS,LiX,DengXW(2007)Distinctreorganizationofthegenometranscriptionassociateswithorganogenesisofsomaticembryo,shoots,androotsinrice.PlantMolecularBiology63,337-349. 24.LiL,WangX,StolcV,LiX,ZhangD,SuN,TongprasitW,LiS,ChengZ,WangJ,DengXW(2006)Genome-widetranscriptionanalysesinriceusingtilingmicroarrays.NatureGenetics38,124-129. 25.WangX,HeH,LiL,ChenR,DengXW,LiS(2006)NMPP-Auser-customizedNimblegenmicroarraydataprocessingpipeline.Bioinformatics22,2955-2957. 26.ZhangS,ChenC,LiL,MengL,SinghJ,JiangN,DengXW,HeZH,LemauxPG(2005)Evolutionaryexpansion,genestructure,andexpressionofthericewall-associatedkinasegenefamily.PlantPhysiology139,1107-1124. 27.StolcV,LiL,WangX,LiX,SuN,TongprasitW,HanB,XueY,LiJ,SnyderM,GersteinM,WangJ,DengXW(2005)Apilotstudyoftranscriptionunitanalysisinriceusingoligonucleotidetiling-pathmicroarray.PlantMolecularBiology59,137-149. 28.LiL,WangX,XiaM,StolcV,SuN,PengZ,LiS,WangJ,WangX,DengXW(2005)Tilingmicroarrayanalysisofricechromosome10toidentifythetranscriptomeandrelateitsexpressiontochromosomalarchitecture.GenomeBiology6,R52. 29.LiL,DengXW(2005)Itrunsinthefamily:regulationofbrassinosteroidsignalingbytheBZR1-BES1classoftranscriptionfactors.TrendsinPlantScience10,266-268. 30.LiL,WangX,LiX,SuN,StolcV,HanB,LiJ,XueY,WangJ,DengXW(2005)Towardgenome-widetranscriptionalanalysisinriceusingMASoligonucleotidetiling-pathmicroarrays.In“RiceIsLife:ScientificPerspectivesforthe21stCentury.”KToriyama,KLHeong,BHardy,Eds.p.80-83. 31.JiaoY,JiaP,WangX,SuN,YuS,ZhangD,MaL,FengQ,JinZ,LiL,XueY,ChengZ,ZhaoH,HanB,DengXW(2005)Atilingmicroarrayexpressionanalysisofricechromosome4suggestsachromosome-levelregulationoftranscription.PlantCell17,1641-1657. 32.LiL,ZhaoY,McCaigBC,WingerdBA,WangJ,WhalonME,PicherskyE,HoweGA(2004)ThetomatohomologofCORONATINE-INSENSITIVE1isrequiredforthematernalcontrolofseedmaturation,jasmonate-signaleddefenseresponses,andglandulartrichomedevelopment.PlantCell16,126-143. 33.LiL,DengXW(2003)TheCOP9signalosome:analternativelidforthe26Sproteasome?TrendsinCellBiology13,507-509. 34.LiL,LiC,LeeGI,HoweGA(2002)Distinctrolesforjasmonatesynthesisandactioninthesystemicwoundresponseoftomato.ProceedingsoftheNationalAcademyofSciencesUSA99,6416-6421. 35.HoweGA,LiL,LeeGI,LiC,ShafferD(2002)Geneticdissectionofinducedresistanceintomato.In“Inducedresistanceinplantsagainstinsectsanddiseases”.ASchmitt,BMauch-Mani,Eds.p.47-52. 36.LiL,LiC,HoweGA(2001)Geneticanalysisofwoundsignalingintomato:Evidenceforadualroleofjasmonicacidindefenseandfemalefertility.PlantPhysiology127,1414-1417. 37.LiL,HoweGA(2001)Alternativesplicingofprosysteminpre-mRNAproducestwoisoformsthatareactiveassignalsinthewoundresponsepathway.PlantMolecularBiology46,409-419. 38.HoweGA,LeeGI,ItohA,LiL,DeRocherA(2000)CytochromeP450-dependentmetabolismofoxylipinsintomato:cloningandexpressionofalleneoxidesynthaseandfattyacidhydroperoxidelyase.PlantPhysiology123,711-724.

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